Research map: Scoping review on polycystic liver disease in PKD1/PKD2 gene carriers: genetic aspects, pathophysiology and therapeutic approaches.

Back to the article

Papers in this map

  1. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement · David Moher · 2009 · 65241 citations · Cited by this paper
  2. Molecular Biomarkers and Risk Prediction Models for Acute Kidney Injury Following Liver Transplantation: A Review · 2026 · Related
  3. Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells · Surya M. Nauli · 2003 · 2070 citations · Cited by this paper
  4. Long-term Outcomes of Percutaneous Biodegradable Stent Placement for Hepaticojejunostomy Strictures · 2026 · Related
  5. Organogenesis and Development of the Liver · Karim Si‐Tayeb · 2010 · 806 citations · Cited by this paper
  6. Reframing MASLD: A Hepatic Condition with Systemic Clinical Impact · 2026 · Related
  7. PKHD1, the Polycystic Kidney and Hepatic Disease 1 Gene, Encodes a Novel Large Protein Containing Multiple Immunoglobulin-Like Plexin-Transcription–Factor Domains and Parallel Beta-Helix 1 Repeats · Luiz Fernando Onuchic² · 2002 · 518 citations · Cited by this paper
  8. Candesartan Cilexetil Restores Renal Endothelial Function Through Modulation of the ADMA–DDAH–eNOS Pathway in Experimental ACLF-Associated Renal Dysfunction · 2026 · Related
  9. Mutations in GANAB , Encoding the Glucosidase IIα Subunit, Cause Autosomal-Dominant Polycystic Kidney and Liver Disease · Binu Porath · 2016 · 483 citations · Cited by this paper
  10. Overlap Syndromes and Associated Immunoglobulin-G4-Related Liver Diseases · 2026 · Related
  11. Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases · Émilie Cornec-Le Gall · 2017 · 418 citations · Cited by this paper
  12. Recurrent Liver Failure due to SCYL1 Deficiency: A Report of 2 Cases and a Review of the Literature · 2026 · Related
  13. Effectiveness of Vasopressin V2 Receptor Antagonists OPC-31260 and OPC-41061 on Polycystic Kidney Disease Development in the PCK Rat · Xiaofang Wang · 2005 · 336 citations · Cited by this paper
  14. Assessment of Liver Volumes Using Semiautomated Segmentation and Development of a Predictive Formula in the Indian Population · 2026 · Related
  15. Risk Factors for the Development of Hepatic Cysts in Autosomal Dominant Polycystic Kidney Disease · Patricia A. Gabow · 1990 · 303 citations · Cited by this paper
  16. Acute Kidney Injury After Acute Viral Hepatitis A in Adults: Incidence, Predictors, and Impact on Outcomes · 2026 · Related
  17. Structure of the human PKD1-PKD2 complex · Qiang Su · 2018 · 295 citations · Cited by this paper
  18. Inflammatory Myofibroblastic Tumour of the Liver: Experience From a Specialised Paediatric Liver Centre · 2026 · Related
  19. Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them Into Intracellular Ca2+ and cAMP Signaling · Anatoliy I. Masyuk · 2006 · 294 citations · Cited by this paper
  20. Methodological considerations in the interpretation of non-invasive surrogate markers in a post hoc analysis of pemafibrate in MASLD · 2026 · Related
  21. microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism · Sachin S. Hajarnis · 2017 · 217 citations · Cited by this paper
  22. Diagnosis and management of polycystic liver disease · Tom J.G. Gevers · 2013 · 213 citations · Cited by this paper
  23. Isolated polycystic liver disease genes define effectors of polycystin-1 function · Whitney Besse · 2017 · 213 citations · Cited by this paper
  24. Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease · Hao Lu · 2017 · 210 citations · Cited by this paper
  25. Adult Polycystic Liver Disease · J.-F. Gigot · 1997 · 190 citations · Cited by this paper
  26. Fibrocystin/Polyductin, Found in the Same Protein Complex with Polycystin-2, Regulates Calcium Responses in Kidney Epithelia · Shixuan Wang · 2007 · 190 citations · Cited by this paper
  27. MicroRNA15a modulates expression of the cell-cycle regulator Cdc25A and affects hepatic cystogenesis in a rat model of polycystic kidney disease · Seung Ok Lee · 2008 · 181 citations · Cited by this paper
  28. Cholangiocyte primary cilia are chemosensory organelles that detect biliary nucleotides via P2Y 12 purinergic receptors · Anatoliy I. Masyuk · 2008 · 171 citations · Cited by this paper
  29. Cholangiocyte primary cilia in liver health and disease · Anatoliy I. Masyuk · 2008 · 168 citations · Cited by this paper
  30. PPARα agonist fenofibrate enhances fatty acid β-oxidation and attenuates polycystic kidney and liver disease in mice · Ronak Lakhia · 2017 · 153 citations · Cited by this paper
  31. Patients with isolated polycystic liver disease referred to liver centres: clinical characterization of 137 cases · Loes van Keimpema · 2010 · 150 citations · Cited by this paper
  32. Laparoscopic Treatment of Nonparasitic Liver Cysts: Adequate Selection of Patients and Surgical Technique · J. F. Gigot · 1996 · 142 citations · Cited by this paper
  33. ACG Clinical Guideline: Focal Liver Lesions · Catherine T Frenette · 2024 · 119 citations · Cited by this paper
  34. Clinical manifestations of autosomal recessive polycystic kidney disease (ARPKD): kidney-related and non-kidney-related phenotypes · Rainer Büscher · 2013 · 111 citations · Cited by this paper
  35. Biliary Dysgenesis in the PCK Rat, an Orthologous Model of Autosomal Recessive Polycystic Kidney Disease · Tatyana V. Masyuk · 2004 · 110 citations · Cited by this paper
  36. EASL Clinical Practice Guidelines on the management of cystic liver diseases · Joost P.H. Drenth · 2022 · 107 citations · Cited by this paper
  37. Mechanisms of ciliogenesis suppression in dividing cells · Hidemasa Goto · 2016 · 102 citations · Cited by this paper
  38. Activation of Trpv4 Reduces the Hyperproliferative Phenotype of Cystic Cholangiocytes From an Animal Model of ARPKD · Sergio A. Gradilone · 2010 · 98 citations · Cited by this paper
  39. Mammalian Target of Rapamycin Regulates Vascular Endothelial Growth Factor–Dependent Liver Cyst Growth in Polycystin-2–Defective Mice · Carlo Spirlı̀ · 2009 · 96 citations · Cited by this paper

Source: OpenAlex (CC0)