Research map: The effect of IFNAR2 and TYK2 gene expressions and serum IFN-α levels on disease severity in COVID-19 patients

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  1. Longitudinal analyses reveal immunological misfiring in severe COVID-19 · Carolina Gonçalves de Oliveira Lucas · 2020 · 2326 citations · Cited by this paper
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  12. Cardiometabolic dysfunction is associated with calcium carbide intake in male Wistar rat: implication of dyslipidemia, oxidative stress, and inflammation · 2026 · Related
  13. Overview of SARS-CoV-2 genome-encoded proteins · Chongzhi Bai · 2021 · 218 citations · Cited by this paper
  14. Protective effects of sitagliptin against cyclophosphamide-induced hepatorenal toxicity in rats: biochemical, histological, and immunohistochemical evaluation · 2026 · Related
  15. Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy? · Lok-Yin Roy Wong · 2021 · 204 citations · Cited by this paper
  16. Acute oral toxicity and anti-inflammatory activity of the ethanolic extract from Carpobrotus edulis (L.) N. E. Br., var. rubescens Druce in Wistar rats · 2026 · Related
  17. COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic Strategies · Renuka Raman · 2021 · 188 citations · Cited by this paper
  18. A retrospective evaluation of clinical, diagnostic and treatment aspects of 154 feline pyometra cases presented at the University Veterinary Hospital, Universiti Putra Malaysia · 2026 · Related
  19. Microstructure, pathophysiology, and potential therapeutics of COVID‐19: A comprehensive review · Satarudra Prakash Singh · 2020 · 174 citations · Cited by this paper
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  21. The Role of Structure in the Biology of Interferon Signaling · Mark R. Walter · 2020 · 159 citations · Cited by this paper
  22. Virology, pathogenesis, diagnosis and in-line treatment of COVID-19 · Pavan Kumar Samudrala · 2020 · 149 citations · Cited by this paper
  23. SARS-CoV-2 Nonstructural Protein 1 Inhibits the Interferon Response by Causing Depletion of Key Host Signaling Factors · Anil Kumar · 2021 · 118 citations · Cited by this paper
  24. Interferon Receptor Trafficking and Signaling: Journey to the Cross Roads · Natacha Zanin · 2021 · 106 citations · Cited by this paper
  25. IFN-γ, should not be ignored in SLE · Wenping Liu · 2022 · 89 citations · Cited by this paper
  26. SARS-CoV-2 Disrupts Proximal Elements in the JAK-STAT Pathway · Da‐Yuan Chen · 2021 · 87 citations · Cited by this paper
  27. Mendelian randomization analysis identified genes pleiotropically associated with the risk and prognosis of COVID-19 · Di Liu · 2020 · 71 citations · Cited by this paper
  28. JAK inhibitors and COVID-19 · Gabriel Levy · 2022 · 68 citations · Cited by this paper
  29. COVID-19 genetic risk variants are associated with expression of multiple genes in diverse immune cell types · Benjamin Joachim Schmiedel · 2021 · 64 citations · Cited by this paper
  30. SARS-CoV-2 Infection-Induced Promoter Hypomethylation as an Epigenetic Modulator of Heat Shock Protein A1L (HSPA1L) Gene · Jibran Sualeh Muhammad · 2021 · 51 citations · Cited by this paper
  31. IFNAR2 relevance in the clinical outcome of individuals with severe COVID-19 · Ingrid Fricke-Galindo · 2022 · 49 citations · Cited by this paper
  32. A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients · Mohammad Sadegh Soltani‐Zangbar · 2022 · 48 citations · Cited by this paper
  33. Loss-of-function mutations in IFNAR2 in COVID-19 severe infection susceptibility · Sandra Paulina Smieszek · 2021 · 47 citations · Cited by this paper
  34. Genome-wide association studies of COVID-19: Connecting the dots · Leonardo Capistrano Ferreira · 2022 · 43 citations · Cited by this paper
  35. Down syndrome and type I interferon: not so simple · Louise Malle · 2021 · 41 citations · Cited by this paper
  36. Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α · Maria Alice Freitas Queiroz · 2024 · 41 citations · Cited by this paper
  37. Cytokine profiles dynamics in COVID-19 patients: a longitudinal analysis of disease severity and outcomes · Sara Ghaffarpour · 2025 · 41 citations · Cited by this paper
  38. Unraveling Risk Genes of COVID-19 by Multi-Omics Integrative Analyses · Ancha V. Baranova · 2021 · 36 citations · Cited by this paper
  39. Mechanism of Rhinovirus Immunity and Asthma · Zuqin Yang · 2021 · 34 citations · Cited by this paper

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