Research map: Oral microbiota dysbiosis related to the cortical thinning and cognitive impairment in cerebral small vessel disease

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Papers in this map

  1. Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors · Stephen S. Dominy · 2019 · 2004 citations · Cited by this paper
  2. Interplay between genetically predicted gut microbiota and chronic apical periodontitis: a Mendelian randomization analysis · 2026 · Related
  3. Interactions between the microbiota, immune and nervous systems in health and disease · Thomas C. Fung · 2017 · 1963 citations · Cited by this paper
  4. Oral microbiome dynamics across periodontitis severity stratified by type 2 diabetes status · 2026 · Related
  5. Brain charts for the human lifespan · Richard A. I. Bethlehem · 2022 · 1904 citations · Cited by this paper
  6. Bacterial contamination and diversity of dental unit waterlines across dental specialties, outlets and distinct times: heterotrophic bacteria counting and sequencing analysis · 2026 · Related
  7. Neuroimaging standards for research into small vessel disease—advances since 2013 · Marco Duering · 2023 · 1124 citations · Cited by this paper
  8. Filtration-enriched metabolites and their association with salivary microbiota: a combined two-cohort analysis · 2026 · Related
  9. Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden · Julie Staals · 2014 · 1073 citations · Cited by this paper
  10. Ecological succession in the oral microbiome drives caries pathogenesis: a shift from antagonistic to synergistic cross-kingdom networks · 2026 · Related
  11. CNS small vessel disease · Rocco J. Cannistraro · 2019 · 664 citations · Cited by this paper
  12. Interactions between taste and oral microbiome: mechanisms and implications for oral and systemic diseases · 2026 · Related
  13. The oral microbiome: diversity, biogeography and human health · Jonathon L. Baker · 2023 · 654 citations · Cited by this paper
  14. Shotgun metagenomic profiling reveals ecological and functional alterations of the oral microbiome in craniosynostosis · 2026 · Related
  15. Atrophy of the medial occipitotemporal, inferior, and middle temporal gyri in non-demented elderly predict decline to Alzheimer’s disease☆ · Antonio J. Convit · 2000 · 369 citations · Cited by this paper
  16. Epidemiological characteristics and co-occurrence patterns of Rothia species and respiratory pathogens: from population surveillance to mechanistic insights · 2026 · Related
  17. Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease · Minghui Wang · 2016 · 353 citations · Cited by this paper
  18. Buprenorphine enhances Streptococcus mutans virulence and biofilm formation · 2026 · Related
  19. Prevalence, risk factors and consequences of cerebral small vessel diseases: data from three Asian countries · Saima Hilal · 2017 · 238 citations · Cited by this paper
  20. Periodontal diseases and association with atherosclerotic disease · David Herrera · 2020 · 193 citations · Cited by this paper
  21. Global Burden of Small Vessel Disease–Related Brain Changes on MRI Predicts Cognitive and Functional Decline · Hanna Jokinen · 2019 · 189 citations · Cited by this paper
  22. Longitudinal patterns of leukoaraiosis and brain atrophy in symptomatic small vessel disease · Christian Lambert · 2016 · 159 citations · Cited by this paper
  23. Microbial protection and virulence in periodontal tissue as a function of polymicrobial communities: symbiosis and dysbiosis · Frank A. Roberts · 2015 · 152 citations · Cited by this paper
  24. Brain Atrophy and Cerebral Small Vessel Disease · Arani Nitkunan · 2010 · 137 citations · Cited by this paper
  25. Potential Bidirectional Relationship Between Periodontitis and Alzheimer’s Disease · Daniela Liccardo · 2020 · 130 citations · Cited by this paper
  26. Polymicrobial Infections In Brain Tissue From Alzheimer’s Disease Patients · Diana Pisa · 2017 · 118 citations · Cited by this paper
  27. Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway · Shuang Lei · 2023 · 117 citations · Cited by this paper
  28. Intracerebral hemorrhage and deep microbleeds associated with cnm-positive Streptococcus mutans; a hospital cohort study · Shuichi Tonomura · 2016 · 94 citations · Cited by this paper
  29. Chronic periodontitis induces microbiota-gut-brain axis disorders and cognitive impairment in mice · Xue Li · 2020 · 79 citations · Cited by this paper
  30. Amyloid burden, cerebrovascular disease, brain atrophy, and cognition in cognitively impaired patients · Byoung Seok Ye · 2014 · 74 citations · Cited by this paper
  31. The impact of periodontitis on vascular endothelial dysfunction · Qian Li · 2022 · 56 citations · Cited by this paper
  32. Novelties on Neuroinflammation in Alzheimer’s Disease–Focus on Gut and Oral Microbiota Involvement · Cristina Popescu · 2024 · 50 citations · Cited by this paper
  33. Linking cortical atrophy to white matter hyperintensities of presumed vascular origin · Carola Mayer · 2020 · 47 citations · Cited by this paper
  34. Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study · Christiane Pink · 2023 · 44 citations · Cited by this paper
  35. A distinctive subgingival microbiome in patients with periodontitis and Alzheimer's disease compared with cognitively unimpaired periodontitis patients · Hee Sam Na · 2023 · 43 citations · Cited by this paper
  36. Periodontitis and brain magnetic resonance imaging markers of Alzheimer's disease and cognitive aging · Tom Rubinstein · 2024 · 43 citations · Cited by this paper
  37. Oral pathogens exacerbate Parkinson’s disease by promoting Th1 cell infiltration in mice · Xuebing Bai · 2023 · 39 citations · Cited by this paper
  38. Profiles of subgingival microbiomes and gingival crevicular metabolic signatures in patients with amnestic mild cognitive impairment and Alzheimer’s disease · Che Qiu · 2024 · 36 citations · Cited by this paper
  39. Association Between Oral Microbiota and Human Brain Glioma Grade: A Case-Control Study · Yuqi Wen · 2021 · 32 citations · Cited by this paper

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