Research map: Daphnetin ameliorates skin inflammation by selectively inhibiting transient receptor potential vanilloid 3 channels

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  1. Microbiota and maintenance of skin barrier function · Tamia A. Harris-Tryon · 2022 · 664 citations · Cited by this paper
  2. Characteristics Three waves of pyripyropene fungal alkaloids and synthetic derivatives targeting ACAT2 as insecticides, anti-atherosclerosis and anticancer agents. · 2026 · Related
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  4. Low-molecular-weight fucoidan inhibits HMGB1-induced thromboinflammation by modulating HMGB1-TLR4 axis · 2026 · Related
  5. Skin Barrier and Calcium · Sang Eun Lee · 2018 · 174 citations · Cited by this paper
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  7. Daphnetin inhibits proliferation and inflammatory response in human HaCaT keratinocytes and ameliorates imiquimod-induced psoriasis-like skin lesion in mice · Jintao Gao · 2020 · 166 citations · Cited by this paper
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  9. Antioxidant activities of coumarins from Korean medicinal plants and their structure–activity relationships · Phương Thiện Thương · 2009 · 144 citations · Cited by this paper
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  11. Skin homeostasis: Mechanism and influencing factors · Qian Jiao · 2024 · 128 citations · Cited by this paper
  12. CTSB-Associated Inflammation and Macrophage Interaction in Heart Failure Following Myocardial Infarction and Potential Therapeutic Implications of Quercetin · 2026 · Related
  13. PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes · Jiahui Zhao · 2020 · 120 citations · Cited by this paper
  14. S14G-humanin (HNG) ameliorates diabetic nephropathy tubular injury by inhibiting Z-DNA/ZBP1-mediated necroptosis · 2026 · Related
  15. Therapeutic effects of daphnetin on adjuvant-induced arthritic rats · Qin Feng Gao · 2008 · 82 citations · Cited by this paper
  16. Induction and Propagation of Ferroptosis Evasion by FTH1P7 Drives Sorafenib Resistance in Hepatocellular Carcinoma · 2026 · Related
  17. Scutellarein attenuates atopic dermatitis by selectively inhibiting transient receptor potential vanilloid 3 channels · Yujing Wang · 2022 · 65 citations · Cited by this paper
  18. A functional coupling of TRPA1 and TMEM16A channels regulates endothelium-dependent hyperpolarization-mediated vasorelaxation of mesenteric resistance arteries in healthy and septic mice · 2026 · Related
  19. Antipruritic Effect of Natural Coumarin Osthole through Selective Inhibition of Thermosensitive TRPV3 Channel in the Skin · Xiaoying Sun · 2018 · 62 citations · Cited by this paper
  20. Natural Coumarin Derivatives Activating Nrf2 Signaling Pathway as Lead Compounds for the Design and Synthesis of Intestinal Anti-Inflammatory Drugs · Luiz Cláudio Di Stasi · 2023 · 58 citations · Cited by this paper
  21. A plant‐derived TRPV3 inhibitor suppresses pain and itch · Yalan Han · 2021 · 57 citations · Cited by this paper
  22. Inhibition of the Warm Temperature–Activated Ca2+-Permeable Transient Receptor Potential Vanilloid TRPV3 Channel Attenuates Atopic Dermatitis · Yaxuan Qu · 2019 · 53 citations · Cited by this paper
  23. Structural mechanism of TRPV3 channel inhibition by the anesthetic dyclonine · Arthur Neuberger · 2022 · 46 citations · Cited by this paper
  24. Daphnetin ameliorates 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis through Nrf-2-Keap1 and NF-κB pathways · Abhishek Kumar · 2016 · 41 citations · Cited by this paper
  25. Daphne giraldii Nitsche (Thymelaeaceae): Phytochemistry, pharmacology and medicinal uses · Shuang Han · 2019 · 41 citations · Cited by this paper
  26. 7,8-Dihydroxycoumarin Alleviates Synaptic Loss by Activated PI3K-Akt-CREB-BDNF Signaling in Alzheimer’s Disease Model Mice · Yan Li · 2022 · 33 citations · Cited by this paper
  27. Daphnetin, a Coumarin in Genus Stellera Chamaejasme Linn: Chemistry, Bioactivity and Therapeutic Potential · Sijin Hang · 2022 · 32 citations · Cited by this paper
  28. The Black Box Illuminated: Signals and Signaling · Francesca Mascia · 2011 · 31 citations · Cited by this paper
  29. Daphnetin inhibits inflammation in the NZB/W F1 systemic lupus erythematosus murine model via inhibition of NF-κB activity · Min Li · 2016 · 28 citations · Cited by this paper
  30. 7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-κB signaling · Yue Wang · 2013 · 27 citations · Cited by this paper
  31. Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch · Leigh Ann Nattkemper · 2023 · 23 citations · Cited by this paper
  32. Daphnetin contributes to allergen-induced Th2 cytokine expression and type 2-immune responses in atopic dermatitis and asthma · Yi C. Zhang · 2022 · 22 citations · Cited by this paper
  33. Syntheses and evaluation of daphnetin derivatives as novel G protein-coupled receptor inhibitors and activators · Yinan Wang · 2020 · 18 citations · Cited by this paper
  34. Transient receptor potential vanilloid 3 expression is increased in non‐lesional skin of atopic dermatitis patients · Nikolett Vasas · 2022 · 15 citations · Cited by this paper
  35. The molecular effects underlying the pharmacological activities of daphnetin · Zhifeng Wei · 2024 · 15 citations · Cited by this paper
  36. TRPV3 calcium channel at the crossroads of epidermal differentiation and inflammation · Emma Fraillon · 2025 · 3 citations · Cited by this paper

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