Research map: Bioactive Natural and Synthetic Chalcones: Brazil as a Research Powerhouse in Discovery and Innovation

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  1. SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules · Antoine Daina · 2017 · 18239 citations · Cited by this paper
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  14. Furagin Derivatives—Nitrofuran‐Based Hydrazones as Potential Dual Inhibitors of Thioredoxin Reductase and Carbonic Anhydrases · 2026 · Related
  15. Chalcone: A Privileged Structure in Medicinal Chemistry · Chunlin Zhuang · 2017 · 1466 citations · Cited by this paper
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  17. Simple Selection Criteria for Drug-like Chemical Matter · Ingo Muegge · 2001 · 1347 citations · Cited by this paper
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  19. A Bioavailability Score · Yvonne Connolly Martin · 2005 · 1033 citations · Cited by this paper
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  21. Lipophilicity in drug discovery · Michael J. Waring · 2010 · 880 citations · Cited by this paper
  22. Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates · B.C. Doak · 2014 · 841 citations · Cited by this paper
  23. The Design of Leadlike Combinatorial Libraries · Simon J. Teague · 1999 · 826 citations · Cited by this paper
  24. Lessons Learnt from Assembling Screening Libraries for Drug Discovery for Neglected Diseases · Ruth Brenk · 2007 · 723 citations · Cited by this paper
  25. Exploring Pharmacological Significance of Chalcone Scaffold: A Review · Nilanchala Sahu · 2012 · 587 citations · Cited by this paper
  26. Finding the sweet spot: the role of nature and nurture in medicinal chemistry · Michael M. Hann · 2012 · 421 citations · Cited by this paper
  27. Naturally occurring chalcones and their biological activities · Zsuzsanna Rozmer · 2014 · 388 citations · Cited by this paper
  28. Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence · Bahare Salehi · 2021 · 350 citations · Cited by this paper
  29. Trends in Utilization of the Pharmacological Potential of Chalcones · Daniela Ilieva Batovska · 2010 · 347 citations · Cited by this paper
  30. Condensationen von Ketonen mit Aldehyden · L. Claisen · 1881 · 196 citations · Cited by this paper
  31. Structure-Activity and Lipophilicity Relationships of Selected Antibacterial Natural Flavones and Flavanones of Chilean Flora · Javier Echeverría · 2017 · 162 citations · Cited by this paper
  32. Potential pharmacological uses of chalcones: a patent review (from June 2011 – 2014) · María João Matos · 2015 · 161 citations · Cited by this paper
  33. The Complete Mechanism of an Aldol Condensation · Charles L. Perrin · 2016 · 142 citations · Cited by this paper
  34. A comprehensive review of chalcone derivatives as antileishmanial agents · Marcos Vinicius Palmeira-Mello · 2018 · 138 citations · Cited by this paper
  35. Prediction of Synthetic Accessibility Based on Commercially Available Compound Databases · Yoshifumi Fukunishi · 2014 · 111 citations · Cited by this paper
  36. Ueber die Einwirkung von Aceton auf Furfurol und auf Bittermandelöl bei Gegenwart von Alkalilauge · J. Gustav Schmidt · 1881 · 105 citations · Cited by this paper
  37. Applications of SGLT2 inhibitors beyond glycaemic control · Daniel V. O’Hara · 2024 · 100 citations · Cited by this paper
  38. Pyrano chalcones and a flavone from Neoraputia magnifica and their Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase-inhibitory activities · Daniela M. Tomazela · 2000 · 84 citations · Cited by this paper
  39. Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase · Clarissa Campos Barbosa de Castro · 2015 · 84 citations · Cited by this paper

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