Research map: Improving T-cell engager efficacy in glioblastoma with multi-antigen targeting and novel delivery approaches

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  1. Radiotherapy Plus Concomitant and Adjuvant Temozolomide for Glioblastoma · Roger Stupp · 2005 · 22129 citations · Cited by this paper
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  5. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial · Roger Stupp · 2009 · 7879 citations · Cited by this paper
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  17. Population-Based Studies on Incidence, Survival Rates, and Genetic Alterations in Astrocytic and Oligodendroglial Gliomas · Hiroko Ohgaki · 2005 · 1384 citations · Cited by this paper
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  21. Transforming growth factor β1 inhibits expression of NKp30 and NKG2D receptors: Consequences for the NK-mediated killing of dendritic cells · Roberta Castriconi · 2003 · 720 citations · Cited by this paper
  22. T cell-engaging therapies — BiTEs and beyond · Maria-Elisabeth Goebeler · 2020 · 653 citations · Cited by this paper
  23. Chemotherapy resistance of glioblastoma stem cells · Adriana Eramo · 2006 · 635 citations · Cited by this paper
  24. Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. · Noriaki Sugawa · 1990 · 598 citations · Cited by this paper
  25. A Cellular Trojan Horse for Delivery of Therapeutic Nanoparticles into Tumors · Mi-Ran Choi · 2007 · 591 citations · Cited by this paper
  26. CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity · Bryan D. Choi · 2019 · 579 citations · Cited by this paper
  27. Stem cell-associated heterogeneity in Glioblastoma results from intrinsic tumor plasticity shaped by the microenvironment · Anne Dirkse · 2019 · 565 citations · Cited by this paper
  28. IDO Expression in Brain Tumors Increases the Recruitment of Regulatory T Cells and Negatively Impacts Survival · Derek Alan Wainwright · 2012 · 479 citations · Cited by this paper
  29. Intraventricular CARv3-TEAM-E T Cells in Recurrent Glioblastoma · Bryan D. Choi · 2024 · 449 citations · Cited by this paper
  30. ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma · Congcong Zhang · 2015 · 394 citations · Cited by this paper
  31. HER2-Specific T Cells Target Primary Glioblastoma Stem Cells and Induce Regression of Autologous Experimental Tumors · Nabil M. Ahmed · 2010 · 388 citations · Cited by this paper
  32. Focused ultrasound-mediated drug delivery through the blood–brain barrier · Alison Burgess · 2015 · 329 citations · Cited by this paper
  33. IN VIVO CELL ACTIVATION FOLLOWING OKT3 ADMINISTRATION · Lucienne Chatenoud · 1990 · 327 citations · Cited by this paper
  34. Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants · Giedre Krenciute · 2017 · 320 citations · Cited by this paper
  35. RNA Interference Targeting Transforming Growth Factor-β Enhances NKG2D-Mediated Antiglioma Immune Response, Inhibits Glioma Cell Migration and Invasiveness, and Abrogates Tumorigenicity In vivo · Manuel Alexander Friese · 2004 · 303 citations · Cited by this paper
  36. World Health Organization 2021 Classification of Central Nervous System Tumors and Implications for Therapy for Adult-Type Gliomas · Tamar R. Berger · 2022 · 295 citations · Cited by this paper
  37. Regulatable gene expression systems for gene therapy applications: progress and future challenges · Shyam Goverdhana · 2005 · 284 citations · Cited by this paper
  38. Immunohistochemical Detection of EGFRvIII in High Malignancy Grade Astrocytomas and Evaluation of Prognostic Significance · Kenneth Aldape · 2004 · 281 citations · Cited by this paper
  39. In Vitro Characterization of Five Humanized OKT3 Effector Function Variant Antibodies · Danlin Xu · 2000 · 246 citations · Cited by this paper

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