Research map: Distinct contributions of mu opioid and CB2 cannabinoid receptors to neuroimmune and behavioral responses

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  1. Human brain mechanisms of pain perception and regulation in health and disease · A. Vania Apkarian · 2005 · 3167 citations · Cited by this paper
  2. CB1 Cannabinoid Receptor is a Target for Neuroprotection in Light Induced Retinal Degeneration · 2022 · Related
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  8. Methadone alters the peripheral inflammatory and central immune landscape following prenatal exposure in rats · 2022 · Related
  9. Synergistic interactions between cannabinoid and opioid analgesics · Diana L. Cichewicz · 2003 · 308 citations · Cited by this paper
  10. Alcohol induced behavioral and immune perturbations are attenuated by activation of CB2 cannabinoid receptors · 2023 · Related
  11. A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice · Donal Skelly · 2013 · 280 citations · Cited by this paper
  12. Advances in DNA, histone, and RNA methylation mechanisms in the pathophysiology of alcohol use disorder · 2023 · Related
  13. Brain Neuronal CB2 Cannabinoid Receptors in Drug Abuse and Depression: From Mice to Human Subjects · Emmanuel Shan Onaivi · 2008 · 260 citations · Cited by this paper
  14. Factors associated with perinatal substance use among Ethiopian women: an institutional-based cross-sectional study · 2023 · Related
  15. CXCL10 (IFN-γ-Inducible Protein-10) Control of Encephalitogenic CD4+ T Cell Accumulation in the Central Nervous System During Experimental Autoimmune Encephalomyelitis · Brian T. Fife · 2001 · 257 citations · Cited by this paper
  16. Alcohol Use Disorders and Their Harmful Effects on the Contractility of Skeletal, Cardiac and Smooth Muscles · 2021 · Related
  17. Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice · Laura Bohn · 2002 · 247 citations · Cited by this paper
  18. MicroRNA-mediated translational pathways are regulated in the orbitofrontal cortex and peripheral blood samples during acute abstinence from heroin self-administration · 2023 · Related
  19. Brain circuits for pain and its treatment · Nicole Mercer Lindsay · 2021 · 235 citations · Cited by this paper
  20. Effectiveness of pharmacotherapies for diabetes on nicotine, food, and water intake in insulin-resistant rats · 2024 · Related
  21. Cloning and molecular characterization of the rat CB2 cannabinoid receptor · Sean M. Brown · 2002 · 190 citations · Cited by this paper
  22. Functional Expression of Brain Neuronal CB2 Cannabinoid Receptors Are Involved in the Effects of Drugs of Abuse and in Depression · Emmanuel Shan Onaivi · 2008 · 179 citations · Cited by this paper
  23. Molecular and cellular basis of cannabinoid and opioid interactions · Daniela Viganò · 2005 · 168 citations · Cited by this paper
  24. CB2 Receptor in Microglia: The Guardian of Self-Control · Joanna Agnieszka Komorowska‐Müller · 2020 · 166 citations · Cited by this paper
  25. Postsynaptic localization of CB2 cannabinoid receptors in the rat hippocampus · Alicia Brusco · 2008 · 165 citations · Cited by this paper
  26. Cannabinoid–opioid interactions during neuropathic pain and analgesia · Ittai Bushlin · 2009 · 165 citations · Cited by this paper
  27. Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference · Qing‐Rong Liu · 2017 · 149 citations · Cited by this paper
  28. Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies · Katia Befort · 2015 · 131 citations · Cited by this paper
  29. Microglia, Cytokines, and Neural Activity: Unexpected Interactions in Brain Development and Function · Austin Ferro · 2021 · 125 citations · Cited by this paper
  30. Role of CB2 Cannabinoid Receptors in the Rewarding, Reinforcing, and Physical Effects of Nicotine · Francisco Navarrete · 2013 · 120 citations · Cited by this paper
  31. Interleukin-1β and Interleukin-6 in Arthritis Animal Models: Roles in the Early Phase of Transition from Acute to Chronic Inflammation and Relevance for Human Rheumatoid Arthritis · Gianfranco Ferraccioli · 2010 · 113 citations · Cited by this paper
  32. Development of an assay to measure in vivo cytokine production in the mouse · F D Finkelman · 1999 · 106 citations · Cited by this paper
  33. Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists · Shaness A. Grenald · 2016 · 100 citations · Cited by this paper
  34. Cannabinoid 2 receptor attenuates inflammation during skin wound healing by inhibiting M1 macrophages rather than activating M2 macrophages · Yu Lei Du · 2018 · 94 citations · Cited by this paper
  35. Role of cannabinoid CB2receptor in the reinforcing actions of ethanol · Antonio Ortega-Álvaro · 2013 · 83 citations · Cited by this paper
  36. Spatial transcriptomics reveals the distinct organization of mouse prefrontal cortex and neuronal subtypes regulating chronic pain · Aritra Bhattacherjee · 2023 · 77 citations · Cited by this paper
  37. Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids · Keith M. Olson · 2019 · 56 citations · Cited by this paper
  38. Crosstalk between Mu-Opioid receptors and neuroinflammation: Consequences for drug addiction and pain · Javier Cuitavi · 2022 · 55 citations · Cited by this paper
  39. Different neuronal populations mediate inflammatory pain analgesia by exogenous and endogenous opioids · Xinyan Zhang · 2020 · 54 citations · Cited by this paper

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