Research map: Radiotherapy, inflammation, and the myeloid perspective

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Papers in this map

  1. STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors · Liufu Deng · 2014 · 2194 citations · Cited by this paper
  2. When biomarkers for major depressive disorder remain elusive · 2024 · Related
  3. The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence · Holly E. Barker · 2015 · 2192 citations · Cited by this paper
  4. Gaseous biomarkers speak medical conditions · 2026 · Related
  5. DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity · Claire Vanpouille‐Box · 2017 · 1828 citations · Cited by this paper
  6. Unfolding ecDNA as a pan-cancer therapeutic target · 2025 · Related
  7. cGAS surveillance of micronuclei links genome instability to innate immunity · Karen J. Mackenzie · 2017 · 1798 citations · Cited by this paper
  8. The AI doctor will see you soon: from assistants to autonomous practitioners · 2025 · Related
  9. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy · Eric A. Reits · 2006 · 1749 citations · Cited by this paper
  10. Target discovery-directed pharmacological mechanism elucidation of bioactive natural products · 2025 · Related
  11. Mitotic progression following DNA damage enables pattern recognition within micronuclei · Shane M. Harding · 2017 · 1531 citations · Cited by this paper
  12. Severe trauma care: advances and future directions in diagnostic and therapeutic techniques and information technology support · 2026 · Related
  13. Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment · Youjin Lee · 2009 · 1335 citations · Cited by this paper
  14. Artificial intelligence-based software as a medical device: regulatory evolution toward continuous oversight · 2026 · Related
  15. Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy · Felix Klug · 2013 · 1109 citations · Cited by this paper
  16. Proactive personalized early warning systems: the next frontier in climate–health preparedness · 2026 · Related
  17. Radiotherapy and immunotherapy: a beneficial liaison? · Ralph R. Weichselbaum · 2017 · 1095 citations · Cited by this paper
  18. Transfer RNA-derived small RNAs (tsRNAs) in Alzheimer’s disease: emerging mechanisms and diagnostic potential · 2026 · Related
  19. Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors · Benjamin J. Moeller · 2004 · 993 citations · Cited by this paper
  20. Myeloid-Derived Suppressor Cells and Radiotherapy: Regulation and Clinical Implications · 2026 · Related
  21. The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon–Dependent Innate and Adaptive Immunity · Byron Burnette · 2011 · 883 citations · Cited by this paper
  22. Effects of Ionizing Radiation on Biological Molecules—Mechanisms of Damage and Emerging Methods of Detection · Julie A. Reisz · 2014 · 836 citations · Cited by this paper
  23. Opportunities and challenges of radiotherapy for treating cancer · Dörthe Schaue · 2015 · 790 citations · Cited by this paper
  24. TGFβ Is a Master Regulator of Radiation Therapy-Induced Antitumor Immunity · Claire Vanpouille‐Box · 2015 · 515 citations · Cited by this paper
  25. Host STING-dependent MDSC mobilization drives extrinsic radiation resistance · Hua Laura Liang · 2017 · 498 citations · Cited by this paper
  26. Cytokines in Radiobiological Responses: A Review · Dörthe Schaue · 2012 · 410 citations · Cited by this paper
  27. CD39/CD73/A2AR pathway and cancer immunotherapy · Chenglai Xia · 2023 · 399 citations · Cited by this paper
  28. The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury · Bo Hu · 2016 · 382 citations · Cited by this paper
  29. Cutting Edge: Activation of STING in T Cells Induces Type I IFN Responses and Cell Death · Bridget M. Larkin · 2017 · 368 citations · Cited by this paper
  30. STING-induced regulatory B cells compromise NK function in cancer immunity · Sirui Li · 2022 · 345 citations · Cited by this paper
  31. Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment · Xue‐Yan He · 2024 · 292 citations · Cited by this paper
  32. Portrait of inflammatory response to ionizing radiation treatment · Federica Maria Di Maggio · 2015 · 290 citations · Cited by this paper
  33. The 5Rs of Radiobiology · G. Gordon Steel · 1989 · 285 citations · Cited by this paper
  34. Non-canonical NF-κB Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy · Yuzhu Hou · 2018 · 278 citations · Cited by this paper
  35. YTHDF2 inhibition potentiates radiotherapy antitumor efficacy · Liangliang Wang · 2023 · 262 citations · Cited by this paper
  36. Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration · Kaiting Yang · 2022 · 222 citations · Cited by this paper
  37. Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization · Jason H. Stafford · 2015 · 220 citations · Cited by this paper
  38. Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment · Yuki Muroyama · 2017 · 220 citations · Cited by this paper
  39. Ionizing radiation modulates human macrophages towards a pro-inflammatory phenotype preserving their pro-invasive and pro-angiogenic capacities · Ana Teresa Pinto · 2016 · 217 citations · Cited by this paper

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