Research map: Esketamine alleviates neuroinflammation and cognitive impairment in male 3xTg-AD mice by regulating the TAOK1/IL-17 axis

Back to the article

Papers in this map

  1. The IL-17 family in diseases: from bench to bedside · Longjie Huangfu · 2023 · 459 citations · Cited by this paper
  2. Interplay between cardiomyocytes and nonmyocytes plays a vital role in cardiac metabolism and function: early-phase metabolic syndrome and short QT · 2025 · Related
  3. Alzheimer’s disease: insights into pathology, molecular mechanisms, and therapy · Qiuyang Zheng · 2024 · 398 citations · Cited by this paper
  4. Association of stromal cell-derived factor 1α and interferon-γ-induced protein 10 with Fontan pathophysiology · 2026 · Related
  5. Mechanisms of sex differences in Alzheimer’s disease · Chloe Lopez-Lee · 2024 · 369 citations · Cited by this paper
  6. Cost-effectiveness of incretin therapies: a Canadian lens on diabetes, obesity, and emerging indications · 2026 · Related
  7. Early neuronal accumulation of DNA double strand breaks in Alzheimer’s disease · Niraj M. Shanbhag · 2019 · 228 citations · Cited by this paper
  8. Protective effects of Melissa officinalis ethanolic extract on doxorubicin-induced cardiotoxicity in a rat model · 2025 · Related
  9. IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease · Helena C. Brigas · 2021 · 227 citations · Cited by this paper
  10. Placental hypoxia and oxidative stress responses to smokeless tobacco use in Alaska Native participants in the MAW study · 2026 · Related
  11. Esketamine Nasal Spray versus Quetiapine for Treatment-Resistant Depression · Andreas Reif · 2023 · 219 citations · Cited by this paper
  12. Variability in agitated saline echocardiography protocols: a cross-sectional analysis of bubble study techniques in echo labs across Alberta, Canada · 2026 · Related
  13. Updates in Alzheimer's disease: from basic research to diagnosis and therapies · Enjie Liu · 2024 · 194 citations · Cited by this paper
  14. Redox homeostasis and therapeutic modulation: the central role of oxidative stress and nuclear factor erythroid 2-related factor 2 (Nrf2) activation in systemic diseases and reproductive dysfunction · 2025 · Related
  15. Alzheimer’s Disease: Exploring the Landscape of Cognitive Decline · Rumiana Tenchov · 2024 · 155 citations · Cited by this paper
  16. The transplacental transfer of NHC, the active metabolite of molnupiravir, in the ex vivo human placental perfusion model · 2026 · Related
  17. Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration · Vishnu Dileep · 2023 · 136 citations · Cited by this paper
  18. THE ASSOCIATION OF ARTERIAL STIFFNESS WITH THE HIGH INCIDENCE OF CARDIAC ARRHYTHMIAS IN PATIENTS WITH PERIPHERAL ARTERIAL DISEASE · 2026 · Related
  19. Contributions of DNA Damage to Alzheimer’s Disease · Xiaozeng Lin · 2020 · 119 citations · Cited by this paper
  20. Neuroprotective Effects of Esketamine in Central Nervous System Disorders: Mechanisms and Cellular Targets · 2026 · Related
  21. IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway · Ting Liu · 2019 · 87 citations · Cited by this paper
  22. The Diverse Roles of TAO Kinases in Health and Diseases · Chih‐Yeu Fang · 2020 · 83 citations · Cited by this paper
  23. Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models · Oliver Wirths · 2020 · 74 citations · Cited by this paper
  24. TAOK1 is associated with neurodevelopmental disorder and essential for neuronal maturation and cortical development · Geeske M. van Woerden · 2021 · 67 citations · Cited by this paper
  25. Esketamine Prevents Postoperative Emotional and Cognitive Dysfunction by Suppressing Microglial M1 Polarization and Regulating the BDNF-TrkB Pathway in Ageing Rats with Preoperative Sleep Disturbance · Yuxin Wen · 2024 · 62 citations · Cited by this paper
  26. Early oxidative stress and DNA damage in Aβ-burdened hippocampal neurons in an Alzheimer’s-like transgenic rat model · Morgan K. Foret · 2024 · 61 citations · Cited by this paper
  27. Ketamine, Esketamine, and Arketamine: Their Mechanisms of Action and Applications in the Treatment of Depression and Alleviation of Depressive Symptoms · Piotr Kawczak · 2024 · 56 citations · Cited by this paper
  28. De Novo Variants in TAOK1 Cause Neurodevelopmental Disorders · Marija Dulovic‐Mahlow · 2019 · 50 citations · Cited by this paper
  29. Interleukin-17 (IL-17) triggers systemic inflammation, peripheral vascular dysfunction, and related prothrombotic state in a mouse model of Alzheimer's disease · Valentina Vellecco · 2022 · 46 citations · Cited by this paper
  30. TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration · Ryo Endo · 2018 · 35 citations · Cited by this paper
  31. Therapeutic potential of targeting IL-17 and its receptor signaling in neuroinflammation · Avtar Singh Gautam · 2023 · 34 citations · Cited by this paper
  32. Esketamine vs. placebo combined with erector spinae plane block vs. intercostal nerve block on quality of recovery following thoracoscopic lung resection: a randomized controlled factorial trial · Jing-Hui Hu · 2024 · 24 citations · Cited by this paper
  33. A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission · Mikhail A. Liskovykh · 2019 · 22 citations · Cited by this paper
  34. Thousand and one kinase 1 protects MCAO-induced cerebral ischemic stroke in rats by decreasing apoptosis and pro-inflammatory factors · Jiahui Li · 2019 · 21 citations · Cited by this paper
  35. Neurodevelopmental disorder–associated mutations in TAOK1 reveal its function as a plasma membrane remodeling kinase · Neal Beeman · 2023 · 21 citations · Cited by this paper
  36. Icariin alleviates cognitive dysfunction by reducing neuroinflammation via the cGAS-STING pathway · Fengjuan Lu · 2025 · 21 citations · Cited by this paper
  37. Biomass fuel induces neuroinflammation and neurodegeneration via the astrocyte-microglia IL-17A/IL-17RA pathway · Fengchu Liang · 2025 · 19 citations · Cited by this paper
  38. Hypothermia Reduces but Hyperthermia Augments T Cell-Derived Release of Interleukin-17 and Granzyme B that Mediate Neuronal Cell Death · Tomohiro Matsui · 2014 · 16 citations · Cited by this paper
  39. Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation · Hui Li · 2024 · 16 citations · Cited by this paper

Source: OpenAlex (CC0)