Research map: Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation
Back to the article
Papers in this map
- Protective and pathogenic functions of macrophage subsets · Peter J. Murray · 2011 · 5341 citations · Cited by this paper
- Regulation of macrophage polarization in chronic airway inflammatory diseases: immune interactions, metabolic reprogramming, and beyond · Hongyang Zhang · 2026 · Cites this paper
- Macrophage CCRL2 promotes NLRP3 inflammasome activation to exacerbate atherosclerosis · 2026 · Related
- Alternative Activation of Macrophages: Mechanism and Functions · Siamon Gordon · 2010 · 4258 citations · Cited by this paper
- Mechanistic impasses: tofacitinib treatment ameliorates GM-CSF-driven macrophage inflammation · 2026 · Related
- Platelets and the immune continuum · John W. Semple · 2011 · 1713 citations · Cited by this paper
- Melanosomes support immune evasion in melanoma · 2026 · Related
- Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials · Claus Bachert · 2019 · 1566 citations · Cited by this paper
- T cell adaptation in chronic infections and tumors · 2026 · Related
- Macrophage-mediated inflammation in metabolic disease · Ajay Chawla · 2011 · 1334 citations · Cited by this paper
- Cathepsin C orchestrates RSV-induced asthma exacerbation through the dual effect of monocyte-derived macrophages · 2026 · Related
- CD36, a Scavenger Receptor Involved in Immunity, Metabolism, Angiogenesis, and Behavior · Roy L. Silverstein · 2009 · 1281 citations · Cited by this paper
- Lytic IFNγ is stored in cytotoxic granules and coreleased with granzyme B to mediate cytotoxic T lymphocyte killing · 2026 · Related
- EPOS2020: A Major Step Forward · Wytske Johanna Fokkens · 2020 · 1237 citations · Cited by this paper
- Defining the rules of engagement: B cells, antibodies and cancer control · 2026 · Related
- Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease · Steven J. Van Dyken · 2013 · 733 citations · Cited by this paper
- Vimentin trogocytosis as a novel mechanism of NK cell exhaustion by circulating tumor cells · 2026 · Related
- Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation · Stanley Ching‐Cheng Huang · 2016 · 703 citations · Cited by this paper
- TWEAK receptor (Fn14) exacerbates TNF-α-induced inflammation in rheumatoid arthritis synovial fibroblasts and influences response to anti-TNF-α therapy · 2026 · Related
- Alternative Macrophage Activation and Metabolism · Justin Iver Odegaard · 2011 · 650 citations · Cited by this paper
- The Parkinson’s disease-linked G2019S mutation of LRRK2 increases NADPH oxidase-2 activity in neutrophils for superior control of bacterial infections · 2026 · Related
- Mepolizumab for chronic rhinosinusitis with nasal polyps (SYNAPSE): a randomised, double-blind, placebo-controlled, phase 3 trial · Joseph K. Han · 2021 · 628 citations · Cited by this paper
- Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences · Fernando O. Martínez · 2013 · 512 citations · Cited by this paper
- Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 · Lorna A. Farrelly · 2019 · 499 citations · Cited by this paper
- CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate · Yiliang Chen · 2022 · 475 citations · Cited by this paper
- Krebs Cycle Reborn in Macrophage Immunometabolism · Dylan G. Ryan · 2020 · 453 citations · Cited by this paper
- High IFN-γ and low SLPI mark severe asthma in mice and humans · Mahesh Ramdas Raundhal · 2015 · 411 citations · Cited by this paper
- The role of serotonin and its receptors in activation of immune responses and inflammation · Mohammad Sharif Shajib · 2014 · 366 citations · Cited by this paper
- Platelet Physiology · Andrew L. Frelinger · 2016 · 345 citations · Cited by this paper
- Type 2 immunity in allergic diseases · İsmail Öğülür · 2025 · 345 citations · Cited by this paper
- Serotonin a la carte: Supplementation with the serotonin precursor 5-hydroxytryptophan · Erick H. Turner · 2005 · 330 citations · Cited by this paper
- Enterochromaffin 5-HT cells – A major target for GLP-1 and gut microbial metabolites · Mari Lilith Lund · 2018 · 263 citations · Cited by this paper
- Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation · Simon C. Pitchford · 2004 · 231 citations · Cited by this paper
- 2023 GINA report for asthma · Priya Venkatesan · 2023 · 210 citations · Cited by this paper
- Transglutaminase 2 inhibitors and their therapeutic role in disease states · Mathew Siegel · 2007 · 209 citations · Cited by this paper
- (–)‐Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle · Leonardo Nogueira · 2011 · 205 citations · Cited by this paper
- Tezepelumab in Adults with Severe Chronic Rhinosinusitis with Nasal Polyps · Brian Jonathon Lipworth · 2025 · 204 citations · Cited by this paper
- Chronic Rhinosinusitis with Nasal Polyps · Claire Hopkins · 2019 · 197 citations · Cited by this paper
- Role of serotonin receptor signaling in cancer cells and anti-tumor immunity · Surojit Karmakar · 2021 · 195 citations · Cited by this paper
Source: OpenAlex (CC0)