Research map: Fc-Silenced CD89 × EGFR Bispecific Antibodies Promote Neutrophil and Macrophage Antitumor Activity

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  1. Targeting M2-like tumor-associated macrophages is a potential therapeutic approach to overcome antitumor drug resistance · Shujing Wang · 2024 · 563 citations · Cited by this paper
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  24. An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo · Stefan Lohse · 2015 · 76 citations · Cited by this paper
  25. Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding · M. Jack Borrok · 2015 · 72 citations · Cited by this paper
  26. Expression and Modulation of the Human Immunoglobulin A Fc Receptor (CD89) and the FcR γ Chain on Myeloid Cells in Blood and Tissue · R Hamre · 2003 · 64 citations · Cited by this paper
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  28. Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting · Saskia Meyer · 2015 · 55 citations · Cited by this paper
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  30. Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors · G Hale · 2024 · 34 citations · Cited by this paper
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  33. Targeting CD89 on tumor-associated macrophages overcomes resistance to immune checkpoint blockade · Lijun Xu · 2022 · 17 citations · Cited by this paper
  34. Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor · Wenpeng Cai · 2025 · 16 citations · Cited by this paper
  35. Neutrophil CD16b crosslinking induces lipid raft-mediated activation of SHP-2 and affects cytokine expression and retarded neutrophil apoptosis · Hao Yang · 2017 · 13 citations · Cited by this paper
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