Research map: Interleukin-2 is associated with cytopenias in systemic lupus erythematosus

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Papers in this map

  1. Updating the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus · M.C. Hochberg · 1997 · 11598 citations · Cited by this paper
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  3. The development and initial validation of the systemic lupus international collaborating clinics/American college of rheumatology damage index for systemic lupus erythematosus · Dafna D. Gladman · 1996 · 2609 citations · Cited by this paper
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  5. Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene · Benjamin Sadlack · 1993 · 1763 citations · Cited by this paper
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  7. Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy · Wei Liao · 2013 · 1105 citations · Cited by this paper
  8. Significance of glomerular IgG3 deposition in patients with primary membranous nephropathy · 2026 · Related
  9. Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β · Haruhiko Suzuki · 1995 · 870 citations · Cited by this paper
  10. Interferon regulatory factor 1 mediates ROS-dependent release of NETs in LPS-induced mouse pneumonia by interacting with matrix metalloproteinase 9 · 2026 · Related
  11. Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus · Jing He · 2016 · 589 citations · Cited by this paper
  12. Identification of potential diagnostic biomarkers for systemic juvenile idiopathic arthritis by integrative transcriptomic analysis · 2026 · Related
  13. Global Natural Regulatory T Cell Depletion in Active Systemic Lupus Erythematosus · Makoto Miyara · 2005 · 459 citations · Cited by this paper
  14. IDO1-mediated M2 macrophage polarization alleviates the progression of ankylosing spondylitis · 2024 · Related
  15. 2021 DORIS definition of remission in SLE: final recommendations from an international task force · Ronald van Vollenhoven · 2021 · 378 citations · Cited by this paper
  16. Research progress on animal models of autoimmune gastritis · 2026 · Related
  17. Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial · Jing He · 2019 · 351 citations · Cited by this paper
  18. Alteration of telomere length and mtDNA copy number in interstitial lung disease associated with rheumatoid arthritis · 2025 · Related
  19. Interleukin 2: from immunostimulation to immunoregulation and back again · Martin F. Bachmann · 2007 · 310 citations · Cited by this paper
  20. Haematological manifestations of lupus · Anum Fayyaz · 2015 · 298 citations · Cited by this paper
  21. The role of neutrophils in the pathogenesis of systemic lupus erythematosus · Carolyne K. Smith · 2015 · 163 citations · Cited by this paper
  22. The IL-2 Defect in Systemic Lupus Erythematosus Disease Has an Expansive Effect on Host Immunity · Linda A. Lieberman · 2010 · 157 citations · Cited by this paper
  23. Leukopenia, lymphopenia, and neutropenia in systemic lupus erythematosus: Prevalence and clinical impact—A systematic literature review · Linda Carli · 2015 · 138 citations · Cited by this paper
  24. Lupus thrombocytopenia: clinical implications and prognostic significance · Panayiotis D. Ziakas · 2005 · 125 citations · Cited by this paper
  25. Management of immune cytopenias in patients with systemic lupus erythematosus — Old and new · Kam A. Newman · 2013 · 122 citations · Cited by this paper
  26. Defining Low Disease Activity in Systemic Lupus Erythematosus · Ari Polachek · 2016 · 108 citations · Cited by this paper
  27. T-regulatory cells in systemic lupus erythematosus · Antonio La Cava · 2008 · 97 citations · Cited by this paper
  28. A Novel System to Categorize the Symptoms of Systemic Lupus Erythematosus · David S. Pisetsky · 2018 · 85 citations · Cited by this paper
  29. Low dose of IL-2 combined with rapamycin restores and maintains the long-term balance of Th17/Treg cells in refractory SLE patients · Chunmiao Zhao · 2019 · 78 citations · Cited by this paper
  30. Conversion of T Follicular Helper Cells to T Follicular Regulatory Cells by Interleukin‐2 Through Transcriptional Regulation in Systemic Lupus Erythematosus · Hao He · 2020 · 71 citations · Cited by this paper
  31. Regulatory T Cells and Systemic Lupus Erythematosus · Philip A. Mudd · 2006 · 60 citations · Cited by this paper
  32. Correlation between levels of TNF-α and IL-6 and hematological involvement in SLE Egyptian Patients with lupus nephritis · Alaa Abdel-Aziz Sabry · 2007 · 41 citations · Cited by this paper
  33. Low-dose interleukin-2 therapy for the treatment of systemic lupus erythematosus · Jens Y. Humrich · 2018 · 36 citations · Cited by this paper
  34. Cytokine profiles and their correlation with clinical and blood parameters in rheumatoid arthritis and systemic lupus erythematosus · Nancy Paola Duarte-Delgado · 2024 · 33 citations · Cited by this paper
  35. Prevalence and outcome of thrombocytopenia in systemic lupus erythematous: single-centre cohort analysis · Tatiana Costa Pires · 2021 · 30 citations · Cited by this paper
  36. Low-dose interleukin-2 therapy in systemic lupus erythematosus · Antonio La Cava · 2023 · 18 citations · Cited by this paper
  37. T Cells, Interleukin-2 and Systemic Lupus Erythematosus—From Pathophysiology to Therapy · Anselm Mak · 2022 · 13 citations · Cited by this paper
  38. Clinical Assessment of Cytokine Profiles and Haematological Parameters in Patients with Systemic Lupus Erythematosus: A Cross-Sectional Study from Saudi Arabia · Fahad M. Aldakheel · 2023 · 7 citations · Cited by this paper
  39. Serum 3-Nitrotyrosine in the Cardiovascular Disease of Patients with Systemic Lupus Erythematosus · Juan Carlos Quevedo-Abeledo · 2025 · 3 citations · Cited by this paper

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