Research map: Deciphering keloid formation and treatment: insights from mechanobiology

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Papers in this map

  1. Role of YAP/TAZ in mechanotransduction · Sirio Dupont · 2011 · 6157 citations · Cited by this paper
  2. Beyond fibroblast activation: expanding the role of the amphiregulin–epidermal growth factor receptor axis in keloid pathogenesis · Zihao Li · 2026 · Cites this paper
  3. Proteomic Profiling Reveals a Cytokine-Chemokine Axis Involving CXCL10, CD40, and CCL17 in Dermatitis Herpetiformis Pathogenesis and Treatment Response · 2026 · Related
  4. TGF‐β signaling and the fibrotic response · Andrew Leask · 2004 · 2329 citations · Cited by this paper
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  6. Mechanotransduction and extracellular matrix homeostasis · Jay D. Humphrey · 2014 · 2226 citations · Cited by this paper
  7. Increased Efficacy of Daytime Low-dose Oral Minoxidil Dosing for Androgenetic Alopecia: A Retrospective Study · 2026 · Related
  8. Mechanobiology of YAP and TAZ in physiology and disease · Tito Panciera · 2017 · 1493 citations · Cited by this paper
  9. Reduced sensitization over time to parabens 16% mix in North-eastern Italy, 1997-2023 · 2026 · Related
  10. Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix · Pierre‐Jean Wipff · 2007 · 1349 citations · Cited by this paper
  11. O5 Cancer-associated fibroblasts switch from immune-activating towards immune-suppressive function during cutaneous squamous cell carcinoma disease progression · 2026 · Related
  12. Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor β-mediated Epithelial to Mesenchymal Transition and Cell Migration · Andrei V. Bakin · 2000 · 1001 citations · Cited by this paper
  13. The Shield Sign of Carcinoma Hemorrhagiectoides · 2026 · Related
  14. ILK, PINCH and parvin: the tIPP of integrin signalling · Kyle R. Legate · 2005 · 690 citations · Cited by this paper
  15. O8 Ultraviolet radiation reshapes the metabolome of skin commensal bacteria, influencing aryl hydrocarbon receptor signalling and barrier function · 2026 · Related
  16. Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring · Shamik Mascharak · 2021 · 631 citations · Cited by this paper
  17. Comment on ‘Burden and risk of asthma and rhinitis in people with atopic dermatitis: global estimates from a hierarchical Bayesian model’: reply from authors · 2026 · Related
  18. The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship · Boris Hinz · 2015 · 619 citations · Cited by this paper
  19. Single-cell and spatial transcriptomics in skin research: From molecular complexity to clinical translation · 2026 · Related
  20. The immunology of the porcine skin and its value as a model for human skin · Artur Summerfield · 2014 · 560 citations · Cited by this paper
  21. Fibroblast Dynamics in Keloid Pathogenesis: Unraveling Cellular Crosstalk and Novel Therapeutic Targets · 2026 · Related
  22. Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair · Brett A. Shook · 2018 · 533 citations · Cited by this paper
  23. Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling · Victor W Wong · 2011 · 519 citations · Cited by this paper
  24. Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases · Cheng‐Cheng Deng · 2021 · 509 citations · Cited by this paper
  25. Current potential therapeutic strategies targeting the TGF-β/Smad signaling pathway to attenuate keloid and hypertrophic scar formation · Tao� Zhang · 2020 · 443 citations · Cited by this paper
  26. Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial Plasticity · Neil A. Bhowmick · 2001 · 398 citations · Cited by this paper
  27. Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy · Claire Laure Navarro · 2004 · 382 citations · Cited by this paper
  28. The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models · Grace C. Limandjaja · 2020 · 362 citations · Cited by this paper
  29. The Most Current Algorithms for the Treatment and Prevention of Hypertrophic Scars and Keloids: A 2020 Update of the Algorithms Published 10 Years Ago · Rei Ogawa · 2021 · 356 citations · Cited by this paper
  30. Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans · Jonathan C. J. Wei · 2017 · 308 citations · Cited by this paper
  31. The relationship between skin stretching/contraction and pathologic scarring: The important role of mechanical forces in keloid generation · Rei Ogawa · 2012 · 302 citations · Cited by this paper
  32. Histopathological Differential Diagnosis of Keloid and Hypertrophic Scar · Julia Yu‐Yun Lee · 2004 · 286 citations · Cited by this paper
  33. The Single-Molecule Mechanics of the Latent TGF-β1 Complex · Lara Buscemi · 2011 · 264 citations · Cited by this paper
  34. Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation · Leandra A. Barnes · 2017 · 255 citations · Cited by this paper
  35. Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation · Franco Klingberg · 2014 · 223 citations · Cited by this paper
  36. Pushing Back: Wound Mechanotransduction in Repair and Regeneration · Victor W. Wong · 2011 · 222 citations · Cited by this paper
  37. The tension biology of wound healing · Hans I‐Chen Harn · 2017 · 218 citations · Cited by this paper
  38. Pruritus, pain, and small nerve fiber function in keloids: A controlled study · Siong-See Lee · 2004 · 184 citations · Cited by this paper
  39. TGF-β1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21 · Ying Liu · 2016 · 180 citations · Cited by this paper

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