Research map: Clinical landscape of human pluripotent stem cell-derived cardiomyocyte therapy

Back to the article

Papers in this map

  1. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors · Kazutoshi Takahashi · 2007 · 20451 citations · Cited by this paper
  2. Leave No Data Behind: Exploring a new paradigm in oncology with foundation models and large language models · 2026 · Related
  3. Heart Disease and Stroke Statistics—2021 Update · Salim S. Virani · 2021 · 5907 citations · Cited by this paper
  4. Self-sufficient killing of malignant tumors by an engineered cancer-selective gene circuit · 2026 · Related
  5. A Novel Paradigm for Heart Failure With Preserved Ejection Fraction · Walter J. Paulus · 2013 · 3564 citations · Cited by this paper
  6. Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID · 2026 · Related
  7. Global burden of heart failure: a comprehensive and updated review of epidemiology · Gianluigi Savarese · 2022 · 3331 citations · Cited by this paper
  8. Repurposed ethoxzolamide reprograms antitumor immunity through β-TrCP-dependent PD-L1 ubiquitination · 2026 · Related
  9. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts · Michael A. Laflamme · 2007 · 2231 citations · Cited by this paper
  10. Combine antibody-drug conjugate with cmLumiOpto for triple-negative breast cancer treatment · 2026 · Related
  11. Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling · Xiaojun Lance Lian · 2012 · 1797 citations · Cited by this paper
  12. Case of complete response to immunotherapy in MMR-deficient prostate cancer associated with NK-like and CD4+CD8+ T cells · 2026 · Related
  13. Chemically defined generation of human cardiomyocytes · Paul W. Burridge · 2014 · 1676 citations · Cited by this paper
  14. Therapeutic Gfral silencing via antisense oligonucleotides ameliorates cancer-associated cachexia and extends survival in tumor-bearing mice · 2026 · Related
  15. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts · James J.H. Chong · 2014 · 1438 citations · Cited by this paper
  16. Köhlmeier-Degos disease is an interferonopathy characterized by type I and II interferon-driven inflammatory vasculopathy · 2026 · Related
  17. Cardiac Energy Metabolism in Heart Failure · Gary D. Lopaschuk · 2021 · 1412 citations · Cited by this paper
  18. Metabolomic and lifestyle profiles refine BMI-metabolic phenotypes in older adults · 2026 · Related
  19. Temporal trends and patterns in heart failure incidence: a population-based study of 4 million individuals · Nathalie Conrad · 2017 · 1360 citations · Cited by this paper
  20. Alterations of the host-lung microbiome metasystem in systemic inflammatory response syndrome is associated with secondary pneumonia · 2026 · Related
  21. Heart regeneration · Michael A. Laflamme · 2011 · 1233 citations · Cited by this paper
  22. Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines · Steven J. Kattman · 2011 · 1193 citations · Cited by this paper
  23. Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology · Steven J. Forrester · 2018 · 1110 citations · Cited by this paper
  24. Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes · Shugo Tohyama · 2012 · 1104 citations · Cited by this paper
  25. Leukocyte Behavior in Atherosclerosis, Myocardial Infarction, and Heart Failure · Filip K. Świrski · 2013 · 1103 citations · Cited by this paper
  26. A novel recovery system for cultured cells using plasma‐treated polystyrene dishes grafted with poly(N‐isopropylacrylamide) · Teruo Okano · 1993 · 1027 citations · Cited by this paper
  27. Tissue Engineering of a Differentiated Cardiac Muscle Construct · Wolfram‐Hubertus Zimmermann · 2002 · 919 citations · Cited by this paper
  28. Cardiomyocyte Grafting for Cardiac Repair: Graft Cell Death and Anti-Death Strategies · Ming Zhang · 2001 · 889 citations · Cited by this paper
  29. Coronary Microvascular Rarefaction and Myocardial Fibrosis in Heart Failure With Preserved Ejection Fraction · Selma F. Mohammed · 2014 · 875 citations · Cited by this paper
  30. Mechanisms and Models in Heart Failure · Douglas L. Mann · 2005 · 875 citations · Cited by this paper
  31. Allogeneic transplantation of iPS cell-derived cardiomyocytes regenerates primate hearts · Yuji Shiba · 2016 · 864 citations · Cited by this paper
  32. Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine · Elaheh Karbassi · 2020 · 798 citations · Cited by this paper
  33. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts · Yuji Shiba · 2012 · 783 citations · Cited by this paper
  34. Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients · T. Deuse · 2019 · 775 citations · Cited by this paper
  35. Pathological Ventricular Remodeling · Jana S. Burchfield · 2013 · 774 citations · Cited by this paper
  36. Cell Death in the Pathogenesis of Heart Disease: Mechanisms and Significance · Russell S. Whelan · 2010 · 769 citations · Cited by this paper
  37. A mechanistic role for cardiac myocyte apoptosis in heart failure · Detlef Wencker · 2003 · 748 citations · Cited by this paper
  38. The human heart contains distinct macrophage subsets with divergent origins and functions · Geetika Bajpai · 2018 · 720 citations · Cited by this paper
  39. Ca 2+ /Calmodulin–Dependent Protein Kinase Modulates Cardiac Ryanodine Receptor Phosphorylation and Sarcoplasmic Reticulum Ca 2+ Leak in Heart Failure · Xun Ai · 2005 · 700 citations · Cited by this paper

Source: OpenAlex (CC0)