Research map: Beyond Structure: The Dynamic Role of the Extracellular Matrix Components in Immune Evasion
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Papers in this map
The blockade of immune checkpoints in cancer immunotherapy
· Drew M. Pardoll · 2012 · 14056 citations · Cited by this paper
In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high‐throughput personalized drug discovery
· 2025 · Related
Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
· Suzanne Louise Topalian · 2012 · 12851 citations · Cited by this paper
Anbenitamab in combination with chemotherapy in patients with HER2‐positive gastric or gastroesophageal junction carcinoma who failed previous therapy containing trastuzumab: a multicenter, phase II study (KC‐WISE 01)
· 2025 · Related
Oncology Meets Immunology: The Cancer-Immunity Cycle
· Daniel S. Chen · 2013 · 7139 citations · Cited by this paper
A practical overview and statistical analysis of interval‐censored data in cancer
· 2025 · Related
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
· Dung Thi Le · 2017 · 6820 citations · Cited by this paper
Allogeneic double-negative T-cell therapy for acute myeloid leukemia
· 2025 · Related
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
· Robert D. Schreiber · 2011 · 6575 citations · Cited by this paper
The Roles of Protein S -Palmitoylation in Cancers: From Dynamic Modulation to Therapeutic Potential
· 2026 · Related
Role of YAP/TAZ in mechanotransduction
· Sirio Dupont · 2011 · 6157 citations · Cited by this paper
WTAP-Mediated Glutaminase Splicing Bias Suppresses Ferroptosis in Hepatocellular Carcinoma
· 2026 · Related
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
· Shannon L. Maude · 2018 · 5822 citations · Cited by this paper
Proliferation and Apoptosis Adaptor Protein 15 (PEA15), a Potential Oncogenic Regulator of VHL and HIF1A Identified through Proteomic Analysis in Hepatocellular Carcinoma
· 2026 · Related
Mutational heterogeneity in cancer and the search for new cancer-associated genes
· Michael S. Lawrence · 2013 · 5802 citations · Cited by this paper
Tumor-associated fibrosis as a regulator of tumor immunity and response to immunotherapy
· 2017 · Related
Elements of cancer immunity and the cancer–immune set point
· Daniel S. Chen · 2017 · 5536 citations · Cited by this paper
Interactions between cancer-associated fibroblasts and T-cells: functional crosstalk with targeting and biomarker potential
· 2024 · Related
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
· Tyler Jay Curiel · 2004 · 5154 citations · Cited by this paper
ECM formation and degradation during fibrosis, repair, and regeneration
· 2025 · Related
mRNA vaccines — a new era in vaccinology
· Norbert Pardi · 2018 · 4712 citations · Cited by this paper
The extracellular matrix at a glance
· Christian Frantz · 2010 · 4411 citations · Cited by this paper
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
· Karin E. de Visser · 2023 · 4018 citations · Cited by this paper
Collagen Structure and Stability
· Matthew D. Shoulders · 2009 · 3936 citations · Cited by this paper
Integrins in cancer: biological implications and therapeutic opportunities
· Jay S. Desgrosellier · 2009 · 3804 citations · Cited by this paper
Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
· Zachary Rockow Chalmers · 2017 · 3804 citations · Cited by this paper
ATAC‐seq: A Method for Assaying Chromatin Accessibility Genome‐Wide
· Jason Daniel Buenrostro · 2015 · 3742 citations · Cited by this paper
Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma
· Omid Hamid · 2013 · 3430 citations · Cited by this paper
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
· Chih‐Hao Chang · 2015 · 3398 citations · Cited by this paper
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
· Nicholas McGranahan · 2016 · 3184 citations · Cited by this paper
The extracellular matrix: A dynamic niche in cancer progression
· Pengfei Lu · 2012 · 3083 citations · Cited by this paper
The Immunobiology of Cancer Immunosurveillance and Immunoediting
· Gavin P. Dunn · 2004 · 3045 citations · Cited by this paper
Matrix metalloproteinases and the regulation of tissue remodelling
· Andrea Page-McCaw · 2007 · 3036 citations · Cited by this paper
Development of tumor mutation burden as an immunotherapy biomarker: utility for the oncology clinic
· Timothy An-thy Chan · 2018 · 2934 citations · Cited by this paper
CAR-T cell therapy: current limitations and potential strategies
· Robert C. Sterner · 2021 · 2926 citations · Cited by this paper
Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer
· Daniel Öhlund · 2017 · 2631 citations · Cited by this paper
Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers
· Aaron Michael Goodman · 2017 · 2419 citations · Cited by this paper
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives
· Xiaoqi Mao · 2021 · 2408 citations · Cited by this paper
CTLA-4 and PD-1 Pathways
· Elizabeth Iannotti Buchbinder · 2015 · 2376 citations · Cited by this paper
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