Research map: Differences between men and women in guideline-directed medical therapy implementation, tolerability, and outcomes in heart failure with reduced ejection fraction

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Papers in this map

  1. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure · Theresa A. McDonagh · 2021 · 13611 citations · Cited by this paper
  2. The Yentl syndrome revisited: under-diagnosis and under-treatment in women with wild-type amyloid transthyretin cardiomyopathy · 2026 · Related
  3. 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure · Theresa A. McDonagh · 2023 · 2438 citations · Cited by this paper
  4. Beyond 10-year cardiovascular risk: from event prediction to lifetime disease prevention · 2026 · Related
  5. Predicting survival in heart failure: a risk score based on 39 372 patients from 30 studies · Stuart Pocock · 2012 · 1368 citations · Cited by this paper
  6. Evidence saves lives only when it is implemented · 2026 · Related
  7. Medical Therapy for Heart Failure With Reduced Ejection Fraction · Stephen John Greene · 2018 · 1323 citations · Cited by this paper
  8. Heart failure guideline-directed medical therapy in young adults with dystrophin-related cardiomyopathy: the HOPE-MD registry · 2026 · Related
  9. Epidemiology and One-Year Outcomes in Patients With Chronic Heart Failure and Preserved, Mid-Range and Reduced Ejection Fraction: An Analysis of The ESC Heart Failure Long-Term Registry · Ovidiu Chioncel · 2017 · 927 citations · Cited by this paper
  10. Regional and socioeconomic disparities in the diagnosis of primary electrical diseases in a universal healthcare system: a nationwide Danish study · 2026 · Related
  11. Sex differences in pharmacokinetics predict adverse drug reactions in women · Irving Zucker · 2020 · 813 citations · Cited by this paper
  12. Physician–patient sex dyads and management of dyslipidaemia and hypertension in primary care: findings from two population-based studies · 2026 · Related
  13. Sex-Related Differences in Myocardial Remodeling · Maddalena Piro · 2010 · 330 citations · Cited by this paper
  14. Delay and Attrition in Severe Aortic Stenosis: A Four-Checkpoint Systematic Review of Pathway Bottlenecks and Interventions · 2026 · Related
  15. Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational, cohort study · Bernadet T. Santema · 2019 · 259 citations · Cited by this paper
  16. The importance of the urinary albumin/creatinine ratio in contemporary clinical practice: the key we have in our pocket and forget to use · 2026 · Related
  17. Sex-Based Differences in Heart Failure Across the Ejection Fraction Spectrum · Davide Stolfo · 2019 · 219 citations · Cited by this paper
  18. Advanced maternal age at first delivery: an early window into cardiovascular vulnerability · 2026 · Related
  19. Gender and Survival in Patients with Heart Failure: Interactions with Diabetes and Aetiology. Results from the MAGGIC Individual Patient Meta-Analysis · Manuel Martínez‐Sellés · 2012 · 208 citations · Cited by this paper
  20. Temporal changes in guideline-directed medical therapy score and clinical outcomes in patients with heart failure · 2026 · Related
  21. Increasing Participation of Women in Cardiovascular Trials · Leslie Cho · 2021 · 150 citations · Cited by this paper
  22. Association Between Enrolment in a Heart Failure Quality Registry and Subsequent Mortality—A Nationwide Cohort Study · Lars H. Lund · 2017 · 144 citations · Cited by this paper
  23. Sex- and Age-Related Differences in the Management and Outcomes of Chronic Heart Failure: An Analysis of Patients from the ESC HFA EORP Heart Failure Long-Term Registry · Mitja Lainščak · 2019 · 137 citations · Cited by this paper
  24. Adverse Drug Reactions to Guideline-Recommended Heart Failure Drugs in Women · Sophie H. Bots · 2019 · 78 citations · Cited by this paper
  25. Sex Disparities in Longitudinal Use and Intensification of Guideline-Directed Medical Therapy Among Patients With Newly Diagnosed Heart Failure With Reduced Ejection Fraction · Andrew Sumarsono · 2024 · 69 citations · Cited by this paper
  26. Contemporary Guideline-Directed Medical Therapy in De Novo, Chronic, and Worsening Heart Failure Patients: First Data from the TITRATE-HF Study · Jishnu Malgie · 2024 · 68 citations · Cited by this paper
  27. Optimization of Evidence-Based Heart Failure Medications After an Acute Heart Failure Admission · Gad Cotter · 2023 · 67 citations · Cited by this paper
  28. Effect of Sex on Reverse Remodeling in Chronic Systolic Heart Failure · Alberto Aimo · 2017 · 46 citations · Cited by this paper
  29. Sex Differences in Long-Term Outcomes Following Acute Heart Failure Hospitalization: Findings from the Get with the Guidelines-Heart Failure Registry · Neil Keshvani · 2023 · 45 citations · Cited by this paper
  30. Comparative Effectiveness of Dosing of Medical Therapy for Heart Failure: From the CHAMP-HF Registry · Stephen John Greene · 2021 · 40 citations · Cited by this paper
  31. Women With Heart Failure · Mary Norine Walsh · 2019 · 30 citations · Cited by this paper
  32. Global Variations According to Sex in Patients Hospitalized for Heart Failure in the REPORT-HF Registry · Jasper Tromp · 2023 · 28 citations · Cited by this paper
  33. The Different Risk of New-Onset, Chronic, Worsening, and Advanced Heart Failure: A Systematic Review and Meta-Regression Analysis · Abdul Shakoor · 2023 · 17 citations · Cited by this paper
  34. Global real-world data on heart failure with reduced ejection fraction: challenges in optimization and sex disparities · Andrea F. Attanasio · 2025 · 17 citations · Cited by this paper
  35. Sex Differences in the Prognostic Role of Achieving Target Doses of Heart Failure Medications: Data from the Swedish Heart Failure Registry · Amerigo Ferrari · 2024 · 15 citations · Cited by this paper
  36. Female Gender Is Associated with an Increased Left Ventricular Ejection Fraction Recovery in Patients with Heart Failure with Reduced Ejection Fraction · Jakrin Kewcharoen · 2022 · 13 citations · Cited by this paper
  37. Guideline Implementation, Drug Sequencing, and Quality of Care in Heart Failure: Design and Rationale of TITRATE-HF · Pascal R.D. Clephas · 2023 · 13 citations · Cited by this paper
  38. Sex-Based Differences in Heart Failure Management and Outcomes: Insights from the French-DataHF Cohort · Guillaume Baudry · 2025 · 9 citations · Cited by this paper
  39. Real-Life Implementation of Guideline-Recommended Medical Therapy in Heart Failure with Reduced Ejection Fraction: Effects on Prognosis and Left Ventricular Ejection Fraction. Primary results of TITRATE-HF · Jishnu Malgie · 2025 · 4 citations · Cited by this paper

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