Research map: Erosive gout: update on mechanisms, impact and treatment

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  1. 2016 updated EULAR evidence-based recommendations for the management of gout · Pascal Richette · 2016 · 1715 citations · Cited by this paper
  2. Decoding vascular dysfunction in systemic sclerosis: from endothelial damage to clinical implications · 2025 · Related
  3. Osteopontin--a possible anchor of osteoclasts to bone. · Finn P. Reinholt · 1990 · 830 citations · Cited by this paper
  4. Environmental and occupational contributors to autoimmune, inflammatory, and musculoskeletal rheumatic disease: a review of emerging evidence and clinical implications · 2025 · Related
  5. 2020 American College of Rheumatology Guideline for the Management of Gout · John D. FitzGerald · 2020 · 822 citations · Cited by this paper
  6. Unraveling the relationship between disordered sleep and systemic sclerosis outcomes · 2025 · Related
  7. Cellular characterization of the gouty tophus: A quantitative analysis · Nicola Dalbeth · 2010 · 268 citations · Cited by this paper
  8. Fueling fibrosis: metabolic dysregulation in systemic sclerosis · 2025 · Related
  9. Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography · Nicola Dalbeth · 2008 · 208 citations · Cited by this paper
  10. Cholinergic anti-inflammatory pathway and vagus nerve stimulation in rheumatoid arthritis · 2026 · Related
  11. Nuclear Factor-inducing Kinase Plays a Crucial Role in Osteopontin-induced MAPK/IκBα Kinase-dependent Nuclear Factor κB-mediated Promatrix Metalloproteinase-9 Activation · Hema Rangaswami · 2004 · 173 citations · Cited by this paper
  12. Digital monitoring in rheumatoid arthritis: remote assessment, wearables, and data-driven disease management · 2026 · Related
  13. Enhanced osteoclastogenesis in patients with tophaceous gout: Urate crystals promote osteoclast development through interactions with stromal cells · Nicola Dalbeth · 2008 · 156 citations · Cited by this paper
  14. Updates in juvenile dermatomyositis: pathogenesis and therapy · 2025 · Related
  15. Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout · David Bursill · 2019 · 124 citations · Cited by this paper
  16. Decoding VEXAS syndrome: emerging insights into pathogenesis and clinical management · 2025 · Related
  17. Effects of Allopurinol Dose Escalation on Bone Erosion and Urate Volume in Gout: A Dual‐Energy Computed Tomography Imaging Study Within a Randomized, Controlled Trial · Nicola Dalbeth · 2019 · 106 citations · Cited by this paper
  18. Advances in the use of Janus kinase inhibitors · 2026 · Related
  19. Validation of a radiographic damage index in chronic gout · Nicola Dalbeth · 2007 · 98 citations · Cited by this paper
  20. Effects of Febuxostat in Early Gout · Nicola Dalbeth · 2017 · 93 citations · Cited by this paper
  21. 2023 EULAR recommendations on imaging in diagnosis and management of crystal-induced arthropathies in clinical practice · Péter Mandl · 2024 · 87 citations · Cited by this paper
  22. Ultrasound as an Outcome Measure in Gout. A Validation Process by the OMERACT Ultrasound Working Group · Lene Terslev · 2015 · 65 citations · Cited by this paper
  23. Exploratory Study of Radiographic Change in Patients With Tophaceous Gout Treated With Intensive Urate‐Lowering Therapy · Nicola Dalbeth · 2013 · 51 citations · Cited by this paper
  24. Development of a computed tomography method of scoring bone erosion in patients with gout: validation and clinical implications · Nicola Dalbeth · 2010 · 50 citations · Cited by this paper
  25. Urate crystal deposition and bone erosion in gout: ‘inside-out’ or ‘outside-in’? A dual-energy computed tomography study · Patapong Towiwat · 2016 · 44 citations · Cited by this paper
  26. Intensive Serum Urate Lowering With Oral Urate‐Lowering Therapy for Erosive Gout: A Randomized Double‐Blind Controlled Trial · Nicola Dalbeth · 2021 · 39 citations · Cited by this paper
  27. Comparison of phenotype expression by mononuclear phagocytes within subcutaneous gouty tophi and rheumatoid nodules · D. G. Palmer · 1987 · 33 citations · Cited by this paper
  28. Zoledronate for prevention of bone erosion in tophaceous gout: a randomised, double-blind, placebo-controlled trial · Nicola Dalbeth · 2014 · 28 citations · Cited by this paper
  29. Relationship between serum urate and changes in dual-energy CT monosodium urate crystal volume over 1 year in people with gout: an individual participant data analysis · Brooke Kelly · 2024 · 18 citations · Cited by this paper
  30. A Detailed Analysis of the Association between Urate Deposition and Erosions and Osteophytes in Gout · Caroline Pecherstorfer · 2020 · 16 citations · Cited by this paper
  31. Monosodium urate crystal depletion and bone erosion remodeling during pegloticase treatment in patients with uncontrolled gout: Exploratory dual-energy computed tomography findings from MIRROR RCT · Nicola Dalbeth · 2024 · 15 citations · Cited by this paper
  32. Baseline Dual‐Energy Computed Tomography Urate Volume Predicts Fulfillment of Gout Remission After Two Years of Urate‐Lowering Therapy · Adwoa Dansoa Tabi‐Amponsah · 2024 · 12 citations · Cited by this paper
  33. The Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) definition of clinical remission in gout · Adwoa Dansoa Tabi‐Amponsah · 2025 · 12 citations · Cited by this paper
  34. Deconstruction of tophi and synovium defines SPP1+ macrophages involved in extracellular matrix remodelling in gout · Hanlin Xu · 2025 · 12 citations · Cited by this paper
  35. The shrinking toe sign in gout · Thomas Bardin · 2022 · 9 citations · Cited by this paper
  36. Clinical significance of microRNA-328-3p and bone metabolism biomarkers in gout patients with different musculoskeletal ultrasonography imaging · Qingqing Song · 2025 · 7 citations · Cited by this paper
  37. Radiographic damage scores predict grip strength in patients with tophaceous gout · Sarah E. Stewart · 2019 · 6 citations · Cited by this paper
  38. Denosumab did not improve computerized tomography erosion scores when added to intensive urate-lowering therapy in gout: Results from a pilot randomized controlled trial · Angelo Gaffo · 2021 · 4 citations · Cited by this paper
  39. Mapping MSU crystal deposition within MTP joints in tophaceous gout: a dual-energy CT study · Chamaya De Silva · 2025 · 4 citations · Cited by this paper

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