Research map: tRNA ‐Derived Small RNAs in Digestive Cancers: From Translational Regulation to Immune and Extracellular Communication

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  1. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines · Clotilde Théry · 2018 · 11543 citations · Cited by this paper
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  9. A transfer-RNA-derived small RNA regulates ribosome biogenesis · Hak Kyun Kim · 2017 · 652 citations · Cited by this paper
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  11. ARM-seq: AlkB-facilitated RNA methylation sequencing reveals a complex landscape of modified tRNA fragments · Aaron E. Cozen · 2015 · 515 citations · Cited by this paper
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  13. Transfer RNA demethylase ALKBH3 promotes cancer progression via induction of tRNA-derived small RNAs · Zhuojia Chen · 2018 · 374 citations · Cited by this paper
  14. Bile‐Derived Exosomal miR ‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer · 2026 · Related
  15. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression · Shawn M. Lyons · 2016 · 266 citations · Cited by this paper
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  17. MINTbase v2.0: a comprehensive database for tRNA-derived fragments that includes nuclear and mitochondrial fragments from all The Cancer Genome Atlas projects · Venetia Pliatsika · 2017 · 232 citations · Cited by this paper
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  19. Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies · Aristeidis G. Telonis · 2015 · 202 citations · Cited by this paper
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  21. MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data · Phillipe Loher · 2017 · 197 citations · Cited by this paper
  22. Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C · Sara R. Selitsky · 2015 · 146 citations · Cited by this paper
  23. tRNA-Derived Small RNAs: Biogenesis, Modification, Function and Potential Impact on Human Disease Development · Vera Oberbauer · 2018 · 126 citations · Cited by this paper
  24. A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice · Hak Kyun Kim · 2019 · 123 citations · Cited by this paper
  25. Bile acid dysregulation, gut dysbiosis, and gastrointestinal cancer · Jessica Tsuei · 2014 · 118 citations · Cited by this paper
  26. Bias in RNA‐seq Library Preparation: Current Challenges and Solutions · Huajuan Shi · 2021 · 115 citations · Cited by this paper
  27. The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health · Mridusmita Saikia · 2015 · 97 citations · Cited by this paper
  28. tRNA-derived small RNAs: Mechanisms and potential roles in cancers · Yao Wang · 2022 · 64 citations · Cited by this paper
  29. A low-bias and sensitive small RNA library preparation method using randomized splint ligation · Sean Maguire · 2020 · 55 citations · Cited by this paper
  30. Transfer RNA-Derived Fragments, the Underappreciated Regulatory Small RNAs in Microbial Pathogenesis · Zhongyou Li · 2021 · 48 citations · Cited by this paper
  31. Interplay between bile acids, gut microbiota, and the tumor immune microenvironment: mechanistic insights and therapeutic strategies · Yan Tong · 2025 · 48 citations · Cited by this paper
  32. Serum hsa_tsr016141 as a Kind of tRNA-Derived Fragments Is a Novel Biomarker in Gastric Cancer · Xinliang Gu · 2021 · 40 citations · Cited by this paper
  33. Identifying Differentially Expressed tRNA-Derived Small Fragments as a Biomarker for the Progression and Metastasis of Colorectal Cancer · Hui Chen · 2022 · 40 citations · Cited by this paper
  34. Transfer RNA ‐derived fragment 5′ tRF‐Gly promotes the development of hepatocellular carcinoma by direct targeting of carcinoembryonic antigen‐related cell adhesion molecule 1 · Dekai Liu · 2022 · 28 citations · Cited by this paper
  35. The 3’tsRNAs are aminoacylated: Implications for their biogenesis · Ziwei Liu · 2021 · 27 citations · Cited by this paper
  36. Transfer RNA-derived fragment tRF-23-Q99P9P9NDD promotes progression of gastric cancer by targeting ACADSB · Yu Zhang · 2024 · 25 citations · Cited by this paper
  37. Pancreatic stellate cell‐derived exosomal tRF‐19‐PNR8YPJZ promotes proliferation and mobility of pancreatic cancer through AXIN2 · Wenpeng Cao · 2023 · 23 citations · Cited by this paper
  38. A tRF ‐5a fragment that regulates radiation resistance of colorectal cancer cells by targeting MKNK1 · Tianyi Huang · 2023 · 21 citations · Cited by this paper
  39. The Emerging Function and Promise of tRNA-Derived Small RNAs in Cancer · Na Yang · 2024 · 20 citations · Cited by this paper

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