Research map: Therapeutic potential of the Nrf2 activator omaveloxolone in spinocerebellar ataxia type 3 in cellular and Drosophila models

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  24. Proteolytic cleavage of polyglutamine-expanded ataxin-3 is critical for aggregation and sequestration of non-expanded ataxin-3 · Annette Haacke · 2006 · 125 citations · Cited by this paper
  25. p62 Plays a Protective Role in the Autophagic Degradation of Polyglutamine Protein Oligomers in Polyglutamine Disease Model Flies · Yuji Saitoh · 2014 · 63 citations · Cited by this paper
  26. Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway · Yu‐Ling Wu · 2017 · 54 citations · Cited by this paper
  27. Nuclear Aggregation of Polyglutamine-expanded Ataxin-3 · Péter Breuer · 2010 · 36 citations · Cited by this paper
  28. Autophagy in Spinocerebellar Ataxia Type 3: From Pathogenesis to Therapeutics · Rodrigo Paulino · 2023 · 31 citations · Cited by this paper
  29. p62/Sequestosome 1 Regulates Aggresome Formation of Pathogenic Ataxin-3 with Expanded Polyglutamine · Liang Zhou · 2014 · 29 citations · Cited by this paper
  30. Mitochondrial Dysfunction in Spinocerebellar Ataxia Type 3 Is Linked to VDAC1 Deubiquitination · Tina Harmuth · 2022 · 29 citations · Cited by this paper
  31. Treatment with Caffeic Acid and Resveratrol Alleviates Oxidative Stress Induced Neurotoxicity in Cell and Drosophila Models of Spinocerebellar Ataxia Type3 · Yu‐Ling Wu · 2017 · 24 citations · Cited by this paper
  32. Heterogeneous nonataxic phenotypes of spinocerebellar ataxia in a Taiwanese population · Szu‐Ju Chen · 2019 · 19 citations · Cited by this paper
  33. In Vitro Efficacy and Molecular Mechanism of Curcumin Analog in Pathological Regulation of Spinocerebellar Ataxia Type 3 · Yu‐Ling Wu · 2022 · 17 citations · Cited by this paper
  34. Autophagy Function and Benefits of Autophagy Induction in Models of Spinocerebellar Ataxia Type 3 · Maxinne Watchon · 2023 · 17 citations · Cited by this paper
  35. The Role of NRF2 in Trinucleotide Repeat Expansion Disorders · Kuo‐Hsuan Chang · 2024 · 11 citations · Cited by this paper
  36. Erinacine A-Enriched Hericium erinaceus Mycelium Ethanol Extract Lessens Cellular Damage in Cell and Drosophila Models of Spinocerebellar Ataxia Type 3 by Improvement of Nrf2 Activation · Yu‐Ling Wu · 2024 · 11 citations · Cited by this paper

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