Research map: Genetic and epigenetic alterations in human gametes following cryopreservation: human evidence and insights from mammalian animal models

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  1. Mature oocyte cryopreservation: a guideline · 2012 · 927 citations · Cited by this paper
  2. Pressure-activated disassembly of cryoprotectant supramolecules in isochoric freezing · 2026 · Related
  3. Highly efficient vitrification for cryopreservation of human oocytes and embryos: The Cryotop method · Masashige Kuwayama · 2006 · 862 citations · Cited by this paper
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  5. Role of sperm chromatin abnormalities and DNA damage in male infertility · Ashok Kumar Agarwal · 2003 · 858 citations · Cited by this paper
  6. Differential expression patterns of selective energy metabolism associated genes in fresh and freeze-thawed bubaline spermatozoa at uniform durations of in vitro capacitation · 2026 · Related
  7. Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans · Shiny Titus · 2013 · 525 citations · Cited by this paper
  8. The interconnection of cryobiology and tissue engineering · 2026 · Related
  9. Cryopreservation: An Overview of Principles and Cell-Specific Considerations · David M. Whaley · 2021 · 409 citations · Cited by this paper
  10. Feeds supplemented with L-carnitine and varying oil sources improve the Rhamdia quelen thawed sperm redox balance and sperm movement · 2026 · Related
  11. The role of heat shock proteins in reproduction · Andreas Neuer · 2000 · 299 citations · Cited by this paper
  12. Protective effects of seminal exosomes on cryopreserved sperm via inhibiting oxidative damage · 2026 · Related
  13. Sperm DNA fragmentation testing: Summary evidence and clinical practice recommendations · Sandro Cassiano Esteves · 2020 · 276 citations · Cited by this paper
  14. Cryopreservation of spermatogonia from Yesso scallop, Mizuhopecten yessoensis · 2026 · Related
  15. Mitochondrial Dysfunction and Oxidative Stress Caused by Cryopreservation in Reproductive Cells · Roberto Gualtieri · 2021 · 257 citations · Cited by this paper
  16. Cryoprotective effects of mangiferin-loaded chitosan nanoparticles on buffalo sperm: Antioxidant, apoptotic, and motility insights · 2026 · Related
  17. Meiotic spindle assembly and chromosome segregation in oocytes · Isma Bennabi · 2016 · 237 citations · Cited by this paper
  18. Study on a novel vacuum sublimation-rehydration thawing method for large yellow croaker (Larimichthys crocea) and effect of sublimation time on thawing performance · 2026 · Related
  19. A confocal microscopy analysis of the spindle and chromosome configurations of human oocytes cryopreserved at the germinal vesicle and metaphase II stage · Irene Boiso · 2002 · 219 citations · Cited by this paper
  20. Hemoglobin-based high-throughput assessment of lyoprotectant efficacy · 2026 · Related
  21. DNA integrity and motility of human spermatozoa after standard slow freezing versus cryoprotectant-free vitrification · Evgenia Isachenko · 2004 · 215 citations · Cited by this paper
  22. Oxidative Stress and Male Infertility: The Protective Role of Antioxidants · Aris Kaltsas · 2023 · 189 citations · Cited by this paper
  23. Sperm-derived histones contribute to zygotic chromatin in humans · Godfried W. van der Heijden · 2008 · 183 citations · Cited by this paper
  24. A Decade of Exploring the Mammalian Sperm Epigenome: Paternal Epigenetic and Transgenerational Inheritance · Alexandre Champroux · 2018 · 183 citations · Cited by this paper
  25. Effect of cryopreservation on sperm parameters, lipid peroxidation and antioxidant enzymes activity in fowl semen · Agnieszka Partyka · 2012 · 170 citations · Cited by this paper
  26. Impact of Cryopreservation on Spermatozoa Freeze-Thawed Traits and Relevance OMICS to Assess Sperm Cryo-Tolerance in Farm Animals · Ibrar Muhammad Khan · 2021 · 157 citations · Cited by this paper
  27. Small RNAs in spermatogenesis · Ram Prakash Yadav · 2013 · 154 citations · Cited by this paper
  28. Proteomic characteristics of human sperm cryopreservation · Shangqian Wang · 2013 · 148 citations · Cited by this paper
  29. Gene expression profiling of human oocytes following in vivo or in vitro maturation · Gayle M Jones · 2008 · 147 citations · Cited by this paper
  30. Chromosome and spindle configurations of human oocytes matured in vitro after cryopreservation at the germinal vesicle stage · Sung-Eun Park · 1997 · 142 citations · Cited by this paper
  31. Identification of protein changes in human spermatozoa throughout the cryopreservation process · O. A. Bogle · 2016 · 140 citations · Cited by this paper
  32. Sperm global DNA methylation level: association with semen parameters and genome integrity · Debbie Montjean · 2015 · 139 citations · Cited by this paper
  33. Live birth rate after female fertility preservation for cancer or haematopoietic stem cell transplantation: a systematic review and meta-analysis of the three main techniques; embryo, oocyte and ovarian tissue cryopreservation · Éloïse Fraison · 2022 · 126 citations · Cited by this paper
  34. Sperm Cryopreservation Today: Approaches, Efficiency, and Pitfalls · Sanja Ozimic · 2023 · 123 citations · Cited by this paper
  35. All you need to know about sperm RNAs · Joana Santiago · 2021 · 113 citations · Cited by this paper
  36. Genetic factors as potential molecular markers of human oocyte and embryo quality · Qing Sang · 2021 · 112 citations · Cited by this paper
  37. Effects of cryopreservation on the epigenetic profile of cells · Atasi Chatterjee · 2016 · 106 citations · Cited by this paper
  38. The impact of mitochondrial impairments on sperm function and male fertility: a systematic review · Minoo Vahedi Raad · 2024 · 104 citations · Cited by this paper
  39. The Art of Packaging the Sperm Genome: Molecular and Structural Basis of the Histone-To-Protamine Exchange · Lindsay Moritz · 2022 · 95 citations · Cited by this paper

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