Research map: Curcumin protects SH-SY5Y cells against glutamate-induced excitotoxicity by maintaining genomic integrity and antioxidant balance

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  1. Antioxidant and radical scavenging properties of curcumin · Tuba Parlak Ak · 2008 · 1943 citations · Cited by this paper
  2. Regulatory toxicity and safety profiling of N-acetyl-L-tryptophan with special emphasis on genotoxicity and male reproductive toxicity via intramuscular route of administration · 2026 · Related
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  5. Nitric Oxide Scavenging by Curcuminoids · Sreejayan · 1997 · 1138 citations · Cited by this paper
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  7. Curcumin, a Novel p300/CREB-binding Protein-specific Inhibitor of Acetyltransferase, Represses the Acetylation of Histone/Nonhistone Proteins and Histone Acetyltransferase-dependent Chromatin Transcription · Karanam Balasubramanyam · 2004 · 832 citations · Cited by this paper
  8. Comparative studies on the effect of busulfan in different drug carriers on the gonadal functions of male Wistar rats · 2026 · Related
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  11. Ischemia-Triggered Glutamate Excitotoxicity From the Perspective of Glial Cells · Denisa Belov Kirdajova · 2020 · 441 citations · Cited by this paper
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  13. Antioxidant Potential of Curcumin—A Meta-Analysis of Randomized Clinical Trials · Karolina Jakubczyk · 2020 · 357 citations · Cited by this paper
  14. Salicylic acid attenuates paclitaxel-induced toxicity by modulating interleukin expression: an in vivo study · 2026 · Related
  15. Going the Extra (Synaptic) Mile: Excitotoxicity as the Road Toward Neurodegenerative Diseases · Adam Armada‐Moreira · 2020 · 325 citations · Cited by this paper
  16. Integrated network toxicology, machine learning, and bioinformatics analysis reveals sodium dehydroacetate-induced coagulation dysfunction in colorectal cancer · 2026 · Related
  17. Asiatic acid, a pentacyclic triterpene in Centella asiatica, attenuates glutamate-induced cognitive deficits in mice and apoptosis in SH-SY5Y cells · Min-fang Xu · 2012 · 158 citations · Cited by this paper
  18. Synthesis and multidimensional investigation of a tetra-substituted imidazole derivative: Spectroscopy, DFT/NLO properties, toxicity analysis, molecular docking, and dynamics simulation · 2026 · Related
  19. Curcumin protects DNA damage in a chronically arsenic-exposed population of West Bengal · Jaydip Biswas · 2010 · 132 citations · Cited by this paper
  20. Propolis ameliorates thioacetamide induced hepatic fibrosis in rats: an in vivo and in silico approach · 2026 · Related
  21. Curcumin as a potential protective compound against cardiac diseases · Shuai Jiang · 2017 · 132 citations · Cited by this paper
  22. Neuroprotective Effects of Curcumin in Neurodegenerative Diseases · Giuseppe Genchi · 2024 · 111 citations · Cited by this paper
  23. Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage · Zhongwei Sun · 2010 · 107 citations · Cited by this paper
  24. Effect of Curcumin Against Oxidation of Biomolecules by Hydroxyl Radicals · Sai Krishna Borra · 2014 · 73 citations · Cited by this paper
  25. The initiator of neuroexcitotoxicity and ferroptosis in ischemic stroke: Glutamate accumulation · Genhao Fan · 2023 · 72 citations · Cited by this paper
  26. Neuroprotective effects of Scrophularia buergeriana extract against glutamate-induced toxicity in SH-SY5Y cells · Hae‐Young Lee · 2019 · 50 citations · Cited by this paper
  27. Deferoxamine and Curcumin Loaded Nanocarriers Protect Against Rotenone-Induced Neurotoxicity · Leah Mursaleen · 2019 · 46 citations · Cited by this paper
  28. Advances of curcumin in nervous system diseases: the effect of regulating oxidative stress and clinical studies · Yuxun Wei · 2024 · 38 citations · Cited by this paper
  29. Neuroprotective Effects of Neuropeptide Y on Human Neuroblastoma SH-SY5Y Cells in Glutamate Excitotoxicity and ER Stress Conditions · Viswanthram Palanivel · 2022 · 32 citations · Cited by this paper
  30. Assessment of the ameliorative effect of curcumin on pendimethalin-induced genetic and biochemical toxicity · Ali Acar · 2022 · 30 citations · Cited by this paper
  31. Neuroprotective Potential of Curcumin in Neurodegenerative Diseases: Clinical Insights Into Cellular and Molecular Signaling Pathways · Md. Rezaul Islam · 2025 · 25 citations · Cited by this paper
  32. Dissociations of free radicals to generate protons, electrophiles or nucleophiles: role in DNA strand breaks · John C. Walton · 2021 · 13 citations · Cited by this paper
  33. The protective effect of Moringa oleifera plant extract against glutamate-induced DNA damage and reduced cell viability in a primary retinal ganglion cell line · Musarat Amina · 2021 · 11 citations · Cited by this paper
  34. Oxidative genomic or genotoxic stress in neurodegeneration: Mechanisms and therapeutic avenues · Taslim Uddin · 2025 · 10 citations · Cited by this paper
  35. Curcumin/cyclodextrin polymer inclusion complex attenuates ethanol‐induced liver injury by inhibition of DNA damage in mice · Jianping Chen · 2023 · 9 citations · Cited by this paper
  36. Curcumin Improves Hippocampal Cell Bioenergetics, Redox and Inflammatory Markers, and Synaptic Proteins, Regulating Mitochondrial Calcium Homeostasis · Claudia Jara · 2025 · 9 citations · Cited by this paper
  37. Impact of free curcumin and curcumin nanocapsules on viability and oxidative status of neural cell lines · Bianca Fagan Bissacotti · 2021 · 8 citations · Cited by this paper
  38. Common Mitochondrial Targets of Curcumin and Cinnamic Acid, the Membrane-Active Natural Phenolic Compounds · Татьяна Александровна Федотчева · 2024 · 6 citations · Cited by this paper
  39. Protective effect of Apelin-13 on D-glutamic acid-induced excitotoxicity in SH-SY5Y cell line: An in-vitro study · Kadriye Yağmur Oruç · 2024 · 4 citations · Cited by this paper

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