Research map: ITPKB suppresses ER calcium release to promote CXCL9 expression and enhance immunotherapy sensitivity in triple-negative breast cancer

Back to the article

Papers in this map

  1. AutoDock Vina 1.2.0: New Docking Methods, Expanded Force Field, and Python Bindings · Jérôme Eberhardt · 2021 · 7483 citations · Cited by this paper
  2. Tailored HER2 ECD mRNA-LNP vaccines boost CD8+ T cell-mediated antitumor immunity for HER2-positive tumor suppression · 2026 · Related
  3. CB-Dock2: improved protein–ligand blind docking by integrating cavity detection, docking and homologous template fitting · Yang Liu · 2022 · 2075 citations · Cited by this paper
  4. Resistance to CAR-based cell therapy: Mechanisms and overcoming strategies · 2026 · Related
  5. PrankWeb: a web server for ligand binding site prediction and visualization · Lukáš Jendele · 2019 · 536 citations · Cited by this paper
  6. Low dose radiation induces new protein synthesis that promotes cancer radiotherapy resistance · 2026 · Related
  7. A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast · Bhupinder Pal · 2021 · 526 citations · Cited by this paper
  8. Long-term outcomes and exploratory analysis from a randomized phase 3 trial of radiation dose escalation in definitive chemoradiotherapy for locally advanced esophageal squamous cell carcinoma · 2026 · Related
  9. Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia · Alvin Wei Tian Ng · 2017 · 389 citations · Cited by this paper
  10. ZBED6-Driven Nucleotide Metabolic Reprogramming Improves Sensitivity to anti-PD1 Therapy in NK/T Cell Lymphoma · 2026 · Related
  11. Advances in immunotherapy for triple-negative breast cancer · Yang Liu · 2023 · 337 citations · Cited by this paper
  12. PRKCA and ABCB1 dual-enriched exosomes are key drivers of drug resistance in chronic myeloid leukemia · 2026 · Related
  13. Cytokines in cancer · Courtney T.S. Kureshi · 2024 · 213 citations · Cited by this paper
  14. Mechanistic analysis on epigenetic programming of tumor drug resistance · 2026 · Related
  15. CXCL9: evidence and contradictions for its role in tumor progression · Qiang Ding · 2016 · 178 citations · Cited by this paper
  16. NHE6-driven endosome-autophagy axis confers proteasome inhibitor resistance in multiple myeloma · 2026 · Related
  17. The Transcriptional Coactivator CREB-binding Protein Cooperates with STAT1 and NF-κB for Synergistic Transcriptional Activation of the CXC Ligand 9/Monokine Induced by Interferon-γ Gene · Miki Hiroi · 2002 · 107 citations · Cited by this paper
  18. Progress toward personalized management of stage II/III triple negative breast cancer · 2025 · Related
  19. The role of tumor microenvironment and immune cell crosstalk in triple-negative breast cancer (TNBC): Emerging therapeutic opportunities · Hussein Sabit · 2025 · 87 citations · Cited by this paper
  20. Gramine suppresses triple-negative breast cancer by inducing ferroptosis via CUL3-mediated ubiquitination of MTDH · 2026 · Related
  21. Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation · Andrew T. Miller · 2007 · 78 citations · Cited by this paper
  22. Epigenetic modulations in triple-negative breast cancer: Therapeutic implications for tumor microenvironment · Linlin Zhou · 2024 · 78 citations · Cited by this paper
  23. ATP-induced Ca2+-signalling mechanisms in the regulation of mesenchymal stem cell migration · Lin‐Hua Jiang · 2017 · 70 citations · Cited by this paper
  24. Reliable measurement of free Ca2+ concentrations in the ER lumen using Mag-Fluo-4 · Ana M. Rossi · 2020 · 66 citations · Cited by this paper
  25. Suppression of ITPKB degradation by Trim25 confers TMZ resistance in glioblastoma through ROS homeostasis · Yuanliang Yan · 2024 · 63 citations · Cited by this paper
  26. Application of biomimetic nanovaccines in cancer immunotherapy: A useful strategy to help combat immunotherapy resistance · Zhijie Xu · 2024 · 63 citations · Cited by this paper
  27. Drug resistance in breast cancer: Mechanisms and strategies for management · Guoyu Wu · 2025 · 61 citations · Cited by this paper
  28. Calcineurin in development and disease · Lei Chen · 2021 · 56 citations · Cited by this paper
  29. The Multifaceted Roles of CXCL9 Within the Tumor Microenvironment · Shiyong Neo · 2020 · 52 citations · Cited by this paper
  30. ROS-regulated phosphorylation of ITPKB by CAMK2G drives cisplatin resistance in ovarian cancer · Jie Li · 2022 · 43 citations · Cited by this paper
  31. Cancer Immunotherapy Based on the Bidirectional Reprogramming of the Tumor Microenvironment by a “Brakes Off/ Step on the Accelerator” Core‐Shell Manganese Phosphate/siPD‐L1 Modulator · Fei Xia · 2025 · 42 citations · Cited by this paper
  32. Discovery of Novel Apigenin–Piperazine Hybrids as Potent and Selective Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors for the Treatment of Cancer · Huan Long · 2021 · 40 citations · Cited by this paper
  33. Zinc-copper bimetallic nanoplatforms trigger photothermal-amplified cuproptosis and cGAS-STING activation for enhancing triple-negative breast cancer immunotherapy · Bangyi Zhou · 2025 · 40 citations · Cited by this paper
  34. Inositol-triphosphate 3-kinase B confers cisplatin resistance by regulating NOX4-dependent redox balance · Chaoyun Pan · 2019 · 38 citations · Cited by this paper
  35. Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1 · Dandan Lin · 2022 · 32 citations · Cited by this paper
  36. Requirement of Two NFATc4 Transactivation Domains for CBP Potentiation · Teddy Tat Chi Yang · 2001 · 29 citations · Cited by this paper
  37. Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca 2+ mobilization and the inflammatory activity of dendritic cells · Laura Marongiu · 2021 · 28 citations · Cited by this paper
  38. Inositol 1,4,5-trisphosphate 3-kinase B (Itpkb) controls survival, proliferation and cytokine production in mouse peripheral T cells · Valérie Pouillon · 2012 · 24 citations · Cited by this paper
  39. New therapeutic targets in immune disorders: ItpkB, Orai1 and UNC93B · Yina H. Huang · 2008 · 24 citations · Cited by this paper

Source: OpenAlex (CC0)