Research map: Bispecific Antibodies for Acute Myeloid Leukemia: From Bone Marrow Immune Niche to Clinical Translation

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  1. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell · Dominique A. Bonnet · 1997 · 7038 citations · Cited by this paper
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  17. Maintenance of the Hematopoietic Stem Cell Pool by CXCL12-CXCR4 Chemokine Signaling in Bone Marrow Stromal Cell Niches · Tatsuki Sugiyama · 2006 · 2424 citations · Cited by this paper
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  19. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study · Sylvie Castaigné · 2012 · 1018 citations · Cited by this paper
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  22. Monoclonal Antibodies in Cancer Therapy · David J. Zahavi · 2020 · 844 citations · Cited by this paper
  23. The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells · Craig T. Jordan · 2000 · 826 citations · Cited by this paper
  24. Cellular Niches Controlling B Lymphocyte Behavior within Bone Marrow during Development · Koji Tokoyoda · 2004 · 795 citations · Cited by this paper
  25. Acute leukemia incidence and patient survival among children and adults in the United States, 2001-2007 · Graça M. Dores · 2011 · 643 citations · Cited by this paper
  26. Myeloproliferative Neoplasia Remodels the Endosteal Bone Marrow Niche into a Self-Reinforcing Leukemic Niche · Koen Schepers · 2013 · 616 citations · Cited by this paper
  27. Efficacy, Safety, and Biomarkers of Response to Azacitidine and Nivolumab in Relapsed/Refractory Acute Myeloid Leukemia: A Nonrandomized, Open-Label, Phase II Study · Naval Guastad Daver · 2018 · 579 citations · Cited by this paper
  28. TIM-3 Is a Promising Target to Selectively Kill Acute Myeloid Leukemia Stem Cells · Yoshikane Kikushige · 2010 · 489 citations · Cited by this paper
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  30. Identification of Therapeutic Targets for Quiescent, Chemotherapy-Resistant Human Leukemia Stem Cells · Yoriko Saito · 2010 · 465 citations · Cited by this paper
  31. Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion · Bijender Kumar · 2017 · 457 citations · Cited by this paper
  32. The novel AML stem cell–associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells · Anna van Rhenen · 2007 · 442 citations · Cited by this paper
  33. Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia · David S. Ritchie · 2013 · 440 citations · Cited by this paper
  34. Tagraxofusp in Blastic Plasmacytoid Dendritic-Cell Neoplasm · Naveen Pemmaraju · 2019 · 437 citations · Cited by this paper
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  36. CD96 is a leukemic stem cell-specific marker in human acute myeloid leukemia · Naoki Hosen · 2007 · 380 citations · Cited by this paper
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  38. Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody · Torsten Dreier · 2002 · 359 citations · Cited by this paper
  39. Phase I Trial of Autologous CAR T Cells Targeting NKG2D Ligands in Patients with AML/MDS and Multiple Myeloma · Susanne H.C. Baumeister · 2018 · 333 citations · Cited by this paper

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