Research map: The Dual Role of Cell Death in Skeletal Muscle Homeostasis and Disease: Mechanisms and Therapeutic Targeting

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  1. The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3 · Hui Song · 2016 · 453 citations · Cited by this paper
  2. TRPV4-associated proinflammatory macrophage activation and cardiomyocyte ferroptosis-related injury in myocardial ischemia/reperfusion: involvement of USP47/Wnt/β-catenin signaling · Qiong Wang · 2026 · Cites this paper
  3. Characteristics Three waves of pyripyropene fungal alkaloids and synthetic derivatives targeting ACAT2 as insecticides, anti-atherosclerosis and anticancer agents. · 2026 · Related
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  5. Role of the cGAS-STING signaling pathway in diabetes mellitus and its complications: from mechanisms to therapeutics · Guangdong Qi · 2026 · Cites this paper
  6. Low-molecular-weight fucoidan inhibits HMGB1-induced thromboinflammation by modulating HMGB1-TLR4 axis · 2026 · Related
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  8. 5-Methoxyflavone Alleviates High-Fat Diet-induced Atherosclerosis in ApoE-/- Mice through Modulation of ACADM · Haoyang Zheng · 2026 · Cites this paper
  9. Poly(I:C) and QS-21 combination suppresses breast tumor growth and metastasis by repolarizing tumor associated macrophages to anti-tumor macrophages · 2026 · Related
  10. Mitochondrial dysfunction: roles in skeletal muscle atrophy · Xin Chen · 2023 · 313 citations · Cited by this paper
  11. Damage-associated molecular patterns in skeletal muscle: a double-edged sword − from sterile inflammation initiation to precision targeted therapeutic strategies · Zihui Gao · 2026 · Cites this paper
  12. Rebastinib inhibits cerebral cavernous malformation in a chronic mouse model · 2026 · Related
  13. Skeletal muscle mitochondrial remodeling in exercise and diseases · Zhenji Gan · 2018 · 292 citations · Cited by this paper
  14. RIPK3 Inhibition Mitigates Denervated Muscle Atrophy via NOX4‐Mediated Mitochondrial Restoration and Inflammation Suppression · 2026 · Related
  15. PANoptosis: A Unique Innate Immune Inflammatory Cell Death Modality · Pandian Nagakannan · 2022 · 281 citations · Cited by this paper
  16. PGC-1α mediates ER stress–driven apoptotic signaling during gemfibrozil treatment in glioblastoma · 2026 · Related
  17. Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7 · Wei A. He · 2014 · 251 citations · Cited by this paper
  18. CTSB-Associated Inflammation and Macrophage Interaction in Heart Failure Following Myocardial Infarction and Potential Therapeutic Implications of Quercetin · 2026 · Related
  19. Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy · Peiling Luan · 2021 · 208 citations · Cited by this paper
  20. S14G-humanin (HNG) ameliorates diabetic nephropathy tubular injury by inhibiting Z-DNA/ZBP1-mediated necroptosis · 2026 · Related
  21. Metastatic cancers promote cachexia through ZIP14 upregulation in skeletal muscle · Gang Wang · 2018 · 192 citations · Cited by this paper
  22. Induction and Propagation of Ferroptosis Evasion by FTH1P7 Drives Sorafenib Resistance in Hepatocellular Carcinoma · 2026 · Related
  23. Transferrin receptor 1 ablation in satellite cells impedes skeletal muscle regeneration through activation of ferroptosis · Hongrong Ding · 2021 · 186 citations · Cited by this paper
  24. Muscle degeneration in aging Drosophila flies: the role of mechanical stress · 2024 · Related
  25. Mitochondrial permeability transition pore-dependent necrosis · Dexter J. Robichaux · 2022 · 183 citations · Cited by this paper
  26. AMPK/SIRT1/PGC‐1α Signaling Pathway: Molecular Mechanisms and Targeted Strategies From Energy Homeostasis Regulation to Disease Therapy · Junyang Chen · 2025 · 171 citations · Cited by this paper
  27. Selective activation of PFKL suppresses the phagocytic oxidative burst · Neri Amara · 2021 · 163 citations · Cited by this paper
  28. Mechanical Stress‐induced DNA damage and rac‐p38MAPK Signal Pathways Mediate p53‐dependent Apoptosis in Vascular Smooth Muscle Cells · Manuel Mayr · 2002 · 157 citations · Cited by this paper
  29. FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging · Seung-Min Lee · 2020 · 145 citations · Cited by this paper
  30. The Role of Autophagy in Skeletal Muscle Diseases · Qianghua Xia · 2021 · 126 citations · Cited by this paper
  31. Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies · Kexin Wang · 2022 · 126 citations · Cited by this paper
  32. ACSL4 contributes to ferroptosis‐mediated rhabdomyolysis in exertional heat stroke · Sixiao He · 2022 · 119 citations · Cited by this paper
  33. Ferroptosis in a sarcopenia model of senescence accelerated mouse prone 8 (SAMP8) · Yan Huang · 2020 · 118 citations · Cited by this paper
  34. Exercise-mediated reinnervation of skeletal muscle in elderly people: An update · Claudia Coletti · 2022 · 114 citations · Cited by this paper
  35. TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis · Jingying Wu · 2023 · 113 citations · Cited by this paper
  36. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration · Shenao Zhou · 2020 · 107 citations · Cited by this paper
  37. Amelioration of diabetes‐induced inflammation mediated pyroptosis, sarcopenia, and adverse muscle remodelling by bone morphogenetic protein‐7 · Chandrakala Aluganti Narasimhulu · 2021 · 107 citations · Cited by this paper
  38. Trimetazidine attenuates dexamethasone-induced muscle atrophy via inhibiting NLRP3/GSDMD pathway-mediated pyroptosis · Lı Wang · 2021 · 106 citations · Cited by this paper
  39. Biogenesis and function of extracellular vesicles in pathophysiological processes of skeletal muscle atrophy · Wei Wang · 2022 · 104 citations · Cited by this paper

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