Research map: Bone organoids and mitochondrial reprogramming

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Papers in this map

  1. Mitochondrial transfer between cells can rescue aerobic respiration · Jeffrey L. Spees · 2006 · 1157 citations · Cited by this paper
  2. From niche to organoid: Engineering bone tissues through microenvironmental insights · 2025 · Related
  3. The assembly, regulation and function of the mitochondrial respiratory chain · Irene Vercellino · 2021 · 993 citations · Cited by this paper
  4. Signal-driven interplay between lipid peroxidation and ferroptosis orchestrates osteoarthritis degeneration · 2026 · Related
  5. Angiocrine functions of organ-specific endothelial cells · Shahin Rafii · 2016 · 976 citations · Cited by this paper
  6. Dermal fibroblasts attenuate osteoarthritis by restoring synovial fibroblast homeostasis · 2026 · Related
  7. Mitochondria in oxidative stress, inflammation and aging: from mechanisms to therapeutic advances · Xiaojun Xu · 2025 · 765 citations · Cited by this paper
  8. Author's reply to the Letters regarding ‘Selecting between UKA and HTO in the grey zone’ · 2026 · Related
  9. The bone remodelling cycle · J E Kenkre · 2018 · 699 citations · Cited by this paper
  10. Unraveling stress fractures: from cellular and molecular mechanisms to therapeutic approaches · 2026 · Related
  11. Mesenchymal stem cells: Cell therapy and regeneration potential · Christina Brown · 2019 · 638 citations · Cited by this paper
  12. Therapeutic effect of mitochondrial transfer on bone tissue diseases: treatment strategy of mitochondrial transplantation and delivery technology · 2026 · Related
  13. Vascularized and Complex Organ Buds from Diverse Tissues via Mesenchymal Cell-Driven Condensation · Takanori Takebe · 2015 · 477 citations · Cited by this paper
  14. Dynamic collaboration between mitochondria and organelles: mechanisms, functions, and disease implications · 2026 · Related
  15. Molecular mechanisms of mitochondrial dynamics · Luis Carlos Tábara · 2024 · 407 citations · Cited by this paper
  16. Ganoderic acid A accelerates osteoporotic fracture healing by promoting osteogenic differentiation via estrogen receptor alpha binding · 2026 · Related
  17. Role of mitochondrial reactive oxygen species in homeostasis regulation · Baoyi Zhang · 2022 · 392 citations · Cited by this paper
  18. Ubiquitination in intervertebral disc degeneration: from mechanisms to potential therapeutic strategies · 2026 · Related
  19. Recent Advances in 3D Printing of Smart Scaffolds for Bone Tissue Engineering and Regeneration · Xun Yuan · 2024 · 335 citations · Cited by this paper
  20. Emerging roles of the metabolite succinate in bone-related diseases · 2025 · Related
  21. Human disease models in drug development · Anna Löwa · 2023 · 322 citations · Cited by this paper
  22. FoxO-Mediated Defense against Oxidative Stress in Osteoblasts Is Indispensable for Skeletal Homeostasis in Mice · Elena Ambrogini · 2010 · 314 citations · Cited by this paper
  23. Sirt3-mediated mitophagy regulates AGEs-induced BMSCs senescence and senile osteoporosis · Yuanyuan Guo · 2021 · 311 citations · Cited by this paper
  24. The role of osteoblasts in energy homeostasis · Naomi Dirckx · 2019 · 298 citations · Cited by this paper
  25. Mitochondrial Management of Reactive Oxygen Species · Gaetana Napolitano · 2021 · 285 citations · Cited by this paper
  26. Analytic Models of Oxygen and Nutrient Diffusion, Metabolism Dynamics, and Architecture Optimization in Three-Dimensional Tissue Constructs with Applications and Insights in Cerebral Organoids · Richard J. McMurtrey · 2015 · 255 citations · Cited by this paper
  27. The physiological metabolite α-ketoglutarate ameliorates osteoarthritis by regulating mitophagy and oxidative stress · Liang Liu · 2023 · 252 citations · Cited by this paper
  28. Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review · Jana Riegger · 2023 · 238 citations · Cited by this paper
  29. Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies · Abdullah Obaid Khan · 2022 · 214 citations · Cited by this paper
  30. Oxidative stress: A common pathological state in a high-risk population for osteoporosis · Chi Zhang · 2023 · 203 citations · Cited by this paper
  31. High-efficient engineering of osteo-callus organoids for rapid bone regeneration within one month · Chang Xie · 2022 · 188 citations · Cited by this paper
  32. Mutations in SEC24D, Encoding a Component of the COPII Machinery, Cause a Syndromic Form of Osteogenesis Imperfecta · Lutz Garbes · 2015 · 181 citations · Cited by this paper
  33. Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts · Kai Chen · 2020 · 170 citations · Cited by this paper
  34. Balancing ER-Mitochondrial Ca2+ Fluxes in Health and Disease · Jens Loncke · 2021 · 170 citations · Cited by this paper
  35. Glucose metabolism in bone · Courtney M. Karner · 2017 · 168 citations · Cited by this paper
  36. LRRc17 controls BMSC senescence via mitophagy and inhibits the therapeutic effect of BMSCs on ovariectomy-induced bone loss · Fei Liu · 2021 · 159 citations · Cited by this paper
  37. Trabecular bone organoid model for studying the regulation of localized bone remodeling · Yongkuk Park · 2021 · 153 citations · Cited by this paper
  38. Harnessing 4D Printing Bioscaffolds for Advanced Orthopedics · Xi Chen · 2022 · 151 citations · Cited by this paper
  39. Generation of complex bone marrow organoids from human induced pluripotent stem cells · Stephanie Frenz-Wiessner · 2024 · 144 citations · Cited by this paper

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