Research map: Yiqi Huoxue Jiedu formula protects against sepsis-associated lung injury by modulating macrophage mitophagy and mtDNA-STING signaling

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  1. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) · Mervyn Singer · 2016 · 29041 citations · Cited by this paper
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  17. XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury · Zheng Liu · 2022 · 369 citations · Cited by this paper
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  20. Wubi Shanyao Pills ameliorate glucocorticoid-induced osteoporosis by regulating bone marrow T cell homing as an immune intermediate to restore bone metabolism · 2026 · Related
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  23. Mitochondrial dysfunction in sepsis: mechanisms and therapeutic perspectives · Dongxue Hu · 2024 · 184 citations · Cited by this paper
  24. Biomarkers of inflammation and the etiology of sepsis · Inge Grondman · 2020 · 170 citations · Cited by this paper
  25. Panax Notoginseng Saponins: A Review of Its Mechanisms of Antidepressant or Anxiolytic Effects and Network Analysis on Phytochemistry and Pharmacology · Weijie Xie · 2018 · 156 citations · Cited by this paper
  26. Circulating mitochondrial DNA-triggered autophagy dysfunction via STING underlies sepsis-related acute lung injury · Qinjie Liu · 2021 · 141 citations · Cited by this paper
  27. The cGAS-STING pathway-dependent sensing of mitochondrial DNA mediates ocular surface inflammation · Weijie Ouyang · 2023 · 126 citations · Cited by this paper
  28. Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients · Hilary E. Faust · 2019 · 118 citations · Cited by this paper
  29. Inhibition of DRP1-dependent mitochondrial fission by Mdivi-1 alleviates atherosclerosis through the modulation of M1 polarization · Zedazhong Su · 2023 · 115 citations · Cited by this paper
  30. SESN2 protects against doxorubicin-induced cardiomyopathy via rescuing mitophagy and improving mitochondrial function · Panxia Wang · 2019 · 101 citations · Cited by this paper
  31. cGAS–STING, an important signaling pathway in diseases and their therapy · Qijie Li · 2024 · 74 citations · Cited by this paper
  32. Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis · Gan Wang · 2023 · 47 citations · Cited by this paper
  33. Mitochondrial Regulation of Macrophage Response Against Pathogens · Subhadip Choudhuri · 2021 · 46 citations · Cited by this paper
  34. RUNX1 promotes mitophagy and alleviates pulmonary inflammation during acute lung injury · Tang Xiao-ju · 2023 · 41 citations · Cited by this paper
  35. Clinical practice guideline on traditional Chinese medicine therapy alone or combined with antibiotics for sepsis · Guozhen Zhao · 2019 · 36 citations · Cited by this paper
  36. Pathogenesis and treatment strategies of sepsis-induced myocardial injury: modern and traditional medical perspectives · Wenwen Yang · 2025 · 33 citations · Cited by this paper
  37. Mitophagy-promoting miR-138-5p promoter demethylation inhibits pyroptosis in sepsis-associated acute lung injury · Fen Liu · 2022 · 30 citations · Cited by this paper
  38. Roles of ginsenosides in sepsis · Tao Yu · 2022 · 29 citations · Cited by this paper
  39. Clemastine mitigates sepsis-induced acute kidney injury in rats; the role of α-Klotho/TLR-4/MYD-88/NF-κB/ Caspase-3/ p-P38 MAPK signaling pathways · Mahmoud Abdelnaser · 2024 · 27 citations · Cited by this paper

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