Research map: Conditional Estimations for Seamless Phase II / III Clinical Trials Involving Multi‐Stage Early Stopping

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  1. A Multiple Testing Procedure for Clinical Trials · Peter C. O’Brien · 1979 · 3371 citations · Cited by this paper
  2. Choosing Covariate Balancing Methods for Causal Inference: Practical Insights From a Simulation Study · 2026 · Related
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  17. A group‐sequential design for clinical trials with treatment selection · Nigel Stallard · 2008 · 115 citations · Cited by this paper
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  19. P values for tests using a repeated significance test design · Kenneth B. Fairbanks · 1982 · 93 citations · Cited by this paper
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  21. Point estimates and confidence regions for sequential trials involving selection · Nigel Stallard · 2004 · 62 citations · Cited by this paper
  22. Shrinkage estimation in two‐stage adaptive designs with midtrial treatment selection · Máximo Carreras · 2012 · 60 citations · Cited by this paper
  23. Point estimation for adaptive trial designs I: A methodological review · David S. Robertson · 2022 · 57 citations · Cited by this paper
  24. Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility · Peter Kimani · 2013 · 40 citations · Cited by this paper
  25. The bias of the sample proportion following a group sequential phase II clinical trial · Myron N. Chang · 1989 · 36 citations · Cited by this paper
  26. Point estimation for adaptive trial designs II : Practical considerations and guidance · David S. Robertson · 2023 · 29 citations · Cited by this paper
  27. Uniformly minimum variance conditionally unbiased estimation in multi-arm multi-stage clinical trials · Nigel Stallard · 2018 · 25 citations · Cited by this paper
  28. Unbiased estimation in seamless phase II/III trials with unequal treatment effect variances and hypothesis‐driven selection rules · David S. Robertson · 2016 · 20 citations · Cited by this paper
  29. A comparison of methods for constructing confidence intervals after phase II/III clinical trials · Peter Kimani · 2013 · 15 citations · Cited by this paper
  30. Comparison of conditional bias-adjusted estimators for interim analysis in clinical trials with survival data · Masashi Shimura · 2017 · 13 citations · Cited by this paper
  31. Estimation of treatment effects following a sequential trial of multiple treatments · John Whitehead · 2020 · 11 citations · Cited by this paper
  32. Adjusting for treatment selection in phase II/III clinical trials with time to event data · Josephine N. Khan · 2022 · 6 citations · Cited by this paper
  33. Estimation of treatment effect in 2‐in‐1 adaptive design and some of its extensions · Wen Li · 2021 · 5 citations · Cited by this paper
  34. Adaptive two-stage seamless sequential design for clinical trials · Ping Gao · 2024 · 3 citations · Cited by this paper
  35. Confidence Intervals for Adaptive Trial Designs I: A Methodological Review · David S. Robertson · 2025 · 3 citations · Cited by this paper
  36. Seamless phase 2/3 oncology trial design with flexible sample size determination · Zhaoyang Teng · 2020 · 2 citations · Cited by this paper
  37. Confidence Intervals for Adaptive Trial Designs II : Case Study and Practical Guidance · David S. Robertson · 2025 · 2 citations · Cited by this paper
  38. Untitled · Cited by this paper

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