Research map: Functional Parameters of Hybridoma Cells: Methods of Evaluation and Biotechnological Relevance

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  1. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays · Tim R. Mosmann · 1983 · 56229 citations · Cited by this paper
  2. Autoantibodies as Precision Tools in Connective Tissue Diseases: From Epiphenomenon to Endophenotype · 2026 · Related
  3. Continuous cultures of fused cells secreting antibody of predefined specificity · Georges Köhler · 1975 · 17298 citations · Cited by this paper
  4. Microsecond Dynamics of Fc–CD16a Recognition: Impact of Mutations, Core Fucosylation, and Fc Asymmetry · 2026 · Related
  5. Apoptosis: A Review of Programmed Cell Death · Susan A. Elmore · 2007 · 13926 citations · Cited by this paper
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  7. Filamentous Fusion Phage: Novel Expression Vectors That Display Cloned Antigens on the Virion Surface · George P. Smith · 1985 · 4173 citations · Cited by this paper
  8. Development of Bispecific Antibody Targeting Human IL-17A and IL-6 · 2026 · Related
  9. The large-scale organization of metabolic networks · H. Jeong · 2000 · 4063 citations · Cited by this paper
  10. pIgR Stem Zone-Targeted Nanobodies as Apical-to-Basolateral Carriers for Inhaled Biologic Delivery Across Mucosal Barriers · 2026 · Related
  11. Phage antibodies: filamentous phage displaying antibody variable domains · John McCafferty · 1990 · 2429 citations · Cited by this paper
  12. The Shifting Paradigm of Monoclonal Antibodies in COVID-19 Management: From Early Triumphs to Viral Resistance and Future Perspectives · 2026 · Related
  13. Tetrazolium dyes as tools in cell biology: New insights into their cellular reduction · Michael V. Berridge · 2005 · 2224 citations · Cited by this paper
  14. Antibodies as Tools for Characterization, Isolation and Production Enhancement of Anti-Cancer Drugs and Steroidal Hormones from Ginsenoside and Solasodine Glycoside: A Review · 2026 · Related
  15. A better cell line for making hybridomas secreting specific antibodies · Marc J. Shulman · 1978 · 1618 citations · Cited by this paper
  16. Hybridoma technology: is it still useful? · 2021 · Related
  17. Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning · Thomas Tiller · 2007 · 1191 citations · Cited by this paper
  18. Monoclonal Antibodies in Pregnancy of Patients with Systemic Lupus Erythematosus: Friend or Foe? A Case Report of a Patient with Multiple Pregnancies · 2026 · Related
  19. Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains. · Sherie Leaver Morrison · 1984 · 1035 citations · Cited by this paper
  20. Biopsy-Confirmed Acute Interstitial Nephritis in Patients Treated with Immune Checkpoint Inhibitors: A Single-Center Retrospective Case Series · 2026 · Related
  21. Reproducibility crisis: Blame it on the antibodies · Monya Baker · 2015 · 867 citations · Cited by this paper
  22. Improving the efficacy of antibody-based cancer therapies · Paul M. Carter · 2001 · 829 citations · Cited by this paper
  23. Guidelines for cell viability assays · Senem Kamiloğlu · 2020 · 770 citations · Cited by this paper
  24. Cell culture processes for monoclonal antibody production · Feng Li · 2010 · 747 citations · Cited by this paper
  25. Reproducibility: Standardize antibodies used in research · Andrew M. Bradbury · 2015 · 668 citations · Cited by this paper
  26. Immunogenicity of engineered antibodies · William Ying Khee Hwang · 2005 · 634 citations · Cited by this paper
  27. Cell Proliferation and Cytotoxicity Assays · Aysun Adan · 2016 · 592 citations · Cited by this paper
  28. Electric field-induced cell-to-cell fusion · Ulrich S Zimmermann · 1982 · 578 citations · Cited by this paper
  29. Differences in promiscuity for antibody–FcRn interactions across species: implications for therapeutic antibodies · Raimund J. Ober · 2001 · 499 citations · Cited by this paper
  30. Anti‐mitotic activity of colchicine and the structural basis for its interaction with tubulin · Bhabatarak Bhattacharyya · 2007 · 499 citations · Cited by this paper
  31. Comparison of Trypan Blue Dye Exclusion and Fluorometric Assays for Mammalian Cell Viability Determinations · Steven A. Altman · 1993 · 401 citations · Cited by this paper
  32. Antigen-specific identification and cloning of hybridomas with a fluorescence-activated cell sorter. · David R. Parks · 1979 · 385 citations · Cited by this paper
  33. Optimization of therapeutic antibodies by predicting antigen specificity from antibody sequence via deep learning · Derek M. Mason · 2021 · 339 citations · Cited by this paper
  34. Assaying Cell Cycle Status Using Flow Cytometry · Kang Ho Kim · 2015 · 319 citations · Cited by this paper
  35. Human PCNA Structure, Function and Interactions · Amaia Gonzalez Magaña · 2020 · 295 citations · Cited by this paper
  36. Post-translational modifications of protein biopharmaceuticals · Gary Walsh · 2010 · 270 citations · Cited by this paper
  37. Do TUNEL and Other Apoptosis Assays Detect Cell Death in Preclinical Studies? · Razmik Mirzayans · 2020 · 234 citations · Cited by this paper
  38. Hybridoma technology a versatile method for isolation of monoclonal antibodies, its applicability across species, limitations, advancement and future perspectives · Hilal Ahmed Parray · 2020 · 227 citations · Cited by this paper
  39. Enzyme-Linked Immunosorbent Assay: Types and Applications · Hovhannes Hayrapetyan · 2023 · 202 citations · Cited by this paper

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