Research map: Luteolin as a urease inhibitor: A novel therapeutic strategy against Helicobacter pylori

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  1. Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report · Peter Malfertheiner · 2016 · 2970 citations · Cited by this paper
  2. Unveiling Mucorales infections: A cutting-edge longitudinal imaging approach for real-time infection and host-response monitoring in Galleria mellonella and mouse models · 2026 · Related
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  5. Helicobacter pylori: gastric cancer and beyond · D. Brent Polk · 2010 · 1167 citations · Cited by this paper
  6. Dissecting the essential role of luxS -relevant small RNAs in biofilm formation of Streptococcus mutans · 2026 · Related
  7. Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies · Nur Aziz · 2018 · 645 citations · Cited by this paper
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  10. Pathogenicity and virulence of Candida auris · 2026 · Related
  11. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mouse stomach · Masataka Tsuda · 1994 · 300 citations · Cited by this paper
  12. Herpesviruses and autophagy: An intracellular conflict · 2026 · Related
  13. Eradication therapy for peptic ulcer disease in Helicobacter pylori -positive people · Alexander Charles Ford · 2016 · 288 citations · Cited by this paper
  14. A porcine model of chronic hepatitis E virus (HEV) infection identifies male reproductive glands as sites of viral persistence · 2026 · Related
  15. Isolation of Luteolin and Luteolin-7- O -glucoside from Dendranthema morifolium Ramat Tzvel and Their Pharmacokinetics in Rats · Lie-Chwen Lin · 2015 · 260 citations · Cited by this paper
  16. Galleria mellonella proteomic response to infection with Streptococcus pyogenes · 2026 · Related
  17. Urease inhibitors as potential drugs for gastric and urinary tract infections: a patent review · Paulina Kosikowska · 2011 · 200 citations · Cited by this paper
  18. Bridging environmental pollution and immune dysregulation: How microplastics disrupt gut homeostasis to promote allergic diseases · 2026 · Related
  19. Helicobacter pylori urease for diagnosis of Helicobacter pylori infection: A mini review · David Yates Graham · 2018 · 189 citations · Cited by this paper
  20. The CCR2 inflammatory pathway is a target for improving severe disease and pulmonary inflammation in experimental COVID-19 · 2026 · Related
  21. Suppression of Helicobacter pylori-induced gastritis by green tea extract in Mongolian gerbils · Satoshi Matsubara · 2003 · 162 citations · Cited by this paper
  22. Randomized, Double-Blind Trial of Lithostat™ (Acetohydroxamic Acid) in the Palliative Treatment of Infection-Induced Urinary Calculi · Donald P. Griffith · 1991 · 156 citations · Cited by this paper
  23. Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis · Tzu‐Chan Hong · 2023 · 156 citations · Cited by this paper
  24. A Case Series of a Luteolin Formulation (Neuroprotek®) in Children with Autism Spectrum Disorders · Theoharis Constantin Theoharides · 2012 · 122 citations · Cited by this paper
  25. Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori · David Strugatsky · 2012 · 113 citations · Cited by this paper
  26. Primary Antibiotic Resistance of Helicobacter pylori in China · Yi Hu · 2017 · 112 citations · Cited by this paper
  27. Helicobacter pyloriutilises urea for amino acid synthesis · Craig L. Williams · 1996 · 94 citations · Cited by this paper
  28. Shigella flexneri: an emerging pathogen · Iqbal Nisa · 2020 · 85 citations · Cited by this paper
  29. A new coumarin compound DCH combats methicillin-resistant Staphylococcus aureus biofilm by targeting arginine repressor · Di Qu · 2020 · 83 citations · Cited by this paper
  30. Coptisine-induced inhibition ofHelicobacter pylori: elucidation of specific mechanisms by probing urease active site and its maturation process · Cailan Li · 2018 · 76 citations · Cited by this paper
  31. In VitroandIn VivoAntibacterial Activities of Patchouli Alcohol, a Naturally Occurring Tricyclic Sesquiterpene, against Helicobacter pylori Infection · Yifei Xu · 2017 · 67 citations · Cited by this paper
  32. Helicobacter pylori promotes hepatic fibrosis in the animal model · Moon-Jung Goo · 2009 · 66 citations · Cited by this paper
  33. Global prevalence of Helicobacter pylori antibiotic resistance among children in the world health organization regions between 2000 and 2023: a systematic review and meta-analysis · Aryan Salahi‐Niri · 2024 · 65 citations · Cited by this paper
  34. N-monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation · Weiyi Li · 2019 · 57 citations · Cited by this paper
  35. Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment · Bing-Jie Han · 2018 · 55 citations · Cited by this paper
  36. The Exposure of Luteolin Is Much Lower than That of Apigenin in Oral Administration of Flos Chrysanthemi Extract to Rats · Zhongjian Chen · 2011 · 52 citations · Cited by this paper
  37. Improving Oral Bioavailability of Luteolin Nanocrystals by Surface Modification of Sodium Dodecyl Sulfate · Jiali Liu · 2021 · 48 citations · Cited by this paper
  38. Relative Contribution of Small and Large Intestine to Deglycosylation and Absorption of Flavonoids fromChrysanthemun morifoliumExtract · Xin-Yan Lu · 2010 · 43 citations · Cited by this paper
  39. Genetic diversity and virulence characteristics of Helicobacter pylori isolates in different human ethnic groups · Alfizah Hanafiah · 2019 · 42 citations · Cited by this paper

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