Research map: Integrative Bioinformatics and Docking-Based In Silico Toxicity Assessment of Plastic Additives: Insights into Neurotoxic, Reproductive, and Carcinogenic Risks and Associated Molecular Pathways

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An overview of chemical additives present in plastics: Migration, release, fate and environmental impact during their use, disposal and recycling · John N. Hahladakis · 2017 · 3878 citations · Cited by this paper
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PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease · Hui‐Zhi Long · 2021 · 516 citations · Cited by this paper
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GSK-3 as potential target for therapeutic intervention in cancer · James Andrew McCubrey · 2014 · 515 citations · Cited by this paper
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Environmental Chemical Contaminants in Food: Review of a Global Problem · Lesa A. Thompson · 2019 · 380 citations · Cited by this paper
The hazardous threat of Bisphenol A: Toxicity, detection and remediation · Ayon Kumar Tarafdar · 2021 · 364 citations · Cited by this paper
ESR1 mutations in breast cancer · Derek Dustin · 2019 · 320 citations · Cited by this paper
Plastic Products Leach Chemicals That Induce In Vitro Toxicity under Realistic Use Conditions · Lisa Zimmermann · 2021 · 275 citations · Cited by this paper
Efficient analysis of toxicity and mechanisms of environmental pollutants with network toxicology and molecular docking strategy: Acetyl tributyl citrate as an example · Shujun Huang · 2023 · 249 citations · Cited by this paper
Plastic additives and microplastics as emerging contaminants: Mechanisms and analytical assessment · João Pinto da Costa · 2022 · 247 citations · Cited by this paper
Additives of plastics: Entry into the environment and potential risks to human and ecological health · Naga Raju Maddela · 2023 · 244 citations · Cited by this paper
GSK‐3 in Neurodegenerative Diseases · Peng Lei · 2011 · 183 citations · Cited by this paper
A review of estrogen receptor α gene (ESR1) polymorphisms, mood, and cognition · Erin E. Sundermann · 2010 · 159 citations · Cited by this paper
How will additives shape the future of plastics? · Rudolf Pfaendner · 2006 · 154 citations · Cited by this paper
Akt: a key transducer in cancer · Pei‐Jane Tsai · 2022 · 126 citations · Cited by this paper
Exploring the mechanism of PPCPs on human metabolic diseases based on network toxicology and molecular docking · Menghang Cheng · 2025 · 121 citations · Cited by this paper
Association of GSK3B With Alzheimer Disease and Frontotemporal Dementia · Barbara Schaffer · 2008 · 100 citations · Cited by this paper
Understanding the leaching of plastic additives and subsequent risks to ecosystems · Asmara Iftikhar · 2024 · 80 citations · Cited by this paper
A systematic comparison of the developmental vascular toxicity of bisphenol A and its alternatives in vivo and in vitro · Guixiang Ji · 2021 · 79 citations · Cited by this paper
Derivatives of Plastics as Potential Carcinogenic Factors: The Current State of Knowledge · Jacek Baj · 2022 · 78 citations · Cited by this paper
Environmental triggers and future risk of developing autoimmune diseases: Molecular mechanism and network toxicology analysis of bisphenol A · Yanggang Hong · 2024 · 75 citations · Cited by this paper
The Known and Unknown: Investigating the Carcinogenic Potential of Plastic Additives · Sophia Vincoff · 2024 · 73 citations · Cited by this paper
An integrated assessment of ecological and human health risks of per- and polyfluoroalkyl substances through toxicity prediction approaches · Naima Hamid · 2023 · 67 citations · Cited by this paper

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