Research map: Identification of TNFRSF12A as a key regulator of stemness and immunosuppression in a novel glioma subtype via multi-omics analysis and experimental validation

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  1. The adaptive transition of glioblastoma stem cells and its implications on treatments · Zeyu Wang · 2021 · 161 citations · Cited by this paper
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  17. Glioma Stem Cells: Novel Data Obtained by Single-Cell Sequencing · Alisa M. Gisina · 2022 · 60 citations · Cited by this paper
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  20. Single-Cell RNA-Sequencing Shift in the Interaction Pattern Between Glioma Stem Cells and Immune Cells During Tumorigenesis · You Zhai · 2020 · 44 citations · Cited by this paper
  21. Interaction of tumor-associated microglia/macrophages and cancer stem cells in glioma · Xiangling Zhu · 2023 · 37 citations · Cited by this paper
  22. Hypoxia-induced TREM1 promotes mesenchymal-like states of glioma stem cells via alternatively activating tumor-associated macrophages · Minhai Dong · 2024 · 31 citations · Cited by this paper
  23. TWEAK/Fn14 signalling driven super-enhancer reprogramming promotes pro-metastatic metabolic rewiring in triple-negative breast cancer · Nicholas Sim · 2024 · 31 citations · Cited by this paper
  24. ThPOK transcriptionally inactivates TNFRSF12A to increase the proliferation of T cells with the involvement of the NF-kB pathway · Lingli Xia · 2021 · 30 citations · Cited by this paper
  25. Glioblastoma microenvironment: The stromal interactions · Ramazan Uyar · 2022 · 30 citations · Cited by this paper
  26. Reactivating PTEN to impair glioma stem cells by inhibiting cytosolic iron-sulfur assembly · Jianxing Yin · 2024 · 30 citations · Cited by this paper
  27. Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomics · Meysam Motevasseli · 2024 · 28 citations · Cited by this paper
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  30. CREB5 promotes the proliferation and self-renewal ability of glioma stem cells · Hyun‐Jin Kim · 2024 · 25 citations · Cited by this paper
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  32. Glioblastoma stem cell metabolism and immunity · Joseph Hawly · 2024 · 23 citations · Cited by this paper
  33. Gene regulatory network topology governs resistance and treatment escape in glioma stem-like cells · James Hugh Park · 2024 · 21 citations · Cited by this paper
  34. A low level of tumor necrosis factor α in tumor microenvironment maintains the self-renewal of glioma stem cells by Vasorin-mediated glycolysis · Yang Zhang · 2024 · 15 citations · Cited by this paper
  35. Stress-induced pro-inflammatory glioblastoma stem cells secrete TNFAIP6 to enhance tumor growth and induce suppressive macrophages · Danling Gu · 2025 · 15 citations · Cited by this paper
  36. Machine learning unveils immune-related signature in multicenter glioma studies · Sha Yang · 2024 · 10 citations · Cited by this paper
  37. The Oncogenic Role of TNFRSF12A in Colorectal Cancer and Pan-Cancer Bioinformatics Analysis · Chuyue Wang · 2024 · 10 citations · Cited by this paper
  38. Role of TNFRSF12A in cell proliferation, apoptosis, and proinflammatory cytokine expression by regulating the MAPK and NF-κB pathways in thyroid cancer cells · Qiu Xu · 2024 · 8 citations · Cited by this paper
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