Research map: Bacteriophage therapy in the era of antimicrobial resistance: clinical evidence, translational challenges, and emerging regulatory frameworks (2020–2026)

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Papers in this map

  1. Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050 · Mohsen Naghavi · 2024 · 3685 citations · Cited by this paper
  2. Antibiotic Resistance and the Return to a Pre-Antibiotic Era: A Critical Narrative Review of a Global Catastrophe · Shaurya Prakash · 2026 · Cites this paper
  3. Spheroid versus monolayer culture: proteomic insights into divergent pathways in myxofibrosarcoma · 2026 · Related
  4. Phage therapy: From biological mechanisms to future directions · Steffanie Ann Strathdee · 2023 · 830 citations · Cited by this paper
  5. Comparative analysis of transformer architectures for brain tumor classification · 2025 · Related
  6. The interplay between diet and the gut microbiome: implications for health and disease · Fiona C. Ross · 2024 · 614 citations · Cited by this paper
  7. Unusual dual metastasis of hepatocellular carcinoma to the orbit and oral cavity: a case report and literature review · 2026 · Related
  8. Safety of bacteriophage therapy in severe Staphylococcus aureus infection · Aleksandra Petrović Fabijan · 2020 · 478 citations · Cited by this paper
  9. A deep learning framework for classifying autism spectrum disorder from children’s facial images using a multi-scale ViT architecture and edge computing · 2025 · Related
  10. Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study · Jean‐Paul Pirnay · 2024 · 452 citations · Cited by this paper
  11. Associations between self-reported adherence to antihypertensive medications and potential mechanisms of behavior change in a general outpatient sample · 2026 · Related
  12. Bacteriophage Therapy: Clinical Trials and Regulatory Hurdles · Lucy L. Furfaro · 2018 · 370 citations · Cited by this paper
  13. Phagetherapy updates: New frontiers against antibiotic resistance · 2025 · Related
  14. Current challenges and future opportunities of phage therapy · Diana Priscila Pires · 2020 · 353 citations · Cited by this paper
  15. Bacterial resistance to phage therapy: Mechanisms and strategies to overcome it · 2025 · Related
  16. The Magistral Phage · Jean‐Paul Pirnay · 2018 · 349 citations · Cited by this paper
  17. Harnessing ‘phage training’ to bolster the therapeutic potential of bacteriophages · 2025 · Related
  18. An Overview of the Recent Advances in Antimicrobial Resistance · Manuela Thaís dos Santos Oliveira · 2024 · 284 citations · Cited by this paper
  19. Engineered phage with antibacterial CRISPR–Cas selectively reduce E. coli burden in mice · Yilmaz Emre Gençay · 2023 · 274 citations · Cited by this paper
  20. Positive and negative aspects of bacteriophages and their immense role in the food chain · Soniya Ashok Ranveer · 2024 · 221 citations · Cited by this paper
  21. Current Clinical Landscape and Global Potential of Bacteriophage Therapy · Nicole Hitchcock · 2023 · 187 citations · Cited by this paper
  22. Regulations of phage therapy across the world · Qimao Yang · 2023 · 176 citations · Cited by this paper
  23. Phage Therapy—Challenges, Opportunities and Future Prospects · Beata Zalewska-Pia̧tek · 2023 · 171 citations · Cited by this paper
  24. Pharmacokinetics/pharmacodynamics of phage therapy: a major hurdle to clinical translation · Sue C. Nang · 2023 · 160 citations · Cited by this paper
  25. Developing Phage Therapy That Overcomes the Evolution of Bacterial Resistance · Agnès Oromí-Bosch · 2023 · 153 citations · Cited by this paper
  26. A Comprehensive Review on Phage Therapy and Phage-Based Drug Development · Longzhu Cui · 2024 · 133 citations · Cited by this paper
  27. Clinical Experience of Personalized Phage Therapy Against Carbapenem-Resistant Acinetobacter baumannii Lung Infection in a Patient With Chronic Obstructive Pulmonary Disease · Xin Tan · 2021 · 122 citations · Cited by this paper
  28. Personalized inhaled bacteriophage therapy for treatment of multidrug-resistant Pseudomonas aeruginosa in cystic fibrosis · Benjamin K. Chan · 2025 · 112 citations · Cited by this paper
  29. Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial · Paul J. Kim · 2024 · 110 citations · Cited by this paper
  30. Advancing Phage Therapy: A Comprehensive Review of the Safety, Efficacy, and Future Prospects for the Targeted Treatment of Bacterial Infections · Marco Palma · 2024 · 103 citations · Cited by this paper
  31. Phage Therapy in Poland – a Centennial Journey to the First Ethically Approved Treatment Facility in Europe · Maciej Żaczek · 2020 · 101 citations · Cited by this paper
  32. European regulatory aspects of phage therapy: magistral phage preparations · Gilbert Verbeken · 2021 · 99 citations · Cited by this paper
  33. Bacteriophage Rescue Therapy of a Vancomycin-Resistant Enterococcus faecium Infection in a One-Year-Old Child following a Third Liver Transplantation · Kevin Paul · 2021 · 75 citations · Cited by this paper
  34. Taking Bacteriophage Therapy Seriously: A Moral Argument · Gilbert Verbeken · 2014 · 55 citations · Cited by this paper
  35. Bacteriophage Therapy: Discovery, Development, and FDA Approval Pathways · Sarfaraz K. Niazi · 2025 · 53 citations · Cited by this paper
  36. The Current Landscape of Phage–Antibiotic Synergistic (PAS) Interactions · Brittany S. I. Supina · 2025 · 47 citations · Cited by this paper
  37. Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance · Kyung Duk Moon · 2025 · 43 citations · Cited by this paper
  38. Pharmacokinetics and pharmacodynamics of bacteriophage therapy: a review with a focus on multidrug-resistant Gram-negative bacterial infections · Maria Siopi · 2024 · 42 citations · Cited by this paper
  39. Bacteriophages for the Targeted Control of Foodborne Pathogens · Emmanuel W. Bumunang · 2023 · 40 citations · Cited by this paper

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