Research map: Intestinal epithelial SETD2 maintains gut microbial homeostasis to attenuate colitis

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Papers in this map

  1. Intestinal epithelial cells: regulators of barrier function and immune homeostasis · Lance W. Peterson · 2014 · 3262 citations · Cited by this paper
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  9. Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation · John W. Edmunds · 2007 · 551 citations · Cited by this paper
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  15. Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis · Jiawei Wu · 2020 · 406 citations · Cited by this paper
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  17. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation · Lirui Wang · 2016 · 400 citations · Cited by this paper
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  19. Epigenetic regulation by gut microbiota · Vivienne Woo · 2022 · 327 citations · Cited by this paper
  20. Ubc9‐mediated SUMOylation of Ninj1 alleviates inflammatory responses in hepatic ischaemia/reperfusion injury · 2026 · Related
  21. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications · Joachim Mankertz · 2007 · 309 citations · Cited by this paper
  22. Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis · Theresa Alenghat · 2013 · 254 citations · Cited by this paper
  23. A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice · Tyson R. Chiaro · 2017 · 237 citations · Cited by this paper
  24. Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease–Associated Colorectal Cancer · Kristiina Rajamäki · 2021 · 232 citations · Cited by this paper
  25. SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways · Huairui Yuan · 2020 · 216 citations · Cited by this paper
  26. Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice · Holger Sann · 2013 · 212 citations · Cited by this paper
  27. Extraintestinal manifestations in inflammatory bowel disease – epidemiology, genetics, and pathogenesis · Thomas Greuter · 2019 · 212 citations · Cited by this paper
  28. Crosstalk between the microbiome and epigenome: messages from bugs · Yufeng Qin · 2017 · 202 citations · Cited by this paper
  29. Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota · Alicia S. Wellman · 2017 · 192 citations · Cited by this paper
  30. KDM5B regulates embryonic stem cell self‐renewal and represses cryptic intragenic transcription · Liangqi Xie · 2011 · 184 citations · Cited by this paper
  31. Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis · Marion Darnaud · 2017 · 155 citations · Cited by this paper
  32. Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes · Tiffany D. Schaible · 2011 · 150 citations · Cited by this paper
  33. Unraveling host regulation of gut microbiota through the epigenome–microbiome axis · Michael Le Pepke · 2024 · 111 citations · Cited by this paper
  34. DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis · Ronald Alan Harris · 2014 · 77 citations · Cited by this paper
  35. Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome · Luis Carlos Veloza · 2022 · 77 citations · Cited by this paper
  36. The gut peptide Reg3g links the small intestine microbiome to the regulation of energy balance, glucose levels, and gut function · Jae Hoon Shin · 2022 · 75 citations · Cited by this paper
  37. Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization · Kyung Ku Jang · 2023 · 67 citations · Cited by this paper
  38. Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by Regulating the “Host–Microbe” Interaction · Jing Shao · 2021 · 64 citations · Cited by this paper
  39. Loss of Sirt1 Function Improves Intestinal Anti-Bacterial Defense and Protects from Colitis-Induced Colorectal Cancer · Giuseppe Lo Sasso · 2014 · 58 citations · Cited by this paper

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