Research map: Central nervous system concentrations of nano- and microplastics and risk of amyotrophic lateral sclerosis

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Papers in this map

  1. Are We Speaking the Same Language? Recommendations for a Definition and Categorization Framework for Plastic Debris · Nanna B. Hartmann · 2019 · 2888 citations · Cited by this paper
  2. Intracellular fluid accumulation underlies brain volume increases in early Alzheimer’s disease · 2026 · Related
  3. Current opinion: What is a nanoplastic? · Julien Gigault · 2018 · 1990 citations · Cited by this paper
  4. Incomplete T cell tolerance and epitope-specific responses to the NR1 subunit in NMDA receptor antibody-associated encephalitis · 2026 · Related
  5. Bioaccumulation of microplastics in decedent human brains · Alexander J. Nihart · 2025 · 855 citations · Cited by this paper
  6. Brain-injury and Alzheimer’s disease biomarkers are elevated in patients with suspected infection and physiological derangement: importance for context-specific interpretation of Alzheimer’s biomarkers · 2026 · Related
  7. The plastic brain: neurotoxicity of micro- and nanoplastics · Minne Prüst · 2020 · 806 citations · Cited by this paper
  8. Individualized phenotyping of functional amyotrophic lateral sclerosis pathology in sensorimotor cortex · 2026 · Related
  9. Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology · Claire Bridel · 2019 · 785 citations · Cited by this paper
  10. Soluble high-molecular-weight amyloid-β species derived from amyloid-β-laden brains induce cerebral β-amyloidosis · 2026 · Related
  11. A Review of Human Exposure to Microplastics and Insights Into Microplastics as Obesogens · Kurunthachalam Kannan · 2021 · 617 citations · Cited by this paper
  12. Survival motor neuron protein-independent amelioration of spinal muscular atrophy by pharmacological inhibition of c-Jun-NH2 terminal kinase · 2026 · Related
  13. Exposure to microplastics (<10 μm) associated to plastic bottles mineral water consumption: The first quantitative study · Pietro Zuccarello · 2019 · 427 citations · Cited by this paper
  14. Classifying irritable bowel syndrome using spatio-temporal graph convolution networks on brain functional MRI data · 2026 · Related
  15. The landscape of micron-scale particles including microplastics in human enclosed body fluids · Quanquan Guan · 2022 · 143 citations · Cited by this paper
  16. Neurological manifestations and genotype–phenotype correlations in NDUFAF6 -associated mitochondrial disease · 2026 · Related
  17. Global Prevalence and Incidence of Amyotrophic Lateral Sclerosis · Christina M. Wolfson · 2023 · 140 citations · Cited by this paper
  18. Long-term effects of preterm birth on cortical folding trajectories in early childhood · 2026 · Related
  19. Neurotoxicities induced by micro/nanoplastics: A review focusing on the risks of neurological diseases · Shuang Liu · 2024 · 136 citations · Cited by this paper
  20. Dual mechanism of anti-seizure medications in controlling seizure activity · 2026 · Related
  21. First evidence of microplastics in human ovarian follicular fluid: An emerging threat to female fertility · Luigi Montano · 2025 · 130 citations · Cited by this paper
  22. Microplastic Human Dietary Uptake from 1990 to 2018 Grew across 109 Major Developing and Industrialized Countries but Can Be Halved by Plastic Debris Removal · Xiang Zhao · 2024 · 115 citations · Cited by this paper
  23. Blood-brain barrier damage accelerates the accumulation of micro- and nanoplastics in the human central nervous system · Jian Ming Xie · 2024 · 115 citations · Cited by this paper
  24. The amyotrophic lateral sclerosis exposome: recent advances and future directions · Stephen A. Goutman · 2023 · 98 citations · Cited by this paper
  25. Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms · Hang Sun · 2024 · 82 citations · Cited by this paper
  26. Lead, cadmium and mercury in cerebrospinal fluid and risk of amyotrophic lateral sclerosis: A case-control study · Marco Vinceti · 2017 · 73 citations · Cited by this paper
  27. The effects of micro- and nanoplastics on the central nervous system: A new threat to humanity? · Yanxu Zheng · 2024 · 70 citations · Cited by this paper
  28. Exploring toxicological pathways of microplastics and nanoplastics: Insights from animal and cellular models · Luna Bridgeman · 2025 · 67 citations · Cited by this paper
  29. Characterization of estrogenic and androgenic activity of phthalates by the XenoScreen YES/YAS in vitro assay · Radosław Czernych · 2017 · 65 citations · Cited by this paper
  30. Py–GC–MS analysis for microplastics: Unlocking matrix challenges and sample recovery when analyzing wastewater for polypropylene and polystyrene · Jeanette Lykkemark · 2024 · 61 citations · Cited by this paper
  31. Heterogeneity in ALSFRS-R decline and survival: a population-based study in Italy · ERRALS Group · 2015 · 57 citations · Cited by this paper
  32. Occurrence and distribution of micro(meso)plastic-sorbed heavy metals and metalloids in sediments, Gulf of Guinea coast (SE Atlantic) · Omowunmi H. Fred-Ahmadu · 2021 · 57 citations · Cited by this paper
  33. A review on micro- and nanoplastics in humans: Implication for their translocation of barriers and potential health effects · Cui-Lan Bai · 2024 · 55 citations · Cited by this paper
  34. Pesticides, polychlorinated biphenyls and polycyclic aromatic hydrocarbons in cerebrospinal fluid of amyotrophic lateral sclerosis patients: a case-control study · Marco Vinceti · 2017 · 49 citations · Cited by this paper
  35. Amyotrophic lateral sclerosis incidence following exposure to inorganic selenium in drinking water: A long-term follow-up · Marco Vinceti · 2019 · 47 citations · Cited by this paper
  36. The neurotoxic threat of micro- and nanoplastics: evidence from In Vitro and In Vivo models · Ana Margarida Araújo · 2025 · 45 citations · Cited by this paper
  37. Association of microplastics in human cerebrospinal fluid with Alzheimer’s disease-related changes · Ping He · 2025 · 44 citations · Cited by this paper
  38. A systematic review of the potential neurotoxicity of micro-and nanoplastics: the known and unknown · Kinga Vojnits · 2025 · 41 citations · Cited by this paper
  39. CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression · Qionghua Sun · 2020 · 39 citations · Cited by this paper

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