Research map: Pediatric ependymoma in the molecular era: real-world experience with diagnostic correlation and long-term clinical outcomes

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  1. DNA methylation-based classification of central nervous system tumours · David Capper · 2018 · 3229 citations · Cited by this paper
  2. Long-term outcomes and late effects of surgery and radiotherapy in adult intracranial ependymoma patients · 2026 · Related
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  4. Fractionated stereotactic radiotherapy (fSRT) for symptomatic WHO grade 1 cavernous sinus meningiomas: long-term local control, clinical response, and toxicity outcomes · 2026 · Related
  5. Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups · Kristian W. Pajtler · 2015 · 1264 citations · Cited by this paper
  6. Prognostic impact of concomitant leptomeningeal disease in breast cancer patients with brain metastases: a large single-center cohort study · 2026 · Related
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  9. New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs · Dominik Sturm · 2016 · 1027 citations · Cited by this paper
  10. Frameless stereotactic radiosurgery in the management of brain metastases: long-term oncologic and toxicity outcomes · 2026 · Related
  11. Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts · David W. Ellison · 2011 · 315 citations · Cited by this paper
  12. Intratumoral hemorrhage in patients with brain metastasis from systemic tumors: risk factors and prognostic assessment · 2026 · Related
  13. Primary postoperative chemotherapy without radiotherapy for intracranial ependymoma in children: the UKCCSG/SIOP prospective study · Richard Guy Grundy · 2007 · 264 citations · Cited by this paper
  14. Therapeutic hybrid intelligence with neural and knowledge-based expert reasoning for SRS (THINKERS): an AI model for meningioma · 2026 · Related
  15. Conformal Radiation Therapy for Pediatric Ependymoma, Chemotherapy for Incompletely Resected Ependymoma, and Observation for Completely Resected, Supratentorial Ependymoma · Thomas E. Merchant · 2019 · 238 citations · Cited by this paper
  16. Dual AI models for gamma knife radiosurgery in craniopharyngioma: prescription dose modeling and outcome risk prediction · 2026 · Related
  17. Molecular Staging of Intracranial Ependymoma in Children and Adults · Andrey Korshunov · 2010 · 232 citations · Cited by this paper
  18. Incidence and predictors of hemorrhage in pediatric low-grade glioma · 2026 · Related
  19. MYCN amplification drives an aggressive form of spinal ependymoma · David R. Ghasemi · 2019 · 188 citations · Cited by this paper
  20. Therapeutic Hybrid Intelligence with Neural and Knowledge-based Expert Reasoning for SRS (THINKERS): an AI model for GBM · 2026 · Related
  21. DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies · Ed C. Schwalbe · 2013 · 184 citations · Cited by this paper
  22. Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas · Tuyu Zheng · 2021 · 115 citations · Cited by this paper
  23. Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q · Lorena Viviana Baroni · 2021 · 89 citations · Cited by this paper
  24. Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors · Philipp Sievers · 2021 · 82 citations · Cited by this paper
  25. Advances in the classification of pediatric brain tumors through DNA methylation profiling: From research tool to frontline diagnostic · Rahul Kumar · 2018 · 74 citations · Cited by this paper
  26. Pediatric ependymoma: an overview of a complex disease · Stephanie Theresa Jünger · 2021 · 68 citations · Cited by this paper
  27. CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort · Stephanie Theresa Jünger · 2020 · 54 citations · Cited by this paper
  28. Toward Improved Diagnosis Accuracy and Treatment of Children, Adolescents, and Young Adults With Ependymoma: The International SIOP Ependymoma II Protocol · Pierre F. Leblond · 2022 · 40 citations · Cited by this paper
  29. Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas · Lara Pohl · 2024 · 31 citations · Cited by this paper
  30. The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication” · Arnault Tauziède‐Espariat · 2020 · 30 citations · Cited by this paper
  31. Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter study · Andrew M. Donson · 2023 · 26 citations · Cited by this paper
  32. Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification · Jack Goddard · 2023 · 24 citations · Cited by this paper
  33. CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas · Arnault Tauziède‐Espariat · 2024 · 15 citations · Cited by this paper
  34. cIMPACT ‐ NOW update 10: Recommendations for defining new types for central nervous system tumor classification · Cynthia E Hawkins · 2025 · 14 citations · Cited by this paper
  35. Phase 3 randomized trial of postirradiation chemotherapy in patients with newly diagnosed ependymoma: A report from the Children’s Oncology Group · Amy A Smith · 2025 · 14 citations · Cited by this paper
  36. PLAG1 fusions define a third subtype of CNS embryonal tumor with PLAG family gene alteration · Michaela‐Kristina Keck · 2025 · 9 citations · Cited by this paper
  37. A brief history of ependymoma · David R. Ghasemi · 2026 · 4 citations · Cited by this paper
  38. Developing an advanced risk stratification model for pediatric intracranial ependymoma based on the prospective trial E-HIT2000 and subsequent registries · Katja von Hoff · 2025 · 3 citations · Cited by this paper
  39. The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland · Stefan Rutkowski · 2026 · 1 citation · Cited by this paper

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