Research map: Durable platelet response and immature platelet indices following sequential efgartigimod and eltrombopag therapy in a patient with refractory ITP

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  1. American Society of Hematology 2019 guidelines for immune thrombocytopenia · Cindy E. Neunert · 2019 · 1410 citations · Cited by this paper
  2. The renin-angiotensin system in healthy human platelets: expressed but inactive · 2025 · Related
  3. Updated international consensus report on the investigation and management of primary immune thrombocytopenia · Drew Provan · 2019 · 1151 citations · Cited by this paper
  4. Cardiometabolic risk factor burden associates with an immature platelet profile · 2025 · Related
  5. Suppression of in vitro megakaryocyte production by antiplatelet autoantibodies from adult patients with chronic ITP · Robert B. McMillan · 2003 · 540 citations · Cited by this paper
  6. Pre-activated lyophilized platelets show non-inferior hemostatic effect compared with fresh platelets in rabbits with traumatic bleeding and shock · 2025 · Related
  7. Immune thrombocytopenic purpura (ITP) plasma and purified ITP monoclonal autoantibodies inhibit megakaryocytopoiesis in vitro · Mei Chang · 2003 · 394 citations · Cited by this paper
  8. Identification of UDP-Glucuronosyltransferase mRNA in human platelets: differential levels in smokers and non-smokers · 2025 · Related
  9. Pathogenesis of immune thrombocytopenia · Sylvain Audia · 2017 · 382 citations · Cited by this paper
  10. Platelet parameters for distinguishing between inherited macrothrombocytopenia and acquired thrombocytopenia: a retrospective case–control study · 2025 · Related
  11. Pathogenesis of chronic immune thrombocytopenia: increased platelet destruction and/or decreased platelet production · Diane Jean Nugent · 2009 · 273 citations · Cited by this paper
  12. Thiazole orange: a complement to established methods for diagnosing inherited dense granule defects · 2025 · Related
  13. Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia · Francesco F. Zaja · 2010 · 262 citations · Cited by this paper
  14. In vitro investigations of the clot formation and resolution properties of cryopreserved platelets · 2026 · Related
  15. Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia · Adrian C. Newland · 2019 · 184 citations · Cited by this paper
  16. Evaluation of platelet dense granules by transmission electron microscopy in healthy pediatric donors and pediatric patients with suspected platelet disorders · 2025 · Related
  17. Platelet production and platelet destruction: assessing mechanisms of treatment effect in immune thrombocytopenia · Sarah J. Barsam · 2011 · 159 citations · Cited by this paper
  18. The NLRP3 inflammasome in platelets – form, functions, and future of the complex · 2025 · Related
  19. Misdiagnosis of primary immune thrombocytopenia and frequency of bleeding: lessons from the McMaster ITP Registry · Donald M. Arnold · 2017 · 139 citations · Cited by this paper
  20. A case with a novel GATA1 variant mimicking immune thrombocytopenia attacks · 2025 · Related
  21. In vivo effects of eltrombopag on platelet function in immune thrombocytopenia: no evidence of platelet activation · Bethan Psaila · 2012 · 115 citations · Cited by this paper
  22. Efficacy and safety of the neonatal Fc receptor inhibitor efgartigimod in adults with primary immune thrombocytopenia (ADVANCE IV): a multicentre, randomised, placebo-controlled, phase 3 trial · Catherine M. Broome · 2023 · 103 citations · Cited by this paper
  23. Reference guide for management of adult immune thrombocytopenia in Japan: 2019 Revision · Hirokazu Kashiwagi · 2020 · 66 citations · Cited by this paper
  24. Novel therapeutics and future directions for refractory immune thrombocytopenia · Hanny T. Al-Samkari · 2023 · 33 citations · Cited by this paper
  25. Platelet autoantibodies in the bone marrow of patients with immune thrombocytopenia · Sabrina Shrestha · 2020 · 31 citations · Cited by this paper
  26. Safety profile of efgartigimod from global clinical trials across multiple immunoglobulin G-mediated autoimmune diseases · Kelly Graham Gwathmey · 2025 · 26 citations · Cited by this paper
  27. Management of immune thrombocytopenia in elderly patients · Elisa Lucchini · 2018 · 23 citations · Cited by this paper
  28. Comparison of treatments for persistent/chronic immune thrombocytopenia: a systematic review and network meta-analysis · Yasuyuki Arai · 2018 · 22 citations · Cited by this paper
  29. Antibody binding to megakaryocytes in vivo in patients with immune thrombocytopenia · Donald M. Arnold · 2015 · 20 citations · Cited by this paper
  30. Efgartigimod alfa for the treatment of primary immune thrombocytopenia · Catherine M. Broome · 2023 · 17 citations · Cited by this paper
  31. Treatment of Critical Bleeds in Patients With Immune Thrombocytopenia: A Systematic Review · Saifur Rahman Chowdhury · 2024 · 5 citations · Cited by this paper

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