Research map: Engineering Diffusion-Controlled Drug Delivery Systems to Achieve a Desired Drug Release Profile: Mathematical Modelling and Optimisation

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  1. Thermo- and pH-responsive polymers in drug delivery☆ · Dirk Schmaljohann · 2006 · 3025 citations · Cited by this paper
  2. From Crystal Structure to Dissolution Enhancement: Cocrystal Engineering of Resmetirom to Address Its Solubility Challenge · 2026 · Related
  3. Imperialist competitive algorithm: An algorithm for optimization inspired by imperialistic competition · Esmaeil Atashpaz-Gargari · 2007 · 2652 citations · Cited by this paper
  4. Lateral Transport in Anisotropic Membrane during Permeation Study in Diffusion Cell · 2026 · Related
  5. Modeling of diffusion controlled drug delivery · Juergen Siepmann · 2011 · 937 citations · Cited by this paper
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  7. Polymer-Based Hydrogels Applied in Drug Delivery: An Overview · Hoc Thang Nguyen · 2023 · 807 citations · Cited by this paper
  8. Rational Design, Optimization and Bioinformatic Analysis of Anti-PD-L1 Peptide Conjugated Mocetinostat Prodrug Nanoparticles for Predictive Cancer Chemoimmunotherapeutic Efficacy · 2026 · Related
  9. Mathematical models in drug delivery: How modeling has shaped the way we design new drug delivery systems · Nicholas A. Peppas · 2014 · 569 citations · Cited by this paper
  10. Design, Synthesis and Characterization of Anti-CTLA4 Peptide Conjugated Gemcitabine Prodrug Nanoparticles for Targeted Lung Cancer Chemoimmunotherapy · 2026 · Related
  11. Fundamentals and Applications of Controlled Release Drug Delivery · Juergen Siepmann · 2011 · 523 citations · Cited by this paper
  12. Dead-Space Microdomains as Explicit Barriers to Extracellular Drug Transport in Alzheimer’s Disease · 2026 · Related
  13. Zero-order drug delivery: State of the art and future prospects · Mei‐Li Laracuente · 2020 · 383 citations · Cited by this paper
  14. Meta-Analysis and Physiologically-Based Modeling of the Pharmacokinetics and Pharmacodynamics of Dexamethasone in Horses · 2026 · Related
  15. Mathematical Modelling and Controlled Drug Delivery: Matrix Systems · Mario Grassi · 2005 · 369 citations · Cited by this paper
  16. CFD Modeling of Airflow and Aerosol Transport in the Human Respiratory System: A Comprehensive Review · 2026 · Related
  17. Advancements and Challenges in Additively Manufactured Functionally Graded Materials: A Comprehensive Review · Suhas Alkunte · 2024 · 139 citations · Cited by this paper
  18. Impact of Febrile State on Vancomycin Clearance in Pediatric Patients: Insights From Population Pharmacokinetic Modeling · 2026 · Related
  19. Mass diffusion through two-layer porous media: an application to the drug-eluting stent · Giuseppe Pontrelli · 2007 · 127 citations · Cited by this paper
  20. Women in Pharmaceutical Sciences: Progress, Possibility, and Lasting Impact · 2026 · Related
  21. Zero-order release of micro- and macromolecules from polymeric devices: the role of the burst effect · Balaji Narasimhan · 1997 · 110 citations · Cited by this paper
  22. Bimodal drug release achieved with multi-layer matrix tablets: transport mechanisms and device design · Alexander Streubel · 2000 · 106 citations · Cited by this paper
  23. Functionally Graded Biomaterials for Use as Model Systems and Replacement Tissues · Jeremy M. Lowen · 2020 · 106 citations · Cited by this paper
  24. Additive Manufacturing Strategies for Personalized Drug Delivery Systems and Medical Devices: Fused Filament Fabrication and Semi Solid Extrusion · Giulia Auriemma · 2022 · 106 citations · Cited by this paper
  25. A general model of coupled drug release and tissue absorption for drug delivery devices · Sean McGinty · 2015 · 98 citations · Cited by this paper
  26. Initial concentration distribution as a mechanism for regulating drug release from diffusion controlled and surface erosion controlled matrix systems · Ping I. Lee · 1986 · 84 citations · Cited by this paper
  27. Artificial intelligence and machine learning guided optimization in drug delivery · Helena Ros · 2026 · 33 citations · Cited by this paper
  28. Functionally Graded Materials and Structures: Unified Approach by Optimal Design, Metal Additive Manufacturing, and Image-Based Characterization · Rui F. Silva · 2024 · 24 citations · Cited by this paper
  29. Hybridization of the imperialist competitive algorithm and local search with application to ship design optimization · Daniële Peri · 2019 · 16 citations · Cited by this paper
  30. Modelling functionalized drug release for a spherical capsule · Elliot Joseph Carr · 2024 · 12 citations · Cited by this paper
  31. Release mechanisms of PLGA-based drug delivery systems: A review · Juergen Siepmann · 2025 · 11 citations · Cited by this paper
  32. Characterization of the Shells in Layer-By-Layer Nanofunctionalized Particles: A Computational Study · Emilio Barchiesi · 2022 · 10 citations · Cited by this paper
  33. Functionally Graded Surfaces and Materials: From Fabrication to Biomedical Applications · Min Hao · 2026 · 10 citations · Cited by this paper
  34. Modelling smart drug release with functionally graded materials · Gabriella Bretti · 2023 · 9 citations · Cited by this paper
  35. Drug Delivery from Nanogel Formulations: Mathematical Modeling of Different Release Profiles and Conditions · Antonio D’Ambrosio · 2025 · 8 citations · Cited by this paper
  36. Investigation of a Drug Release Moving Boundary Problem in a Swelling Polymeric Device · Morteza Garshasbi · 2022 · 2 citations · Cited by this paper
  37. Optimization of Initial Drug Distribution in Spherical Capsules for Personalized Release · Ankur Jain · 2022 · 2 citations · Cited by this paper
  38. Functionally-graded drug delivery systems with binding reactions: Analytical and stochastic approaches for the fraction of drug released · Obi A. Carwood · 2026 · 1 citation · Cited by this paper

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