Research map: Efficacy and safety of add-on topiramate vs. metformin on cardiometabolic profile in patients of schizophrenia on atypical antipsychotics with metabolic syndrome: an active-controlled, rater-blinded, parallel-design randomized controlled trial

Back to the article

Papers in this map

  1. Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man · David Richard Matthews · 1985 · 31767 citations · Cited by this paper
  2. Associations between plasma BDNF, VEGF, and EGF and cognition in drug-naïve schizophrenia with and without sleep disturbances · 2026 · Related
  3. A Systematic Review of Mortality in Schizophrenia · Sukanta Saha · 2007 · 2092 citations · Cited by this paper
  4. Esketamine multi-omic biomarker evaluation in major depressive disorder (EMBER-MDD): concept, objectives and methodologies of a non-clinical investigator-initiated study · 2026 · Related
  5. The clinical global impressions scale: applying a research tool in clinical practice. · Joan Busner · 2007 · 1775 citations · Cited by this paper
  6. Distinct effects of current suicidal symptoms and lifetime suicide attempts on C-reactive protein levels and executive function in young people with major affective disorders · 2026 · Related
  7. Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study · Julia Hippisley‐Cox · 2017 · 1760 citations · Cited by this paper
  8. Stressful life events and lifestyle factors are associated with elevated peripheral TNF-α levels in adults with depression without physical diseases · 2026 · Related
  9. Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-analysis · Christine Rummel‐Kluge · 2010 · 684 citations · Cited by this paper
  10. Family structure, depressive symptoms, and childhood maltreatment in Chinese adolescents: a mediation analysis · 2026 · Related
  11. Total Cholesterol/HDL Cholesterol Ratio vs LDL Cholesterol/HDL Cholesterol Ratio as Indices of Ischemic Heart Disease Risk in Men · Isabelle Lemieux · 2001 · 491 citations · Cited by this paper
  12. Machine learning-based integration identifies a 10-gene predictive signature and its classification patterns in schizophrenia · 2026 · Related
  13. Metformin in 2019 · James Flory · 2019 · 481 citations · Cited by this paper
  14. Major depressive disorder-alcohol use disorder comorbidity: diagnosis, mechanisms and treatment · 2026 · Related
  15. The Montreal Cognitive Assessment (MoCA) · John M. Hobson · 2015 · 306 citations · Cited by this paper
  16. Efficacy and EEG-ECG mechanisms of taVNS combined with TEAS for negative symptoms of schizophrenia: a protocol for a 2 × 2 factorial randomized controlled trial · 2026 · Related
  17. A Study of Insulin Resistance by HOMA-IR and its Cut-off Value to Identify Metabolic Syndrome in Urban Indian Adolescents · Singh Yashpal · 2013 · 236 citations · Cited by this paper
  18. Differential burden of five major mental disorders in the United States across the COVID-19 pandemic · 2026 · Related
  19. Effectiveness of Medications Used to Attenuate Antipsychotic-Related Weight Gain and Metabolic Abnormalities: A Systematic Review and Meta-Analysis · Lawrence A. Maayan · 2010 · 230 citations · Cited by this paper
  20. The interplay between mental health, ecological factors, and problematic smartphone use: a network analysis in adolescents with major depressive disorder · 2026 · Related
  21. Metabolic syndrome – a new definition and management guidelines A joint position paper by the Polish Society of Hypertension, Polish Society for the Treatment of Obesity, Polish Lipid Association, Polish Association for Study of Liver, Polish Society of Family Medicine, Polish Society of Lifestyle Medicine, Division of Prevention and Epidemiology Polish Cardiac Society, “Club 30” Polish Cardiac Society, and Division of Metabolic and Bariatric Surgery Society of Polish Surgeons · Piotr Dobrowolski · 2022 · 200 citations · Cited by this paper
  22. Influence of topiramate in the regulation of energy balance · Denis Richard · 2000 · 162 citations · Cited by this paper
  23. Review of the use of Topiramate for treatment of psychiatric disorders · Danilo Arnone · 2005 · 133 citations · Cited by this paper
  24. Role of Metformin for Weight Management in Patients Without Type 2 Diabetes · Alicia R Desilets · 2008 · 111 citations · Cited by this paper
  25. Topiramate for prevention of olanzapine associated weight gain and metabolic dysfunction in schizophrenia: A double-blind, placebo-controlled trial · Preeta Kaur Narula · 2010 · 107 citations · Cited by this paper
  26. Topiramate as an Adjuvant Treatment With Atypical Antipsychotics in Schizophrenic Patients Experiencing Weight Gain · Young‐Hoon Ko · 2005 · 105 citations · Cited by this paper
  27. Pharmacological treatment and therapeutic perspectives of metabolic syndrome · Soo Lim · 2014 · 91 citations · Cited by this paper
  28. Metformin for Weight Gain and Metabolic Abnormalities Associated With Antipsychotic Treatment · Wei Zheng · 2015 · 90 citations · Cited by this paper
  29. Topiramate and cognitive impairment: evidence and clinical implications · Marco Mula · 2012 · 84 citations · Cited by this paper
  30. Systematic Review and Meta-analysis of Pharmacological Interventions for Weight Gain from Antipsychotics and Mood Stabilizers · Jess G. Fiedorowicz · 2012 · 80 citations · Cited by this paper
  31. The effect of famotidine addition on olanzapine-induced weight gain in first-episode schizophrenia patients: a double-blind placebo-controlled pilot study · Michael Poyurovsky · 2003 · 67 citations · Cited by this paper
  32. Nizatidine treatment and its relationship with leptin levels in patients with olanzapine‐induced weight gain · Murad Atmaca · 2003 · 61 citations · Cited by this paper
  33. Metformin for the Prevention of Antipsychotic-Induced Weight Gain: Guideline Development and Consensus Validation · Aoife Carolan · 2024 · 58 citations · Cited by this paper
  34. Independent external validation of the QRISK3 cardiovascular disease risk prediction model using UK Biobank · Ruth E. Parsons · 2023 · 51 citations · Cited by this paper
  35. Comparison of Acute Followed by Maintenance ECT vs Clozapine on Psychopathology and Regional Cerebral Blood Flow in Treatment-Resistant Schizophrenia: A Randomized Controlled Trial · Biswa Ranjan Mishra · 2022 · 44 citations · Cited by this paper
  36. Topiramate and Metformin Are Effective Add-On Treatments in Controlling Antipsychotic-Induced Weight Gain: A Systematic Review and Network Meta-Analysis · Chuanjun Zhuo · 2018 · 40 citations · Cited by this paper
  37. Topiramate mitigates weight gain in antipsychotic-treated patients with schizophrenia: meta-analysis of randomised controlled trials · Kah Kheng Goh · 2018 · 39 citations · Cited by this paper
  38. Good Outcome in Young Adult Schizophrenia · Lawrence Kayton · 1973 · 37 citations · Cited by this paper
  39. Efficacy and tolerability of pharmacological interventions on metabolic disturbance induced by atypical antipsychotics in adults: A systematic review and network meta-analysis · Yewei Wang · 2021 · 34 citations · Cited by this paper

Source: OpenAlex (CC0)