Research map: Sodium-Glucose Cotransporter-2 Inhibitors in Valvular Heart Disease: From Mechanistic Insights to Clinical Application

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Papers in this map

  1. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction · John J.V. McMurray · 2019 · 7146 citations · Cited by this paper
  2. The Catheterization Laboratory: An Occupational Anachronism · 2026 · Related
  3. Cardiovascular and Renal Outcomes with Empagliflozin in Heart Failure · Milton Packer · 2020 · 5221 citations · Cited by this paper
  4. Percutaneous Mechanical Aspiration of Left-Sided Intracardiac Masses for Prohibitive Surgical Candidates: A Single-Center Experience · 2026 · Related
  5. Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients · Michael J. Mack · 2019 · 4901 citations · Cited by this paper
  6. Augmented Reality Ultrasound-Guided Vascular Access via Apple Vision Pro · 2026 · Related
  7. Empagliflozin in Heart Failure with a Preserved Ejection Fraction · Stefan D. Anker · 2021 · 4865 citations · Cited by this paper
  8. Balloon Rupture During Balloon-Expandable TAVR: Insights Into the Role of Calcium Distribution and Lesion Preparation From Two Cases · 2026 · Related
  9. Transcatheter Mitral-Valve Repair in Patients with Heart Failure · Gregg W. Stone · 2018 · 2990 citations · Cited by this paper
  10. Enhanced Radiation Protection Devices in Every Fluoroscopic Laboratory: A Call to Action · 2026 · Related
  11. Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction · Scott David Solomon · 2022 · 2871 citations · Cited by this paper
  12. A Hemodynamic Scoring System for Optimizing Transcatheter Arterialization of the Deep Veins in No-Option Patients With Chronic Limb-Threatening Ischemia · 2026 · Related
  13. The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease · Yun‐Hee Youm · 2015 · 2174 citations · Cited by this paper
  14. Evaluation and Treatment of Myocardial Bridging by Clinical Phenotype · 2026 · Related
  15. Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure · Deepak L. Bhatt · 2020 · 1873 citations · Cited by this paper
  16. Gender Disparities Among Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Mitral Valve Replacement Operators in the United States · 2026 · Related
  17. Right Ventricular Function in Cardiovascular Disease, Part II · François Haddad · 2008 · 1301 citations · Cited by this paper
  18. Artificial Intelligence–Derived Coronary Physiology Comes of Age—Promises, Precision, and Pragmatism in the Cath Lab · 2026 · Related
  19. Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients · Ele Ferrannini · 2014 · 1145 citations · Cited by this paper
  20. Pulmonary Embolism in the United States: A Report From the National PERT Consortium · 2026 · Related
  21. Targeting the unfolded protein response in disease · Claudio A. Hetz · 2013 · 921 citations · Cited by this paper
  22. Transcatheter Repair for Patients with Tricuspid Regurgitation · Paul Sorajja · 2023 · 917 citations · Cited by this paper
  23. Pathological Ventricular Remodeling · Jana S. Burchfield · 2013 · 774 citations · Cited by this paper
  24. Role of Oxidative Stress in Cardiac Hypertrophy and Remodeling · Eiki Takimoto · 2006 · 771 citations · Cited by this paper
  25. Empagliflozin decreases myocardial cytoplasmic Na+ through inhibition of the cardiac Na+/H+ exchanger in rats and rabbits · Antonius Baartscheer · 2016 · 671 citations · Cited by this paper
  26. Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts · Tsung‐Ming Lee · 2017 · 508 citations · Cited by this paper
  27. SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice · Liang Xu · 2017 · 507 citations · Cited by this paper
  28. Why do SGLT2 inhibitors reduce heart failure hospitalization? A differential volume regulation hypothesis · K. Melissa Hallow · 2017 · 490 citations · Cited by this paper
  29. Valvular Myofibroblast Activation by Transforming Growth Factor-β · Gennyne A. Walker · 2004 · 402 citations · Cited by this paper
  30. Effect of Empagliflozin on Erythropoietin Levels, Iron Stores, and Red Blood Cell Morphology in Patients With Type 2 Diabetes Mellitus and Coronary Artery Disease · C. David Mazer · 2019 · 370 citations · Cited by this paper
  31. Effect of Sodium‐Glucose Cotransport‐2 Inhibitors on Blood Pressure in People With Type 2 Diabetes Mellitus: A Systematic Review and Meta‐Analysis of 43 Randomized Control Trials With 22 528 Patients · Mohsen Mazidi · 2017 · 356 citations · Cited by this paper
  32. Cellular Mechanisms of Aortic Valve Calcification · Jane A. Leopold · 2012 · 262 citations · Cited by this paper
  33. Empagliflozin Reduces Ca/Calmodulin-Dependent Kinase II Activity in Isolated Ventricular Cardiomyocytes · Julian Mustroph · 2018 · 241 citations · Cited by this paper
  34. SGLT2 Inhibitor–Induced Sympathoinhibition · Lakshini Yasaswi Herat · 2020 · 237 citations · Cited by this paper
  35. Activation and Inhibition of Sodium-Hydrogen Exchanger Is a Mechanism That Links the Pathophysiology and Treatment of Diabetes Mellitus With That of Heart Failure · Milton Packer · 2017 · 232 citations · Cited by this paper
  36. Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF‐β/Smad signalling in type 2 diabetic rats · Jingjing Tian · 2021 · 213 citations · Cited by this paper
  37. The Acute Hemodynamic Effects of MitraClip Therapy · Robert James Siegel · 2011 · 203 citations · Cited by this paper
  38. Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload · Alexander Meyer · 2011 · 202 citations · Cited by this paper
  39. Empagliflozin Prevents Worsening of Cardiac Function in an Experimental Model of Pressure Overload-Induced Heart Failure · Nikole J. Byrne · 2017 · 176 citations · Cited by this paper

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