Research map: Metabolic diversity of tumor-infiltrating T cells as target for anti-immune therapeutics

Papers in this map

1. Hallmarks of Cancer: The Next Generation · Douglas Hanahan · 2011 · 67934 citations · Cited by this paper
2. Microbial metabolite-driven immune reprogramming in tumor immunotherapy: mechanisms and therapeutic perspectives · Yao Lu · 2025 · 32 citations · Cites this paper
3. HBO1 suppresses anti-tumor immunity of CD8⁺ T Cells in thyroid cancer by recruiting BRD4 to regulate VTCN1 expression · 2026 · Related
4. Metabolic support of tumour-infiltrating regulatory T cells by lactic acid · McLane J. Watson · 2021 · 1310 citations · Cited by this paper
5. Glycolysis inhibition-based breakdown of ferroptosis defenses to achieve ferroptosis and immune cascades for antitumor therapy · Nan Liu · 2025 · 9 citations · Cites this paper
6. Conserved minimal CD8 cytotoxic immune-state unit in an IL18R1-associated immune program in hepatocellular carcinoma · 2026 · Related
7. Lactate increases stemness of CD8 + T cells to augment anti-tumor immunity · Qiang Feng · 2022 · 429 citations · Cited by this paper
8. Activation-induced cytidine deaminase in tertiary lymphoid structures: dual roles and implications in cancer prognosis · Zhuangwei Lv · 2025 · 8 citations · Cites this paper
9. Impact of neck nodal yield on immune checkpoint inhibitor outcome after recurrence in head and neck squamous cell carcinoma · 2026 · Related
10. Combination of CAR‑T cell therapy and radiotherapy: Opportunities and challenges in solid tumors (Review) · Liqiang Zhong · 2023 · 44 citations · Cited by this paper
11. Metabolic reprogramming orchestrates an immunosuppressive microenvironment in anaplastic thyroid cancer: mechanisms and clinical perspectives · Jinkun Xia · 2026 · 2 citations · Cites this paper
12. Preclinical efficacy of iPSC-derived MUC1-targeted CAR-NK cells against esophageal squamous cell carcinoma · 2026 · Related
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14. Memory programming and new manufacturing paradigms in CAR-T cell therapy · Niloufar Mohammadkhani · 2026 · 1 citation · Cites this paper
15. Survival outcomes of conversion curative therapy following atezolizumab–bevacizumab in advanced hepatocellular carcinoma · 2026 · Related
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17. Comprehensive characterization of Fidgetin on tumor immune microenvironment evaluation and immunotherapy in human hepatocellular carcinoma · Longju Qi · 2024 · 1 citation · Cites this paper
18. Integrative single-cell and multi-omics analysis of ZBTB21-mediated serine metabolism in colorectal cancer: from metabolic reprogramming to immune microenvironment modulation · 2026 · Related
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20. Dynamic remodeling of the tumor immune microenvironment: immunometabolic regulatory networks of astragalus polysaccharides and astragaloside IV · Ziming Xu · 2026 · Cites this paper
21. Squeezing Treatment-Induced Metabolic Alterations in Melanoma Cells Are Accompanied by Impaired Cluster of Differentiation 8-Positive T Cell and Natural Killer Cell Antitumor Effector Functions · 2026 · Related
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23. Efficacy and safety of anti-PD-1 combined with IFN-α1b with or without anlotinib as the first-line therapy in patients with unresectable advanced melanoma: a real-world cohort study · 2026 · Related
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25. Spatially fractionated radiotherapy with PD-L1 blockade achieves superior antitumor efficacy and safety in a preclinical model of peritoneal metastasis · 2026 · Related
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