Research map: Programmed cell death in autoimmune diseases

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Papers in this map

  1. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death · Scott J. Dixon · 2012 · 19067 citations · Cited by this paper
  2. Rewiring immunometabolism in hepato-biliary-pancreatic cancers: Unraveling TME-mediated metabolic suppression and advancing next-generation immunotherapeutic approaches · 2026 · Related
  3. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 · Lorenzo Galluzzi · 2018 · 6767 citations · Cited by this paper
  4. Predicting the course: Real-world trajectories toward minimal disease activity in psoriatic arthritis · 2026 · Related
  5. Ferroptosis: molecular mechanisms and health implications · Daolin Tang · 2020 · 4378 citations · Cited by this paper
  6. The future of TCR-Treg therapies is renewables · 2026 · Related
  7. Metabolic regulation of gene expression by histone lactylation · Di Zhang · 2019 · 4375 citations · Cited by this paper
  8. Pathological reprogramming of innate immune cells drives resistance to biologics in inflammatory bowel diseases · 2026 · Related
  9. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition · Sebastian G. Doll · 2016 · 4318 citations · Cited by this paper
  10. The glucocorticoid dexamethasone inhibits HIF-1α stabilization and metabolic reprogramming in lipopolysaccharide-stimulated primary macrophages · 2023 · Related
  11. Sterile inflammation: sensing and reacting to damage · Grace Chen · 2010 · 3057 citations · Cited by this paper
  12. Chimeric Antigen Receptor T Cell Therapy in Systemic Lupus Erythematosus: Mechanisms, Clinical Advances, and Future Directions a Comprehensive Review · 2025 · Related
  13. Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion · Wanting He · 2015 · 2585 citations · Cited by this paper
  14. IL-1 family cytokines in inflammation and immunity · 2025 · Related
  15. ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation · Kathryn E. Wellen · 2009 · 2334 citations · Cited by this paper
  16. Therapeutic Potential of Nanocarriers in the Management of Rheumatoid Arthritis · 2024 · Related
  17. Necroptosis, pyroptosis and apoptosis: an intricate game of cell death · Damien Bertheloot · 2021 · 2225 citations · Cited by this paper
  18. Metabolic regulatory nodes of the inflammasome and inflammatory cell death · 2026 · Related
  19. The cell biology of ferroptosis · Scott J. Dixon · 2024 · 1477 citations · Cited by this paper
  20. Endosome traffic in rheumatic diseases: mechanistic insights and therapeutic opportunities · 2025 · Related
  21. FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation · Jun Jacob Hu · 2020 · 1147 citations · Cited by this paper
  22. Apoptosis and Clearance of Apoptotic Cells · Shigekazu Nagata · 2018 · 1143 citations · Cited by this paper
  23. Autophagy: Regulator of cell death · ShiZuo Liu · 2023 · 1108 citations · Cited by this paper
  24. On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death · Omkar Zilka · 2017 · 1066 citations · Cited by this paper
  25. Fas ligand mediates activation-induced cell death in human T lymphocytes. · Mark R. Alderson · 1995 · 953 citations · Cited by this paper
  26. Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK · Nathalie Conrad · 2023 · 881 citations · Cited by this paper
  27. Autophagy-dependent cell death · Donna Denton · 2018 · 791 citations · Cited by this paper
  28. BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes · Philippe Bouillet · 2002 · 782 citations · Cited by this paper
  29. Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation · Valerie A. Gerriets · 2014 · 741 citations · Cited by this paper
  30. IL-33: an alarmin cytokine with crucial roles in innate immunity, inflammation and allergy · Corinne Cayrol · 2014 · 721 citations · Cited by this paper
  31. Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects · Qin Ru · 2024 · 675 citations · Cited by this paper
  32. Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor · Samantha A. Scott · 2020 · 672 citations · Cited by this paper
  33. The PANoptosome: A Deadly Protein Complex Driving Pyroptosis, Apoptosis, and Necroptosis (PANoptosis) · Parimal Samir · 2020 · 562 citations · Cited by this paper
  34. Targeting immunogenic cell stress and death for cancer therapy · Lorenzo Galluzzi · 2024 · 532 citations · Cited by this paper
  35. Glutathione peroxidase 4–regulated neutrophil ferroptosis induces systemic autoimmunity · Pengchong Li · 2021 · 472 citations · Cited by this paper
  36. Metabolic and epigenetic regulation of T-cell exhaustion · Fabien Franco · 2020 · 464 citations · Cited by this paper
  37. Cell death in the gut epithelium and implications for chronic inflammation · Jay V. Patankar · 2020 · 436 citations · Cited by this paper
  38. ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis · Rajendra Karki · 2021 · 434 citations · Cited by this paper
  39. N ‐acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: A randomized, double‐blind, placebo‐controlled trial · Zhi‐Wei Lai · 2012 · 425 citations · Cited by this paper

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