Research map: Synonymous codon-optimized multiplex qPCR for simultaneous detection of Helicobacter pylori and precise drug resistance profiling in infected individuals

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  1. Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report · Peter Malfertheiner · 2016 · 2970 citations · Cited by this paper
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  11. Preponderance of synonymous changes as evidence for the neutral theory of molecular evolution · MOTOO KIMURA · 1977 · 735 citations · Cited by this paper
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  17. Epidemiology ofHelicobacter pyloriInfection · Leonardo Henry Eusebi · 2014 · 520 citations · Cited by this paper
  18. A comparative performance evaluation of the VIDAS cytomegalovirus (CMV) interferon-gamma release assay (IGRA) and T-SPOT CMV for measuring CMV-specific T-cell responses in allogeneic hematopoietic stem cell transplant recipients receiving letermovir prophylaxis · 2026 · Related
  19. Exposing synonymous mutations · Ryan Hunt · 2014 · 408 citations · Cited by this paper
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  21. ACG Clinical Guideline: Treatment of Helicobacter pylori Infection · William D. Chey · 2024 · 393 citations · Cited by this paper
  22. Helicobacter pylori evolution and phenotypic diversification in a changing host · Sebastian Suerbaum · 2007 · 388 citations · Cited by this paper
  23. Nonrandom utilization of codon pairs in Escherichia coli. · George A. Gutman · 1989 · 270 citations · Cited by this paper
  24. A pan-cancer analysis of synonymous mutations · Yogita Sharma · 2019 · 253 citations · Cited by this paper
  25. Nucleotide sequence of the gyrA gene and characterization of ciprofloxacin-resistant mutants of Helicobacter pylori · Richard A. Moore · 1995 · 174 citations · Cited by this paper
  26. Codon Pair Utilization Biases Influence Translational Elongation Step Times · Becky Irwin · 1995 · 173 citations · Cited by this paper
  27. Within-host evolution of Helicobacter pylori shaped by niche-specific adaptation, intragastric migrations and selective sweeps · Florent Ailloud · 2019 · 161 citations · Cited by this paper
  28. Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis · Tzu‐Chan Hong · 2023 · 156 citations · Cited by this paper
  29. Synonymous mutations make dramatic contributions to fitness when growth is limited by a weak-link enzyme · JohnCarlo Kristofich · 2018 · 131 citations · Cited by this paper
  30. Absence of translationally selected synonymous codon usage bias in Helicobacter pylori · Bénédicte Lafay · 2000 · 101 citations · Cited by this paper
  31. Discovery of novel mutations for clarithromycin resistance in Helicobacter pylori by using next-generation sequencing · Trần Thanh Bình · 2014 · 84 citations · Cited by this paper
  32. Primary and secondary antibiotic resistance of Helicobacter pylori in Korea from 2003 to 2018 · Ju Yup Lee · 2019 · 75 citations · Cited by this paper
  33. Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication · Toshihiro Nishizawa · 2009 · 63 citations · Cited by this paper
  34. Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase · Mark P. Zwart · 2018 · 59 citations · Cited by this paper
  35. Evaluation of multiplex ARMS-PCR for detection of Helicobacter pylori mutations conferring resistance to clarithromycin and levofloxacin · Yangxia Li · 2020 · 49 citations · Cited by this paper
  36. Helicobacter pylori resistance to current therapies · Sinéad M. Smith · 2018 · 46 citations · Cited by this paper
  37. Clarithromycin Resistance in Helicobacter pylori Strains Isolated from French Children: Prevalence of the Different Mutations and Coexistence of Clones Harboring Two Different Mutations in the Same Biopsy · Josette Raymond · 2007 · 45 citations · Cited by this paper
  38. Drug Resistance Patterns of Commonly Used Antibiotics for the Treatment of Helicobacter pylori Infection among South Asian Countries: A Systematic Review and Meta-Analysis · Abhigan Babu Shrestha · 2023 · 35 citations · Cited by this paper
  39. Antibacterial resistance and the success of tailored triple therapy in Helicobacter pylori strains isolated from Slovenian children · Tita Butenko · 2017 · 31 citations · Cited by this paper

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