Research map: Ultrasound-targeted nanodroplets destruction activates CAF_Pi16-CCL7 signalling to enhance NKG2D expression and overcome ICB resistance in MSS CRC

Back to the article

Papers in this map

  1. Integrating single-cell transcriptomic data across different conditions, technologies, and species · Andrew W. Butler · 2018 · 15128 citations · Cited by this paper
  2. Commentary regarding “Electroacupuncture combined with fruquintinib and sintilimab in microsatellite-stable metastatic colorectal cancer: A phase II study” · 2026 · Related
  3. SCANPY: large-scale single-cell gene expression data analysis · F. Alexander Wolf · 2018 · 9933 citations · Cited by this paper
  4. Optimized L1CAM-CAR T cells enhance activity against moderate-antigen-density rhabdomyosarcoma models · 2026 · Related
  5. The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth · Karin E. de Visser · 2023 · 4018 citations · Cited by this paper
  6. VG161 oncolytic virus remodels the tumor microenvironment by expanding CD3+ macrophages and enhancing antitumor immunity · 2026 · Related
  7. Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer · Thierry André · 2020 · 3141 citations · Cited by this paper
  8. GSN liquid-liquid phase separation induces PANoptosis by inhibiting YAP-dependent glycolysis to alleviate the progression of clear cell renal cell carcinoma · 2026 · Related
  9. Clinical and therapeutic relevance of cancer-associated fibroblasts · Yang Chen · 2021 · 1320 citations · Cited by this paper
  10. Mechano-activation of osteocytic connexin hemichannels prime microenvironment in suppressing breast cancer bone metastasis · 2026 · Related
  11. Cross-tissue organization of the fibroblast lineage · Matthew B. Buechler · 2021 · 1172 citations · Cited by this paper
  12. The m6A epitranscriptome in cancer therapy resistance: From cellular plasticity and metabolic rewiring to immune escape and therapeutic targeting · 2026 · Related
  13. Bulk tissue cell type deconvolution with multi-subject single-cell expression reference · Xuran Wang · 2019 · 1043 citations · Cited by this paper
  14. Elevated FN14 expression promotes proliferation, chemoresistance, and impairment of differentiation in rhabdomyosarcoma · 2026 · Related
  15. Physical traits of cancer · Hadi Tavakoli Nia · 2020 · 879 citations · Cited by this paper
  16. Targeting MDA-9/syntenin-1 (SDCBP) as a strategy to eliminate head and neck squamous cell carcinoma stem cells · 2026 · Related
  17. Design and Analysis of Single-Cell Sequencing Experiments · Dominic Grün · 2015 · 588 citations · Cited by this paper
  18. Antibody-drug conjugates against multidrug-resistant cancers: Biomarker-guided patient selection, payload engineering, linker chemistry, and bystander effects · 2026 · Related
  19. MHC Class I Downregulation in Cancer: Underlying Mechanisms and Potential Targets for Cancer Immunotherapy · Annelisa M. Cornel · 2020 · 479 citations · Cited by this paper
  20. Immunotherapy-based combination remodels the immunosuppressive microenvironment and enhances efficacy in advanced SMARCA4-deficient non-small cell lung cancer · 2026 · Related
  21. Applications of single-cell RNA sequencing in drug discovery and development · Bram Van de Sande · 2023 · 457 citations · Cited by this paper
  22. Insights Gained from Single-Cell Analysis of Immune Cells in the Tumor Microenvironment · Xianwen Ren · 2021 · 390 citations · Cited by this paper
  23. CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor · Guiqi Zhu · 2023 · 342 citations · Cited by this paper
  24. Ultrasound and microbubble mediated therapeutic delivery: Underlying mechanisms and future outlook · Sayan Mullick Chowdhury · 2020 · 292 citations · Cited by this paper
  25. Revolutionizing immunology with single-cell RNA sequencing · Haide Chen · 2019 · 258 citations · Cited by this paper
  26. Activation and modulation of the AGEs-RAGE axis: Implications for inflammatory pathologies and therapeutic interventions – A review · Mengzhou Zhou · 2024 · 251 citations · Cited by this paper
  27. 7th International Conference on Nanomaterials and Biomaterials (ICNB) and 5th Asia Conference on Material and Manufacturing Technology (ACMMT) · Steven Y. Liang · 2024 · 227 citations · Cited by this paper
  28. Population health and regional variations of disease burden in Japan, 1990–2015: a systematic subnational analysis for the Global Burden of Disease Study 2015 · Shuhei Nomura · 2017 · 224 citations · Cited by this paper
  29. Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery · Joke Deprez · 2021 · 213 citations · Cited by this paper
  30. Manipulation of Mitophagy by “All-in-One” nanosensitizer augments sonodynamic glioma therapy · Fei Qu · 2019 · 193 citations · Cited by this paper
  31. Mismatch Repair-Deficient Colorectal Cancer: Building on Checkpoint Blockade · Zhaohui Jin · 2022 · 182 citations · Cited by this paper
  32. Radiotherapy remodels the tumor microenvironment for enhancing immunotherapeutic sensitivity · Senbo Liu · 2023 · 162 citations · Cited by this paper
  33. Image-guided, targeted and triggered drug delivery to tumors using polymer-based microbubbles · Stanley Fokong · 2012 · 158 citations · Cited by this paper
  34. CD8+ T cells maintain killing of MHC-I-negative tumor cells through the NKG2D–NKG2DL axis · Emily Lerner · 2023 · 142 citations · Cited by this paper
  35. Chemotherapy- and radiotherapy-induced intestinal damage is regulated by intestinal trefoil factor · Paul L. Beck · 2004 · 131 citations · Cited by this paper
  36. Ultrasound-responsive microbubbles and nanodroplets: A pathway to targeted drug delivery · Gazendra Shakya · 2024 · 126 citations · Cited by this paper
  37. Ultrasonic gene and drug delivery to the cardiovascular system · Christian R. Mayer · 2008 · 105 citations · Cited by this paper
  38. Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer · Chaofan Liu · 2023 · 97 citations · Cited by this paper
  39. Ultrasound-targeted microbubble destruction remodels tumour microenvironment to improve immunotherapeutic effect · Senbo Liu · 2022 · 96 citations · Cited by this paper

Source: OpenAlex (CC0)