Research map: The role of ECM-PIEZO1-axis-mediated mechanosensation in the central nervous system

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  1. Neuropathological stageing of Alzheimer-related changes · Heiko Braak · 1991 · 16633 citations · Cited by this paper
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  23. Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity · Angel Gabriel Alpuche-Solis · 2019 · 707 citations · Cited by this paper
  24. Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing · Hamza Atcha · 2021 · 640 citations · Cited by this paper
  25. Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation · Stephen A. Back · 2005 · 616 citations · Cited by this paper
  26. Niche stiffness underlies the ageing of central nervous system progenitor cells · Michael Segel · 2019 · 563 citations · Cited by this paper
  27. Architecture of the mammalian mechanosensitive Piezo1 channel · Jingpeng Ge · 2015 · 546 citations · Cited by this paper
  28. Basement membrane and blood–brain barrier · Lingling Xu · 2018 · 362 citations · Cited by this paper
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  30. Oxidative Stress Increases Blood–Brain Barrier Permeability and Induces Alterations in Occludin during Hypoxia–Reoxygenation · Jeffrey J. Lochhead · 2010 · 334 citations · Cited by this paper
  31. Microglia facilitate loss of perineuronal nets in the Alzheimer's disease brain · Joshua D. Crapser · 2020 · 300 citations · Cited by this paper
  32. TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection · Jing Geng · 2021 · 292 citations · Cited by this paper
  33. Mechanisms of mechanotransduction and physiological roles of PIEZO channels · Bailong Xiao · 2024 · 291 citations · Cited by this paper
  34. The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration · Yuanquan Song · 2019 · 221 citations · Cited by this paper
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  36. Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage · Mark A. Petersen · 2017 · 209 citations · Cited by this paper
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  38. Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease · Jin Hu · 2022 · 200 citations · Cited by this paper
  39. The extracellular matrix as modifier of neuroinflammation and remyelination in multiple sclerosis · Samira Ghorbani · 2021 · 193 citations · Cited by this paper

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