Research map: Local Recurrence After Pancreatic Cancer Resection: A Multidisciplinary Review of Risk Factors and Potential Causes, Diagnostic Innovations, Emerging Therapeutic Frontiers, and Prevention Strategies

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  1. Preoperative Chemoradiotherapy Versus Immediate Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Results of the Dutch Randomized Phase III PREOPANC Trial · Eva Versteijne · 2020 · 1102 citations · Cited by this paper
  2. Revolutionizing Breast Cancer Therapeutics: Intersecting Frontiers of Precision Medicine, Nanotechnology, and Drug Delivery Innovations · 2025 · Related
  3. Cytokeratin-Positive Cells in the Bone Marrow and Survival of Patients with Stage I, II, or III Breast Cancer · Stephan Braun · 2000 · 935 citations · Cited by this paper
  4. Cardiotoxicity of Targeted Therapies in Hematologic Malignancies: From Molecular Mechanisms to Clinical Management · 2026 · Related
  5. Patterns, Timing, and Predictors of Recurrence Following Pancreatectomy for Pancreatic Ductal Adenocarcinoma · Vincent P. Groot · 2017 · 774 citations · Cited by this paper
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  7. Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patients · Fritz Lindemann · 1992 · 553 citations · Cited by this paper
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  9. Pancreatic cancer · Thomas F. Stoop · 2025 · 456 citations · Cited by this paper
  10. Updates on Therapy Options in Fit and Unfit Patients with Newly Diagnosed AML · 2025 · Related
  11. Tumour budding in solid cancers · Alessandro Lugli · 2020 · 380 citations · Cited by this paper
  12. Transforming a Roadblock into a Roadmap: Evolving HFSR Management From Adverse Event to Efficacy Biomarker · 2026 · Related
  13. Five-Year Outcomes of FOLFIRINOX vs Gemcitabine as Adjuvant Therapy for Pancreatic Cancer · Thierry Conroy · 2022 · 347 citations · Cited by this paper
  14. The Use of Targeted Therapy in Pediatric Acute Lymphoblastic Leukemia: Exploring Novel Approaches and Emerging Therapies · 2026 · Related
  15. RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer · Zachary M. Sethna · 2025 · 308 citations · Cited by this paper
  16. Advanced Mucosal Melanoma Therapies: Current Status and Future Directions · 2026 · Related
  17. Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma · Zhi Rong Qian · 2017 · 277 citations · Cited by this paper
  18. Research Priorities and Future Directions in Cardio-Oncology · 2026 · Related
  19. Impact of resection margin status on recurrence and survival in pancreatic cancer surgery · Willemieke S. F. J. Tummers · 2019 · 229 citations · Cited by this paper
  20. Role of Troponins in CardioOncology · 2026 · Related
  21. Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer · Chiara Falcomatà · 2023 · 205 citations · Cited by this paper
  22. Perineural Invasion Reprograms the Immune Microenvironment through Cholinergic Signaling in Pancreatic Ductal Adenocarcinoma · Minwei Yang · 2020 · 200 citations · Cited by this paper
  23. Composition, Spatial Characteristics, and Prognostic Significance of Myeloid Cell Infiltration in Pancreatic Cancer · Sara A. Väyrynen · 2020 · 165 citations · Cited by this paper
  24. Percutaneous Irreversible Electroporation in Locally Advanced and Recurrent Pancreatic Cancer (PANFIRE-2): A Multicenter, Prospective, Single-Arm, Phase II Study · Alette H. Ruarus · 2019 · 161 citations · Cited by this paper
  25. Perioperative Activation of Disseminated Tumor Cells in Bone Marrow of Patients With Prostate Cancer · Dorothea Weckermann · 2009 · 159 citations · Cited by this paper
  26. Arterial Resection in Pancreatic Cancer Surgery · Martin Loos · 2020 · 148 citations · Cited by this paper
  27. Cellular and molecular mechanisms of perineural invasion of pancreatic ductal adenocarcinoma · Jingbo Li · 2021 · 140 citations · Cited by this paper
  28. Characterization of single neurons reprogrammed by pancreatic cancer · Vera Thiel · 2025 · 137 citations · Cited by this paper
  29. Impact of tumor‐associated macrophages on invasive ductal carcinoma of the pancreas head · Kiyoshi YOSHIKAWA · 2012 · 135 citations · Cited by this paper
  30. Utility of Contrast-Enhanced FDG-PET/CT in the Clinical Management of Pancreatic Cancer · Akinori Asagi · 2012 · 133 citations · Cited by this paper
  31. The Impact of Neural Invasion Severity in Gastrointestinal Malignancies · Florian Liebl · 2014 · 132 citations · Cited by this paper
  32. The Evolutionary Origins of Recurrent Pancreatic Cancer · Hitomi Sakamoto · 2020 · 132 citations · Cited by this paper
  33. Re-resection for Isolated Local Recurrence of Pancreatic Cancer is Feasible, Safe, and Associated with Encouraging Survival · Oliver Strobel · 2012 · 131 citations · Cited by this paper
  34. Clinical Impact of Neoadjuvant Chemotherapy and Chemoradiotherapy in Borderline Resectable Pancreatic Cancer: Analysis of 884 Patients at Facilities Specializing in Pancreatic Surgery · Yuichi Nagakawa · 2019 · 123 citations · Cited by this paper
  35. Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer · Jad I. Belle · 2024 · 117 citations · Cited by this paper
  36. Validation of at least 1 mm as cut-off for resection margins for pancreatic adenocarcinoma of the body and tail · Thomas Hank · 2018 · 110 citations · Cited by this paper
  37. Margin status, recurrence pattern, and prognosis after resection of pancreatic cancer · Teiichi Sugiura · 2013 · 97 citations · Cited by this paper
  38. Administration of Gemcitabine After Pancreatic Tumor Resection in Mice Induces an Antitumor Immune Response Mediated by Natural Killer Cells · Engin Gürlevik · 2016 · 92 citations · Cited by this paper
  39. Tumor-neuroglia interaction promotes pancreatic cancer metastasis · Dan Su · 2020 · 80 citations · Cited by this paper

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