Research map: Modulation of pancreatic β-cell function by adaptogens: Emerging evidence and integrative therapeutic potential

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  1. The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation · Peter Walter · 2011 · 6142 citations · Cited by this paper
  2. Novel oligomeric caffeoyl derivatives and acylated flavone glycosides from Satureja nervosa Desf.: Chemical characterisation, structure-activity relationships, and multi-target bioactivity in Caenorhabditis elegans disease models · 2026 · Related
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  7. Influence of Piperine on the Pharmacokinetics of Curcumin in Animals and Human Volunteers · Guido Shoba · 1998 · 1973 citations · Cited by this paper
  8. Integrating LC-MS and network pharmacology to uncover the mechanism of antidepressant effects of Illigera aromatica ethanol extract in rodent models · 2026 · Related
  9. Ginseng pharmacology · Anoja S. Attele · 1999 · 1871 citations · Cited by this paper
  10. Exploring the pro-angiogenic constituents of Lagopsis supina and their mechanisms via transcriptome analysis, molecular docking and RT-qPCR validation · 2026 · Related
  11. Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes · Miriam Cnop · 2005 · 1500 citations · Cited by this paper
  12. Antifungal activity of green propolis extract against planktonic cells and biofilms of Trichosporon asahii clinical isolates · 2026 · Related
  13. Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure · Chutima Talchai · 2012 · 1432 citations · Cited by this paper
  14. Monoterpene indole alkaloids from the seeds of Strychnos nux-vomica L. with anti-rheumatoid arthritis activity · 2026 · Related
  15. Dipeptidyl‐peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon‐like peptide‐1(7–36)amide, peptide histidine methionine and is responsible for their degradation in human serum · Rolf Mentlein · 1993 · 1170 citations · Cited by this paper
  16. Hispidin-enriched Sanhuangporus sanghuang ethanolic extract: A novel GLP-1 inducer with non-mutagenic properties · 2026 · Related
  17. Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction · Vincent Poitout · 2008 · 1092 citations · Cited by this paper
  18. Investigating the mechanism of action of the herbal pair Schizonepeta tenuifolia Briq. and Saposhnikovia Divaricata and their active components in common allergic skin diseases · 2026 · Related
  19. Beta Cell Dysfunction and Insulin Resistance · Marlon E. Cerf · 2013 · 978 citations · Cited by this paper
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  21. Diabetes Mellitus and the β Cell: The Last Ten Years · Frances Mary Ashcroft · 2012 · 917 citations · Cited by this paper
  22. Pancreatic β-cells in type 1 and type 2 diabetes mellitus: different pathways to failure · Decio Laks Eizirik · 2020 · 887 citations · Cited by this paper
  23. Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men · Patrik Rorsman · 2017 · 819 citations · Cited by this paper
  24. Curcumin Extract for Prevention of Type 2 Diabetes · Somlak Chuengsamarn · 2012 · 640 citations · Cited by this paper
  25. Rosenroot (Rhodiola rosea): Traditional use, chemical composition, pharmacology and clinical efficacy · Alexander Panossian · 2010 · 604 citations · Cited by this paper
  26. Initiation and execution of lipotoxic ER stress in pancreatic β-cells · Daniel Andrade Cunha · 2008 · 598 citations · Cited by this paper
  27. The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes · Donalyn Scheuner · 2008 · 541 citations · Cited by this paper
  28. Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes · Gary A. Herman · 2006 · 499 citations · Cited by this paper
  29. Critical Role of cAMP-GEFII·Rim2 Complex in Incretin-potentiated Insulin Secretion · Yasushige Kashima · 2001 · 384 citations · Cited by this paper
  30. Curcumin Content of Turmeric and Curry Powders · Reema Tayyem · 2006 · 374 citations · Cited by this paper
  31. Pharmacologic overview of Withania somnifera, the Indian Ginseng · Nawab John Dar · 2015 · 373 citations · Cited by this paper
  32. A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults · K. Chandrasekhar · 2012 · 354 citations · Cited by this paper
  33. American Ginseng (Panax quinquefolius L) Reduces Postprandial Glycemia in Nondiabetic Subjects and Subjects With Type 2 Diabetes Mellitus · Vladimir V.V. Vuksan · 2000 · 353 citations · Cited by this paper
  34. Pancreatic β-cell identity, glucose sensing and the control of insulin secretion · Guy A. Rutter · 2015 · 348 citations · Cited by this paper
  35. Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐ and aging‐related diseases · Alexander Panossian · 2020 · 345 citations · Cited by this paper
  36. Variability in commercial ginseng products: an analysis of 25 preparations · Martha R. Harkey · 2001 · 323 citations · Cited by this paper
  37. The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes · Christina Schiborr · 2014 · 321 citations · Cited by this paper
  38. Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis · Ping Zhou · 2019 · 319 citations · Cited by this paper
  39. Withaferin A Strongly Elicits IκB Kinase β Hyperphosphorylation Concomitant with Potent Inhibition of Its Kinase Activity · Mary Kaileh · 2006 · 302 citations · Cited by this paper

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