Research map: Safety, feasibility, and palliative benefit of HIFU combined with PD-1 inhibitors for elderly patients with advanced pancreatic cancer: a real-world retrospective study

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  1. Relaxing the Rule of Ten Events per Variable in Logistic and Cox Regression · Eric Vittinghoff · 2006 · 4366 citations · Cited by this paper
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  13. PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance · Vivek Verma · 2019 · 342 citations · Cited by this paper
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  19. High-Intensity Focused Ultrasound (HIFU) Triggers Immune Sensitization of Refractory Murine Neuroblastoma to Checkpoint Inhibitor Therapy · Avinash Eranki · 2019 · 178 citations · Cited by this paper
  20. Randomized Phase II Study of Nivolumab With or Without Ipilimumab Combined With Stereotactic Body Radiotherapy for Refractory Metastatic Pancreatic Cancer (CheckPAC) · Inna Markovna Chen · 2022 · 114 citations · Cited by this paper
  21. Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer · Brett Z. Fite · 2021 · 95 citations · Cited by this paper
  22. Analgesic effect of high intensity focused ultrasound therapy for unresectable pancreatic cancer · Kun Wang · 2011 · 88 citations · Cited by this paper
  23. Immunomodulation and targeted drug delivery with high intensity focused ultrasound (HIFU): Principles and mechanisms · Harshini K. Ashar · 2023 · 81 citations · Cited by this paper
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  25. Tumor immune microenvironment in pancreatic ductal adenocarcinoma revisited – Exploring the “Space” · Konstantin Bräutigam · 2025 · 53 citations · Cited by this paper
  26. The tumour microenvironment in pancreatic cancer — new clinical challenges, but more opportunities · Heng‐Chung Kung · 2025 · 53 citations · Cited by this paper
  27. HIFU is safe, effective, and feasible in pancreatic cancer patients: a monocentric retrospective study among 523 patients · Zhouyu Ning · 2019 · 52 citations · Cited by this paper
  28. Comparative Efficacy and Safety of PD-1/PD-L1 Inhibitors for Patients with Solid Tumors: A Systematic Review and Bayesian Network Meta-analysis · Qingyuan Huang · 2020 · 45 citations · Cited by this paper
  29. Magic bubbles: utilizing histotripsy to modulate the tumor microenvironment and improve systemic anti-tumor immune responses · Khan Muhammad Imran · 2023 · 44 citations · Cited by this paper
  30. Advances in pancreatic cancer early diagnosis, prevention, and treatment: The past, the present, and the future · Alessandro Mannucci · 2025 · 38 citations · Cited by this paper
  31. Improving quality of life in pancreatic cancer patients following high-intensity focused ultrasound (HIFU) in two European centers · Milka Marinova · 2021 · 37 citations · Cited by this paper
  32. Prognostic and clinical significance of modified glasgow prognostic score in pancreatic cancer: a meta-analysis of 4,629 patients · Dongdong Wu · 2021 · 33 citations · Cited by this paper
  33. Network Meta-analysis Comparing Efficacy, Safety and Tolerability of Anti-PD-1/PD-L1 Antibodies in Solid Cancers · Laith Al-Showbaki · 2021 · 17 citations · Cited by this paper
  34. Pancreatic adenocarcinoma third line systemic treatments: a retrospective cohort study · Anna Gueiderikh · 2024 · 14 citations · Cited by this paper
  35. State of the Art of Immune Checkpoint Inhibitors in Unresectable Pancreatic Cancer: A Comprehensive Systematic Review · Elena Orlandi · 2025 · 11 citations · Cited by this paper
  36. Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer · James Wang · 2022 · 9 citations · Cited by this paper
  37. Analysis of the results of high-intensity focused ultrasound for patients with advanced pancreatic cancer · Chuan Qian · 2023 · 8 citations · Cited by this paper
  38. Scoring model with serum albumin and CA19-9 for metastatic pancreatic cancer in second-line treatment: results from the NAPOLEON study · Azusa Komori · 2023 · 5 citations · Cited by this paper
  39. High-Intensity Focused Ultrasound (HIFU) in Pancreatic Cancer-Related Pain: Current Evidence and Future Directions · Ying Liu · 2025 · 3 citations · Cited by this paper

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