Research map: John Cunningham Virus and Colorectal Carcinogenesis: Current Evidence, Molecular Mechanisms, and Unresolved Controversies

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Papers in this map

  1. Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis · Stephen J. Gaudino · 2019 · 306 citations · Cited by this paper
  2. Insights Into Highly Associated Co‐Factors on HPV‐Related Cervical Cancer · 2026 · Related
  3. JC virus DNA is present in the mucosa of the human colon and in colorectal cancers · Luigi Laghi · 1999 · 247 citations · Cited by this paper
  4. From Surge to Stability: Navigating MPOX Epidemics Across the Globe With Genomic Insights, Paving the Way for Effective Management Plan · 2026 · Related
  5. JC virus DNA sequences are frequently present in the human upper and lower gastrointestinal tract · Luigi Ricciardiello · 2000 · 159 citations · Cited by this paper
  6. The Burden of HPV35 in African Cervical Pathologies: Prevalence, Contributing Factors, and Vaccine Prospects · 2026 · Related
  7. Prevalence and association of pks+ Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia · Thevambiga Iyadorai · 2020 · 119 citations · Cited by this paper
  8. Human Sapovirus in the Post‐Rotavirus Vaccine Era: From an Overlooked Gastroenteritis Pathogen to a Target for Precision Surveillance · 2026 · Related
  9. Identification of three new JC virus proteins generated by alternative splicing of the early viral mRNA · Pamela W. Trowbridge · 1995 · 109 citations · Cited by this paper
  10. Possible Effects of C‐Reactive Protein in the Central Nervous System During Venezuelan Equine Encephalitis Virus Infection · 2026 · Related
  11. Association of JC Virus T-Antigen Expression With the Methylator Phenotype in Sporadic Colorectal Cancers · Ajay Goel · 2006 · 108 citations · Cited by this paper
  12. Synergistic Oncogenesis Cooperative Role of Epstein Barr Virus and Human Papillomavirus in Cancer Progression · 2026 · Related
  13. Liquid Biopsy: An Evolving Paradigm for Non-invasive Disease Diagnosis and Monitoring in Medicine · Kanishk K Adhit · 2023 · 94 citations · Cited by this paper
  14. Potential Relationship Between Cytomegalovirus and Cardiovascular Disease: Evidence From Observational Studies · 2026 · Related
  15. Large T Antigen Promotes JC Virus Replication in G2-arrested Cells by Inducing ATM- and ATR-mediated G2 Checkpoint Signaling · Yasuko Orba · 2009 · 83 citations · Cited by this paper
  16. Oncovirus‐Driven Endothelial Plasticity: Endothelial‐to‐Mesenchymal Transition as a Hijacked Pathway in Oncoviral Cardiovascular Pathogenesis · 2026 · Related
  17. The Association of Microbiome Dysbiosis With Colorectal Cancer · Artem Artemev · 2022 · 76 citations · Cited by this paper
  18. Kyasanur Forest Disease: Advances in Experimental Animal Models, Immune Assays, and Challenges in Vaccine Development · 2026 · Related
  19. Oncogenic T‐antigen of JC virus is present frequently in human gastric cancers · Sung Kwan Shin · 2006 · 67 citations · Cited by this paper
  20. Qualitative Modulation of Pattern Recognition Receptor Sensing in Human Oncoviral Infections: Shared and Virus‐Specific Innate Immune Strategies · 2026 · Related
  21. Activation of c-Myc and Cyclin D1 by JCV T-Antigen and β-Catenin in Colon Cancer · Michael J. Ripple · 2014 · 60 citations · Cited by this paper
  22. JC Virus T-Antigen in Colorectal Cancer Is Associated with p53 Expression and Chromosomal Instability, Independent of CpG Island Methylator Phenotype · Katsuhiko Nosho · 2009 · 59 citations · Cited by this paper
  23. JC virus T' proteins encoded by alternatively spliced early mRNAs enhance T antigen-mediated viral DNA replication in human cells · Cindy Prins · 2001 · 58 citations · Cited by this paper
  24. Prevalence of JC Virus in Chinese Patients with Colorectal Cancer · Xiaozhou Mou · 2012 · 55 citations · Cited by this paper
  25. JC Virus Mediates Invasion and Migration in Colorectal Metastasis · Alexander Link · 2009 · 50 citations · Cited by this paper
  26. Viral variant nucleotide sequences help expose leukocytic positioning in the JC virus pathway to the CNS · Peter N. Jensen · 1999 · 49 citations · Cited by this paper
  27. Human Polyomavirus JCPyV and Its Role in Progressive Multifocal Leukoencephalopathy and Oncogenesis · Luis Del Valle · 2019 · 34 citations · Cited by this paper
  28. Association between JC virus and colorectal cancer: systematic review and meta-analysis · Rasoul Shavaleh · 2019 · 30 citations · Cited by this paper
  29. The oncogenic roles of JC polyomavirus in cancer · Hua‐chuan Zheng · 2022 · 25 citations · Cited by this paper
  30. Exploring the role of NCCR variation on JC polyomavirus expression from dual reporter minicircles · Anne-Sophie L’Honneur · 2018 · 22 citations · Cited by this paper
  31. JC Virus Infection A Cause of Colorectal Cancer? · Dana E. M. Rollison · 2010 · 21 citations · Cited by this paper
  32. Development of an efficient bi-directional promoter with tripartite enhancer employing three viral promoters · Sunita Patro · 2012 · 19 citations · Cited by this paper
  33. Prevalence of JC and BK viruses in Patients with Colorectal Cancer: A Systematic Review and Meta- Analysis · Hamid Reza Shoraka · 2020 · 18 citations · Cited by this paper
  34. Pulmonary tumors associated with the JC virus T-antigen in a transgenic mouse model · Akira Noguchi · 2013 · 16 citations · Cited by this paper
  35. The conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigens · Ping An · 2015 · 15 citations · Cited by this paper
  36. Oncogenic potential of Campylobacter infection in the gastrointestinal tract: narrative review · Ikuko Kato · 2023 · 15 citations · Cited by this paper
  37. Multiple Signatures of the JC Polyomavirus in Paired Normal and Altered Colorectal Mucosa Indicate a Link with Human Colorectal Cancer, but Not with Cancer Progression · Elena Uleri · 2019 · 14 citations · Cited by this paper
  38. Induction of Brain Tumors by the Archetype Strain of Human Neurotropic JCPyV in a Transgenic Mouse Model · Luis Del Valle · 2021 · 14 citations · Cited by this paper
  39. hMLH1 promoter methylation and JC virus T antigen presence in the tumor tissue of colorectal cancer Israeli patients of different ethnic groups · Yaron Niv · 2010 · 13 citations · Cited by this paper

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