Research map: Urinary biomarkers in muscle-invasive bladder cancer: Current state and open opportunities for neoadjuvant chemotherapy response prediction and patient stratification

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  1. Radical Cystectomy in the Treatment of Invasive Bladder Cancer: Long-Term Results in 1,054 Patients · John P. Stein · 2001 · 3562 citations · Cited by this paper
  2. 2-deoxy-d-ribose: A multifaceted player at the crossroads of cancer metabolism · 2026 · Related
  3. Liquid biopsies come of age: towards implementation of circulating tumour DNA · Jonathan C. M. Wan · 2017 · 2864 citations · Cited by this paper
  4. Activity-dependent metabolic vulnerability in the APPPS1 Alzheimer’s disease mouse model during isoflurane anesthesia · 2026 · Related
  5. Neoadjuvant Chemotherapy plus Cystectomy Compared with Cystectomy Alone for Locally Advanced Bladder Cancer · Herbert Barton Grossman · 2003 · 2691 citations · Cited by this paper
  6. Tailoring pH-responsive charge-conversional interfaces in ionizable lipid-based nanoliposomes for synchronized co-delivery and synergistic therapy of triple-negative breast cancer · 2026 · Related
  7. Bladder cancer · Ashish M. Kamat · 2016 · 1477 citations · Cited by this paper
  8. Preserved motor function and prolonged sensory local anesthesia with novel PLGA microparticles co-encapsulating lidocaine and capsaicin · 2026 · Related
  9. Neoadjuvant Chemotherapy in Invasive Bladder Cancer: Update of a Systematic Review and Meta-Analysis of Individual Patient Data · Claire Louise Vale · 2005 · 1326 citations · Cited by this paper
  10. Iron–quercetin complex induces ex vivo proteomic remodeling in circulating proangiogenic cells derived from human peripheral blood mononuclear cells · 2026 · Related
  11. Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments · Saife Niaz Lone · 2022 · 839 citations · Cited by this paper
  12. Acetonic extract of Saskatoon berry attenuates amyloid-associated neurotoxicity in cellular and Drosophila melanogaster Alzheimer’s disease models · 2026 · Related
  13. Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, Phase II Study · Andrea Necchi · 2018 · 761 citations · Cited by this paper
  14. Design of sunflower trypsin inhibitor 1 derived probes targeting the LDLR and evaluation of their brain delivery · 2026 · Related
  15. Diagnosis and Treatment of Non-Muscle Invasive Bladder Cancer: AUA/SUO Guideline: 2024 Amendment · Jeffrey M. Holzbeierlein · 2024 · 420 citations · Cited by this paper
  16. The chalcone derivative DN-053 attenuates renal fibrosis and inhibits p38 MAPK and STAT3 signaling in renal fibroblasts · 2026 · Related
  17. Perioperative Durvalumab with Neoadjuvant Chemotherapy in Operable Bladder Cancer · Thomas B. Powles · 2024 · 403 citations · Cited by this paper
  18. Predictive Value of Computed Tomography Following Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer · 2023 · Related
  19. Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies · Andrea Necchi · 2019 · 326 citations · Cited by this paper
  20. Blood and Urine Circulating Tumor DNA in Urothelial Bladder Cancer: State of the Art and Clinical Perspective · 2026 · Related
  21. Urinary Biomarkers for Diagnosis of Bladder Cancer · Roger Chou · 2015 · 276 citations · Cited by this paper
  22. Clinical Validation of Chemotherapy Response Biomarker ERCC2 in Muscle-Invasive Urothelial Bladder Carcinoma · David Liu · 2016 · 264 citations · Cited by this paper
  23. Molecular correlates of cisplatin-based chemotherapy response in muscle invasive bladder cancer by integrated multi-omics analysis · Ann Taber · 2020 · 225 citations · Cited by this paper
  24. Staging of bladder cancer · Martin J. Magers · 2018 · 194 citations · Cited by this paper
  25. Different Responses to Neoadjuvant Chemotherapy in Urothelial Carcinoma Molecular Subtypes · Gottfrid Sjödahl · 2021 · 181 citations · Cited by this paper
  26. Preanalytical requirements of urinalysis · Joris Delanghe · 2014 · 173 citations · Cited by this paper
  27. Novel urinary biomarkers for the detection of bladder cancer: A systematic review · Wei Shen Tan · 2018 · 103 citations · Cited by this paper
  28. Perioperative Enfortumab Vedotin and Pembrolizumab in Bladder Cancer · Christof Vulsteke · 2026 · 103 citations · Cited by this paper
  29. Non-muscle invasive bladder cancer risk stratification · Badrinath R. Konety · 2015 · 99 citations · Cited by this paper
  30. A Randomized Phase II Study of Coexpression Extrapolation (COXEN) with Neoadjuvant Chemotherapy for Bladder Cancer (SWOG S1314; NCT02177695) · Thomas W. Flaig · 2021 · 97 citations · Cited by this paper
  31. Urinary exosomal expression of long non-coding RNAs as diagnostic marker in bladder cancer · Fatemeh Yazarlou · 2018 · 93 citations · Cited by this paper
  32. Cell-Free Urine and Plasma DNA Mutational Analysis Predicts Neoadjuvant Chemotherapy Response and Outcome in Patients with Muscle-Invasive Bladder Cancer · Emil Christensen · 2023 · 84 citations · Cited by this paper
  33. Direct quantitative detection for cell-free miR-155 in urine: a potential role in diagnosis and prognosis for non-muscle invasive bladder cancer · Xin Zhang · 2015 · 70 citations · Cited by this paper
  34. Urinary Biomarkers in Bladder Cancer: Where Do We Stand and Potential Role of Extracellular Vesicles · Manuel Castanheira de Oliveira · 2020 · 68 citations · Cited by this paper
  35. Circulating Tumor DNA Analysis in Advanced Urothelial Carcinoma: Insights from Biological Analysis and Extended Clinical Follow-up · Sia V. Lindskrog · 2023 · 68 citations · Cited by this paper
  36. Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers · Selena Y. Lin · 2017 · 67 citations · Cited by this paper
  37. Urinary markers for bladder cancer diagnosis: A review of current status and future challenges · Eisuke Tomiyama · 2023 · 61 citations · Cited by this paper
  38. Recent Developments in the Search for Urinary Biomarkers in Bladder Cancer · Aaron Leiblich · 2017 · 58 citations · Cited by this paper
  39. Noninvasive Detection of Urothelial Carcinoma by Cost-effective Low-coverage Whole-genome Sequencing from Urine-Exfoliated Cell DNA · Shuxiong Zeng · 2020 · 57 citations · Cited by this paper

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