Research map: The chalcone derivative DN-053 attenuates renal fibrosis and inhibits p38 MAPK and STAT3 signaling in renal fibroblasts

Back to the article

Papers in this map

  1. Dapagliflozin in Patients with Chronic Kidney Disease · Hiddo J.L. Heerspink · 2020 · 5532 citations · Cited by this paper
  2. 2-deoxy-d-ribose: A multifaceted player at the crossroads of cancer metabolism · 2026 · Related
  3. TGF-β: the master regulator of fibrosis · Xiao‐Ming Meng · 2016 · 3605 citations · Cited by this paper
  4. Activity-dependent metabolic vulnerability in the APPPS1 Alzheimer’s disease mouse model during isoflurane anesthesia · 2026 · Related
  5. Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases · Marie Cargnello · 2011 · 3320 citations · Cited by this paper
  6. Tailoring pH-responsive charge-conversional interfaces in ionizable lipid-based nanoliposomes for synchronized co-delivery and synergistic therapy of triple-negative breast cancer · 2026 · Related
  7. Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes · George L. Bakris · 2020 · 2886 citations · Cited by this paper
  8. Preserved motor function and prolonged sensory local anesthesia with novel PLGA microparticles co-encapsulating lidocaine and capsaicin · 2026 · Related
  9. Chronic kidney disease and the global public health agenda: an international consensus · Anna Francis · 2024 · 1330 citations · Cited by this paper
  10. Iron–quercetin complex induces ex vivo proteomic remodeling in circulating proangiogenic cells derived from human peripheral blood mononuclear cells · 2026 · Related
  11. Mechanisms of Renal Fibrosis · Benjamin D. Humphreys · 2017 · 1286 citations · Cited by this paper
  12. Acetonic extract of Saskatoon berry attenuates amyloid-associated neurotoxicity in cellular and Drosophila melanogaster Alzheimer’s disease models · 2026 · Related
  13. TGF-β signaling in health, disease and therapeutics · Ziqin Deng · 2024 · 1150 citations · Cited by this paper
  14. Design of sunflower trypsin inhibitor 1 derived probes targeting the LDLR and evaluation of their brain delivery · 2026 · Related
  15. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1 · Wayne A. Border · 1990 · 1002 citations · Cited by this paper
  16. Urinary biomarkers in muscle-invasive bladder cancer: Current state and open opportunities for neoadjuvant chemotherapy response prediction and patient stratification · 2026 · Related
  17. Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy. · Taku Yamamoto · 1993 · 831 citations · Cited by this paper
  18. Fluorinated isoindolinone–amino acid hybrids possessing antiproliferative and antitumor activity in vitro and in vivo · 2026 · Related
  19. Phosphatase‐mediated crosstalk between MAPK signaling pathways in the regulation of cell survival · Melissa R. Junttila · 2007 · 825 citations · Cited by this paper
  20. O-GlcNAc transferase as an oncogenic regulator in hematologic malignancies: Mechanisms, disease contexts, and therapeutic perspectives · 2026 · Related
  21. Kidney fibrosis: from mechanisms to therapeutic medicines · Rongshuang Huang · 2023 · 779 citations · Cited by this paper
  22. Hepatic expression of mature transforming growth factor beta 1 in transgenic mice results in multiple tissue lesions. · Nicholas D. Sanderson · 1995 · 675 citations · Cited by this paper
  23. Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection · Shomyseh Sanjabi · 2017 · 634 citations · Cited by this paper
  24. Obstructive nephropathy and renal fibrosis · Saulo Klahr · 2002 · 557 citations · Cited by this paper
  25. Chalcone Derivatives: Role in Anticancer Therapy · Yang Ouyang · 2021 · 405 citations · Cited by this paper
  26. Chalcone synthesis, properties and medicinal applications: a review · Aluru Rammohan · 2020 · 390 citations · Cited by this paper
  27. Global, regional, and national burden of chronic kidney disease in adults, 1990–2023, and its attributable risk factors: a systematic analysis for the Global Burden of Disease Study 2023 · Patrick B Mark · 2025 · 378 citations · Cited by this paper
  28. Activation of STAT3 integrates common profibrotic pathways to promote fibroblast activation and tissue fibrosis · Debomita Chakraborty · 2017 · 361 citations · Cited by this paper
  29. Origin of myofibroblasts and cellular events triggering fibrosis · Matthias Mack · 2014 · 349 citations · Cited by this paper
  30. Redefining lupus nephritis: clinical implications of pathophysiologic subtypes · Feng Yu · 2017 · 341 citations · Cited by this paper
  31. Smad2 and Smad3 Are Redundantly Essential for the TGF-β–Mediated Regulation of Regulatory T Plasticity and Th1 Development · Tomohito Takimoto · 2010 · 339 citations · Cited by this paper
  32. TGFβ signalling in control of T-cell-mediated self-reactivity · Yury P. Rubtsov · 2007 · 306 citations · Cited by this paper
  33. Increased Renal Production of Transforming Growth Factor-β1 in Patients with Type II Diabetes · Kumar Sharma · 1997 · 274 citations · Cited by this paper
  34. TGF-β signaling in the kidney: profibrotic and protective effects · Angara Sureshbabu · 2016 · 268 citations · Cited by this paper
  35. A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy · Maoyin Pang · 2010 · 262 citations · Cited by this paper
  36. Diverse Role of TGF-β in Kidney Disease · Yue-Yu Gu · 2020 · 253 citations · Cited by this paper
  37. Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis · Yoshitaka Akagi · 1996 · 202 citations · Cited by this paper
  38. The Role of p38α Mitogen-Activated Protein Kinase Activation in Renal Fibrosis · Cosimo Stambe · 2004 · 195 citations · Cited by this paper
  39. Role of SMAD and Non-SMAD Signals in the Development of Th17 and Regulatory T Cells · Ling Lü · 2010 · 192 citations · Cited by this paper

Source: OpenAlex (CC0)